Biointegration of Medical Implant Materials
Science and Design

Chandra P. Sharma (Edited by)

9780081014714, Elsevier Science

Paperback / softback, published 19 August 2016

424 pages
23.3 x 15.6 x 2.7 cm, 0.6 kg

Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue.

Biointegration of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering.

With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector.

Biointegration: An introduction. Part 1 Soft tissue biointegration: Biocompatibility of engineered soft tissue created by stem cells
Replacement materials for facial reconstruction at the soft tissue-bone interface
Corneal tissue engineering
Tissue engineering for small-diameter vascular graft
Stem cells for organ regeneration. Part 2 Drug delivery: Materials facilitating protein drug delivery and vascularisation
Inorganic nanoparticles for targeted drug delivery
Alginate-based drug delivery devices
Functionalised nanoparticles for targeted drug delivery. Part 3 Design considerations: Biocompatibility of Materials and its relevance to drug delivery and tissue engineering
Mechanisms of failure of medical implants during long-term use
Rapid prototyping in biomedical Engineering: Structural intricacies of biological materials.

Subject Areas: Materials science [TGM], Biotechnology [TCB], Biomedical engineering [MQW], Medical equipment & techniques [MBG]