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Biology of Aminoacyl-tRNA Synthetases
Edited by leaders in the field, this series presents the latest updates on enzymes
Lluis Ribas de Pouplana (Volume editor), Laurie S. Kaguni (Volume editor)
9780128202609, Elsevier Science
Hardback, published 29 October 2020
440 pages
22.9 x 15.1 x 2.8 cm, 0.82 kg
Biology of Aminoacyl-tRNA Synthetases, Volume 48 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on A narrative about our work on the endless frontier of editing, The puzzling evolution of aminoacyl-tRNA synthetases, Structural basis of the tRNA recognition by aminoacyl-tRNA synthetases, Catalytic strategies of aminoacyl-tRNA synthetases, Trans-editing by aminoacyl-tRNA synthetase-like editing domains, Adaptive and maladaptive mistranslation arising from aminoacyl-tRNA synthetases, Non-canonical inputs and outputs of tRNA aminoacylation, Structure and function of multi-tRNA synthetase complexes, Mitochondrial aminoacyl-tRNA synthetases, Non-canonical functions of human cytoplasmic tyrosyl-, tryptophanyl- and other aminoacyl-tRNA synthetases, and much more.
1. The endless frontier of tRNA synthetases Paul Schimmel 2. The evolution of aminoacyl-tRNA synthetases: From dawn to LUCA Lluís Ribas de Pouplana 3. Putting amino acids onto tRNAs: The aminoacyl-tRNA synthetases as catalysts Rebecca W. Alexander and Tamara L. Hendrickson 4. Trans-editing by aminoacyl-tRNA synthetase-like editing domains Alexandra B. Kuzmishin Nagy, Marina Bakhtina and Karin Musier-Forsyth 5. Noncanonical inputs and outputs of tRNA aminoacylation Marine Hemmerle, Marion Wendenbaum, Guillaume Grob, Nathaniel Yakobov, Nassira Mahmoudi, Bruno Senger, Sylvain Debard, Frédéric Fischer and Hubert Dominique Becker 6. Structures and functions of multi-tRNA synthetase complexes Myung Hee Kim and Sunghoon Kim 7. Mitochondrial aminoacyl-tRNA synthetases Joseph Chihade 8. Non-canonical functions of human tytoplasmic tyrosyl-, tryptophanyl- and other aminoacyl- tRNA synthetases Keisuke Wakasugi and Takumi Yokosawa 9. Aminoacyl-tRNA synthetases in cell signaling Peng Yao and Paul L. Fox 10. Human diseases linked to cytoplasmic aminoacyl-tRNA synthetases Lei Jiang, Julia Jones and Xiang-Lei Yang 11. Aminoacyl-tRNA synthetases as drug targets Maria Lukarska and Andrés Palencia 12. Engineering aminoacyl-tRNA synthetases for use in synthetic biology Natalie Krahn, Jeffery Tharp, Ana Crnkovic and Dieter Söll 13. Novel functions of cytoplasmic aminoacyl-tRNA synthetases shaping the hallmarks of cancer Justin Wang and Xiang-Lei Yang
Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Biochemistry [PSB], Life sciences: general issues [PSA], Biophysics [PHVN]
