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Blombäck's Essential Guide to Blood Coagulation
A Practical Guide to Diagnosis and Treatment of Hemostatic Disorders

Jovan P. Antovic (Edited by), Antovic (Author), Maria Magnusson (Edited by)

9781394223121, Wiley

Paperback / softback, published 16 October 2025

256 pages
24.9 x 17.8 x 1.5 cm, 0.522 kg

New edition of a concise, comprehensive, easy-to-read pocket book distilling the most clinically up-to-date information on thrombotic and bleeding disorders

In a concise manner, Blombäck’s Essential Guide to Blood Coagulation distills the most clinically up-to-date information on thrombotic and bleeding disorders, including the latest treatment strategies for key conditions and diseases. This book covers both the stable and the acute stages of hereditary and acquired bleeding and thrombotic disorders in adults, children, and geriatric patients. It also highlights the laboratory tests that can aid in diagnosing and identifying the cause of bleeding and/or thrombosis in a patient.

The book is organized into four main sections, each featuring numerous updates in this new edition. The first part introduces the reader to laboratory hemostasis and hemostasis physiology. The second part covers bleeding disorders, including a new chapter on bleeding disorders and aging. The third part discusses thromboembolic disorders, with a new chapter on extracorporeal membrane oxygenation (ECMO). The final section addresses special issues in hemostasis, with new chapters on hemostasis in renal disease, liver disorders, and cancer, as well as updated information on thrombotic thrombocytopenic purpura.

This edition of Blombäck’s Essential Guide to Blood Coagulation also includes updates on:

  • Hemostasis in COVID-19 and vaccine-induced thrombotic thrombocytopenia (VITT), a rare condition observed during pandemic
  • Critical bleeding in different clinical situations and hemostasis in obstetrics and gynecology
  • Platelet disorders, and rare coagulation factor deficiencies, cerebral vein and splanchnic vein thrombosis
  • The greater paradigm shift in the treatment of hereditary bleeding disorders since the last edition was published
  • Laboratory issues in hemostasis, including nomenclature and sampling
  • Specific issues of hemostasis in children

Compact enough to fit into a coat pocket, Blombäck’s Essential Guide to Blood Coagulation is a valuable guide for all those treating patients to expand their knowledge of hemostatic disorders. This text fills a void for the residents, fellow doctors, and practicing physicians who need rapid access to up-to-date information.

Contributors xi

Preface xiii

Abbreviations xv

Part 1: General Hemostasis

1 Overview of normal hemostasis 3
Jovan P. Antovic, Maria Farm, and Charlotte Gran

2 Sampling instructions and preanalytical issues in hemostasis 6
Maria Farm and Charlotte Gran

3 Laboratory investigation 9
Jovan P. Antovic, Maria Farm, Charlotte Gran, Bianca Tesi, and Agneta Wikman

Part 2: Bleeding Disorders

4 Clinical and laboratory investigation of increased bleeding tendency 37
Charlotte Gran and Maria Magnusson

5 Hemophilia 45
Margareta Holmström and Susanna Ranta

6 Von Willebrand disease 52
Tony Frisk and Margareta Holmström

7 Rare bleeding disorders including inherited platelet function defects 58
Cecilia Karlström and Maria Magnusson

8 Specific issues of hemostasis in children – focus on bleeding 65
Maria Farm and Susanna Ranta

9 Hereditary bleeding disorders and aging 71
Jovan P. Antovic, Roza Chaireti, and Joel Ohm

10 Paradigm change – new treatment for hereditary bleeding disorders 75
Maria Magnusson and Susanna Ranta

11 Acquired inhibitors of coagulation factors 81
Roza Chaireti, Margareta Holmström, and Cecilia Karlström

12 Critical bleeding in trauma and surgery 89
Andreas Andersson, Carl Magnus Wahlgren, and Agneta Wikman

13 Gastrointestinal bleeding 93
Maria Magnusson and Per Stål

14 Intracranial bleeding 96
Michael V. Mazya and Michael Nekludov

15 Obstetric massive bleeding 101
Maria Sennström

16 Bleedings associated with anticoagulant and antiplatelet treatment (including reversal of antithrombotic treatment) 103
Margareta Holmström and Joel Ohm

Part 3: Thromboembolic Disorders Venous Thrombosis

17 Venous thromboembolism 111
Joel Ohm

18 Specific issues of hemostasis in children – focus on thrombosis 128
Tony Frisk

19 Thrombotic issues with artificial surfaces 135
Lars Mikael Broman and Moa Simonsson

20 Treatment and prevention of venous thromboembolism 142
Margareta Holmström and Joel Ohm

21 Prevention of cardioembolism in atrial fibrillation 153
Michael V. Mazya and Moa Simonsson

22 Laboratory investigation of anticoagulant treatment 157
Jovan P. Antovic and Maria Farm

23 Ischemic heart disease 163
Moa Simonsson

24 Ischemic stroke and transient ischemic attack (TIA) 168
Michael V. Mazya

25 Peripheral artery disease 173
Carl Magnus Wahlgren

26 Antiplatelet treatment 176
Michael V. Mazya and Moa Simonsson

27 Laboratory investigation of antiplatelet treatment 178
Charlotte Gran and Moa Simonsson

Part 4: Special Hemostasis

28 Hemostasis in rheumatological and systemic disease 183
Aleksandra Antovic and Francesca Faustini

29 Hemostasis in COVID- 19 189
Maria Magnusson and Anna Sjöström

30 Hemostasis in liver disease 192
Maria Magnusson and Per Stål

31 Hemostasis in kidney disease 195
Peter Bárány and Maria Magnusson

32 Hemostasis in obstetrics and gynecology 199
Roza Chaireti and Maria Sennström

33 Hemostasis in cancer 219
Roza Chaireti, Tony Frisk, Charlotte Gran, and Susanna Ranta

34 Emergency conditions associated with hemostatic abnormalities 224
Jovan P. Antovic, Margareta Holmström, and Cecilia Karlström

Index 230

Subject Areas: Clinical & internal medicine [MJ]
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