• Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis (Hardback) 9780444635723
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Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

As a comprehensive reference, this book covers applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis, providing a diverse group of examples that will allow readers to discover not only the potential of high-resolution MS in their sector, but also allow insights into advances in other fields

Sandra Perez (Volume editor), Peter Eichhorn (Volume editor), Damia Barcelo (Volume editor)

9780444635723, Elsevier Science

Hardback, published 1 June 2016

524 pages
22.9 x 15.1 x 3.1 cm, 0.67 kg

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance.

This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants.

This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications.

This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS.

Instrumentation

  1. Orbitrap Mass Spectrometry: Evolution and Applicability

    2. Claudia P.B. Martins, Maciej Bromirski, Mari C. Prieto Conaway and Alexander A. Makarov

  2. Advances in Time of Flight Mass Spectrometry

    3. John C. Fjeldsted

  3. Ambient Ionization-High Resolution Mass Spectrometry: Environmental, Food, Forensic and Doping Analysis.

    4. Raquel Seró, Óscar Núñez and Encarnación Moyano

    Target Analysis, Identification, and Suspect Screening

  4. High Resolution Mass Spectrometry in Doping Control

    5. Georgina Balcells, Oscar J. Pozo and Rosa Ventura

  5. Application of LC-Time of Flight and Orbitrap-MS/MS for Pesticide Residues in Fruits and Vegetables

    6. Lukasz Rajski, María del Mar Gómez Ramos and Amadeo R. Fernández-Alba

  6. Identification of Sildenafil Designer Analogues Found in Dietary Supplements

    7. Xiaowei Ge, Chee-Leong Kee, Yun Zeng and Min-Yong Low

  7. High-Resolution Mass Spectrometry in Metabolite Identification

    8. Mayurbhai Kathadbhai Ladumor, Shristy Tiwari, Amol Patil, Krishna Bhavsar, Shalu Jhajra, Bhagwat Prasad and Saranjit Singh

  8. LC-TOF-MS for the Identification of Environmental Metabolites and Degradation Products

    9. Imma Ferrer, Jeffrey H. Writer, Olya S. Keen, Yaal Lester, Juan A. Padilla-Sánchez, Carolina Fernández-Ramos and E. Michael Thurman

  9. Application of Orbitrap Mass Spectrometry for the Identification of Transformation Products of Trace Organic Contaminants Formed in the Environment

    10. Carsten Prasse and Thomas A. Ternes

  10. High Resolution-Mass Spectrometry Identification of Micropollutants Transformation Products Produced During Water Disinfection with Chlorine and Related Chemicals

    11. Iria González-Mariño, Inmaculada Carpinteiro, Rosario Rodil, Isaac Rodríguez and José Benito Quintana

  11. Discovery of New Emerging DBPs by High Resolution Mass Spectrometry

    12. Susan D. Richardson and Cristina Postigo

  12. Suspect Screening of Pharmaceuticals and Related Bioactive Compounds, Their Metabolites and Their Transformation Products in the Aquatic Environment, Biota and Humans Using LC-HR-MS Techniques

    13. Jaume Aceña, Nubia Heuett, Piero Gardinali and Sandra Pérez

    Non-Target Analysis

  13. Non-Target Analysis of Environmental Samples Based on Liquid Chromatography Coupled to High Resolution Mass Spectrometry (LC-HRMS)

    14. Pablo Gago-Ferrero, Emma L. Schymanski, Juliane Hollender and Nikolaos S. Thomaidis

  14. Non-Targeted Analysis of Persistent Organic Pollutants by Mass Spectrometry and GC×GC

    15. Xavier Ortiz Almirall, Miren Pena Abaurrea, Karl J. Jobst and Eric J. Reiner

  15. High Resolution Mass Spectrometry in the Effect-Directed Analysis of Water Resources

    16. Martin Krauss

    Conclusions

  16. Conclusions and Future Directions Peter Eichhorn and Sandra Pérez

Subject Areas: Spectrum analysis, spectrochemistry, mass spectrometry [PNFS], Forensic science [JKVF1]
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