Autophagy and Senescence in Cancer Therapy

Presents the latest release in the Advances in Cancer Research series, with this volume focusing on autophagy and senescences in tumor dormancy

Paul B. Fisher (Volume editor), David A. Gewirtz (Volume editor)

9780128241585

Hardback, published 15 April 2021

382 pages
22.9 x 15.2 x 2.6 cm, 0.75 kg

Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more.

1.Autophagy and senescence in cancer therapy
Nipa H. Patel, Sarah Bloukh, Enas Alwohosh, Ahmad Alhesa, Tareq Saleh, and David A. Gewirtz
2. Targeting the stress support network regulated by autophagy and senescence for cancer treatment
Jaejin Kim, Yeonghyeon Lee, Kyeonghwan Roh, Mi-Sung Kim, and Chanhee Kang
3. Autophagy and senescence, converging roles in pathophysiology as seen through mouse models
Andrew R.J. Young, Liam D. Cassidy, and Masashi Narita
4. Autophagy and senescence: Insights from normal and cancer stem cells
Sarmistha Talukdar, Swadesh K. Das, Luni Emdad, and Paul B. Fisher
5. The role of autophagy in escaping therapy-induced polyploidy/senescence
Magdalena Dudkowska, Karolina Staniak, Agnieszka Bojko, and Ewa Sikora
6. Autophagy and PTEN in DNA damage-induced senescence
Arishya Sharma and Alexandru Almasan
7. Cellular senescence and tumor promotion: Role of the Unfolded Protein Response
Olivier Pluquet and Corinne Abbadie
8. mTOR as a senescence manipulation target: A forked road
Sarah Saoudaoui, Monique Bernard, Guillaume B. Cardin, Nicolas Malaquin, Apostolos Christopoulos, and Francis Rodier

Subject Areas: Virology [non-medical PSGL], Cellular biology [cytology PSF], Genetics [non-medical PSAK], Immunology [MJCM]