Biochemistry and Molecular Biology of Parasites

Joseph Marr (Edited by), Miklos Muller (Edited by)

9780124733459, Elsevier Science

Hardback, published 6 September 1995

349 pages
22.9 x 15.2 x 2.5 cm, 0.74 kg

The study of parasitic organisms at the molecular level has yielded fascinating new insights of great medical, social, and economical importance, and has pointed the way for the treatment and prevention of the diseases they cause. Biochemistry and Molecular Biology of Parasites presents an up-to-date account of this modern scientific discipline in a manner that allows and encourages the reader to place the biochemistry and molecular biology of these organisms in their biological context. The chapters are cross-referenced and grouped in an arrangement that provides a fully integrated whole, and permits the reader to create a composite of the biochemical function of these organisms.
Individual chapter includes those devoted to metabolism, in both aerobic and anaerobic protozoa; antioxidant mechanisms; parasite surfaces; organelles; invasion mechanisms; and chemotherapy. The helminths are discussed not only from the point of view of their cellular biochemistry and metabolism, but also with respect to both their integrated functions such as neurochemistry, structure and functions of surfaces, and reproduction. Written by expert investigators, this book will be of interest to all experienced researchers, graduate students, and to the newcomer eager to become familiar with the biochemistry and molecular biology of parasites.

E. Ullu and T. Nilsen, Molecular Biology of Protozoan and Helminth Parasites.
F.R. Opperdoes, Carbohydrate and Energy Metabolism in Aerobic Protozoa.
G.H. Coombs and M. Muller, Energy Metabolism in Anaerobic Protozoa.
R. Komuniecki and B.G. Harris, Carbohydrate and Energy Metabolism in Helminths.
M.J. North and B.C. Lockwood, Amino Acid and Protein Metabolism.
R.L. Berens, E.C. Krug, and J.J. Marr, Purine and Pyrimidine Metabolism.
C.J. Bacchi and N. Yarlett, Polyamine Metabolism.
W.R. Fish, Lipid and Membrane Metabolism of the Malaria Parasite and the African Trypanosome.
R. Docampo, Antioxidant Mechanisms.
J.W. Tracy and E.A. Vande Waa, Xenobiotic Metabolism.
S.J. Turco, Surface Constituents of Kinetoplastid Parasites.
D.P. Thompson and T.G. Geary, The Structure and Function of Helminth Surfaces.
M. Parsons, Protozoan Cell Organelles.
R.E. Davis and A.O.W. Stretton, Neurotransmitters of Helminths.
H.R. Gamble, R.H. Fetterer, and J.F. Urban, Reproduction and Development of Helminths.
J.F. Dubremetz and J.H. McKerrow, Invasion Mechanisms.
J.J. Marr and B. Ullman, Concepts of Chemotherapy.
Subject Index.

Subject Areas: Applied ecology [RNC], Parasitology [non-medical PSGH], Molecular biology [PSD], Biochemistry [PSB], Medical parasitology [MMFP]