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Bioinformatics Algorithms
Design and Implementation in Python

Provides a basis for understanding algorithm development and implementation in Python, with limited computer programming experience needed

Miguel Rocha (Author), Pedro G. Ferreira (Author)

9780128125205, Elsevier Science

Paperback, published 12 June 2018

400 pages
23.4 x 19 x 2.5 cm, 0.86 kg

Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming the most popular language in the bioinformatics field. Readers will find the tools they need to improve their knowledge and skills with regard to algorithm development and implementation, and will also uncover prototypes of bioinformatics applications that demonstrate the main principles underlying real world applications.

Part I: Bioinformatics Basics1. Introduction2. Relevant Biological Concepts3. Algorithms and Python: Introduction4. Optimization: Basic Concepts and Algorithms

Part II: Sequence Analysis Algorithms5. Basic Processing of DNA Sequences: Transcription and Translation6. Finding Patterns in Sequences7. Pairwise Sequence Alignment8. Searching Similar Sequences in Databases9. Multiple Sequence Alignment10. Phylogenetic Analysis11. Motif Discovery12. Hidden Markov Models13. Stochastic Algorithms

Part III: Graph and Large-Scale Sequencing Data Processing14. Graphs15. Biological Networks16. Assembling Reads into Genomes17. Matching Reads to Reference Sequences

Part IV: Conclusions18. Further Reading and Resources19. Final Words

Appendix: Python Reference Functions

Subject Areas: Biomedical engineering [MQW], Medicine: general issues [MB]

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