Basic Mutagenicity Tests
UKEMS Recommended Procedures

A summary of the essential texts that must be performed on all new compounds before they can be registered for use in the UK.

David J. Kirkland (Edited by)

9780521019057, Cambridge University Press

Paperback, published 8 September 2005

160 pages
22.9 x 15.4 x 1.1 cm, 0.25 kg

This volume provides a brief but important summary of the essential tests that need to be performed on all new compounds, whether they be new drugs, pesticides or food additives, before they can be registered for use in the United Kingdom. These basic tests for mutagenicity were originally drawn up by the United Kingdom Environmental Mutagen Society (UKEMS) in 1983. They have now been fully revised by expert working groups from academia and industry under the auspices of UKEMS.

Steering group
Contributors
List of abbreviations
1. Introduction D. J. Kirkland
2. Bacterial mutation assays D. G. Gatehouse
3. Metaphase chromosome aberration assays in vitro D. Scott
4. Gene mutation assays in cultured mammalian cells J. Cole
5. In vivo cytogenetics assays M. Richold
Index.

Subject Areas: Biochemistry [PSB], Scientific standards [PDD]