Atomic Force Microscopy for Nanoscale Biophysics
From Single Molecules to Living Cells

A systematic and comprehensive presentation of atomic force microscopy and its biomedical applications

Mi Li (Author)

9780323953603

Paperback / softback, published 22 February 2023

336 pages
22.9 x 15.2 x 2.2 cm, 0.63 kg

Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.

1. Fundamentals and methods of AFM for biophysics 2. Imaging and force detection of DNA by AFM 3. High-resolution imaging and force spectroscopy of membrane proteins by AFM 4. Characterizing the nanostructures and properties of hydrogels by AFM 5. Detecting the behaviours of single virus by AFM 6. Nanoscale imaging and force probing of single microbial cells by AFM 7. Investigating the structures and mechanics of single animal cells by AFM 8. Combining AFM with complementary techniques: Hybrid AFM for biophysics 9. Conclusion and future perspectives

Subject Areas: Cellular biology [cytology PSF], Molecular biology [PSD], Biochemistry [PSB], Biophysics [PHVN]