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Biologically Active Peptides
From Basic Science to Applications for Human Health
Offers a comprehensive, interdisciplinary examination of bioactive peptides and their growing role in medicine, from basic science to methods and technology
Fidel Toldra (Edited by), Jianping Wu (Edited by)
9780128213896, Elsevier Science
Paperback, published 25 June 2021
818 pages, 150 illustrations (100 in full color)
23.4 x 19 x 4.9 cm, 1.65 kg
Biologically Active Peptides: From Basic Science to Applications for Human Health stands as a comprehensive resource on bioactive peptide science and applications. With contributions from more than thirty global experts, topics discussed include bioactive peptide science, structure-activity relationships, best practices for their study and production, and their applications. In the interdisciplinary field of bioactive peptides, this book bridges the gap between basic peptide chemistry and human physiology, while reviewing recent advances in peptide analysis and characterization. Methods and technology-driven chapters offer step-by-step guidance in peptide preparation from different source materials, bioactivity assays, analysis and identification of bioactive peptides, encoding bioactive peptides. Later, applications across disease areas and medical specialties are examined in-depth, including the use of bioactive peptides in treating obesity, diabetes, osteoporosis, mental health disorders, food allergies, and joint health, among other disorders, as well as bioactive peptides for sensory enhancement, sports and clinical nutrition, lowering cholesterol, improving cardiovascular health, and driving advances in biotechnology.
1. Bioactive peptides in health and disease: An overview 2. Enzymatic mechanisms for the generation of bioactive peptides 3. Methodologies: Novel technologies in bioactive peptides production and stability 4. Methodologies for extraction and separation of short-chain bioactive peptides 5. Methodologies for peptidomics: Identification and quantification 6. Methodologies for bioactivity assay: Biochemical study 7. Methodologies for bioactivity assay: Cell study 8. Methodologies for bioactivity assay: Animal study 9. Methodologies for bioavailability assessment 10. Methodologies for Studying the Structure-function Relationship of Food-derived Peptides with Biological Activities 11. Methodologies for study of Mechanisms of action: Biochemistry approach 12. Methodologies for study of Mechanisms of action: Multi-omic approach 13. Methodologies for study of mechanisms of action: Gene editing approach 14. Databases of bioactive peptides 15. Technologies for bioactive peptides protection and delivery 16. Plant sources of bioactive peptides 17. Generation of Bioactivities from Proteins of Animal Sources by Enzymatic Hydrolysis and the Maillard Reaction 18. Sustainable alternative sources of bioactive peptides 19. Applications in nutrition: Mineral-binding 20. Applications in nutrition: Clinical nutrition 21. Applications in nutrition: Sport nutrition 22. Applications in nutrition: Cholesterol lowering activity 23. Applications in nutrition: Peptides as taste enhancers 24. Applications in medicine: Cardiovascular benefit (ACE and renin inhibitory peptides) 25. Applications in medicine: Diabetes prevention (hypoglucemic peptides) 26. Applications in medicine: Obesity (including satiety control) 27. Food-derived osteogenic peptides towards osteoporosis 28. Applications in medicine: Mental health 29. Applications in medicine: Food allergy 30. Applications in medicine: Joint health 31. Applications in food technology: Antimicrobial peptides
