Biometals in Neurodegenerative Diseases
Mechanisms and Therapeutics

Comprehensive overview of the mechanisms of biometals in neurodegenerative diseases and their role in possible therapeutic targets to treat diseases

Anthony R. White (Edited by), Michael Aschner (Edited by), Lucio G. Costa (Edited by), Ashley I. Bush (Edited by)

9780128045626

Hardback, published 28 April 2017

462 pages
23.4 x 19 x 2.9 cm, 1.13 kg

Approx.442 pages

1. Biometals and Alzheimer’s Disease 2. Copper in Alzheimer’s Disease 3. The Role of Selenium in Neurodegenerative Diseases 4. Does HFE Genotype Impact Macrophage Phenotype in Disease Process and Therapeutic Response? 5. Chemical Elements and Oxidative Status in Neuroinflammation 6. Metals and Neuroinflammation 7. Metals and Prions: Twenty Years of Mining the Awe 8. Manganese and Neurodegeneration 9. Zinc in Autism 10. Metals and Motor Neuron Disease 11. Metals and Lysosomal Storage Disorders 12. Developmental Exposure to Metals and its Contribution to Age-Related Neurodegeneration 13. Metal Biology Associated with Huntington’s Disease 14. Metal-Binding to Amyloid-ß Peptide: Coordination, Aggregation, and Reactive Oxygen Species Production 15. Metals and Mitochondria in Neurodegeneration 16. Metal Transporters in Neurodegeneration 17. Metal Imaging in the Brain 18. Metalloregulation of Protein Clearance: New Therapeutic Avenues for Neurodegenerative Diseases 19. Metals and Autophagy in Neurotoxicity 20. An Overview of Multifunctional Metal Chelators as Potential Treatments for Neurodegenerative Diseases 21. Abnormal Function of Metalloproteins Underlies Most Neurodegenerative Diseases

Subject Areas: Neurosciences [PSAN], Neurology & clinical neurophysiology [MJN]