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Basic Virology
Martinez J. Hewlett (Author), David Camerini (Author), David C. Bloom (Author)
9781119314059, Wiley
Paperback / softback, published 13 May 2021
576 pages
26.9 x 21.3 x 2.8 cm, 1.497 kg
The foundational textbook on the study of virology Basic Virology, 4th Edition cements this series’ position as the leading introductory virology textbook in the world. It’s easily read style, outstanding figures, and comprehensive coverage of fundamental topics in virology all account for its immense popularity. This undergraduate-accessible book covers all the foundational topics in virology, including: The 4th edition includes new information on the SARS, MERS and COVID-19 coronaviruses, hepatitis C virus, influenza virus, as well as HIV and Ebola. New virological techniques including bioinformatics and advances in viral therapies for human disease are also explored in-depth. The book also includes entirely new sections on metapneumoviruses, dengue virus, and the chikungunya virus.
Preface xxi Acknowledgements xxvii Part I Virology and Viral Disease 1 Chapter 1 Introduction – The Impact of Viruses on Our View of Life 3 Chapter 2 An Outline of Virus Replication and Viral Pathogenesis 15 Chapter 3 Virus Disease in Populations and Individual Animals 27 Chapter 4 Patterns of Some Viral Diseases of Humans 43 Part II Basic Properties of Viruses and Virus–cell Interaction 65 Chapter 5 Virus Structure and Classification 67 Chapter 6 The Beginning and End of the Virus Replication Cycle 85 Chapter 7 The Innate Immune Response: Early Defense Against Pathogens 105 Chapter 8 Strategies to Protect Against and Combat Viral Infection 131 Part III Working with Virus 153 Chapter 9 Visualization and Enumeration of Virus Particles 155 Chapter 10 Replicating and Measuring Biological Activity of Viruses 163 Chapter 11 Physical and Chemical Manipulation of the Structural Components of Viruses 181 Chapter 12 Characterization of Viral Products Expressed in the Infected Cell 197 Chapter 13 Viruses Use Cellular Processes to Express their Genetic Information 217 Part IV Replication Patterns of Specific Viruses 245 Chapter 14 Replication of Positive‐Sense RNA Viruses 247 Chapter 15 Replication Strategies of RNA Viruses Requiring RNA‐directed mRNA Transcription as the First Step in Viral Gene Expression 277 Chapter 16 Replication Strategies of Small and Medium‐sized DNA Viruses 307 Chapter 17 Replication of Some Nuclear‐replicating Eukaryotic DNA Viruses with Large Genomes 335 Chapter 18 Replication of Cytoplasmic DNA Viruses and “Large” Bacteriophages 363 Chapter 19 Retroviruses: Converting RNA to DNA 385 Chapter 20 Human Immunodeficiency Virus Type 1 (HIV‐1) and Related Lentiviruses 403 Chapter 21 Hepadnaviruses: Variations on the Retrovirus Theme 415 Part V Molecular Genetics of Viruses 437 Chapter 22 The Molecular Genetics of Viruses 439 Chapter 23 Molecular Pathogenesis 467 Chapter 24 Viral Bioinformatics 477 Chapter 25 Viruses and the Future – Problems and Promises 489 Appendix – Resource Center 503 Technical Glossary 509 Index 533
Subject Areas: Biology, life sciences [PS]
