Antipsychotics and their Side Effects

This book comprehensively reviews the adverse effects of all commonly used older and newer antipsychotics and provides clinician-friendly monitoring resources and recommendations.

David M. Gardner (Author), Michael D. Teehan (Author), Ross Baldessarini (Foreword by)

9780521132084, Cambridge University Press

Paperback, published 11 November 2010

228 pages, 3 b/w illus. 102 tables
25.7 x 17.3 x 1.4 cm, 0.64 kg

'I know of no other book that covers the topic so completely, lucidly, and succinctly. It is an exceptionally praiseworthy piece of work that should be on the short list of 'must have' books for every physician, nurse, and pharmacist who deals with antipsychotic medications. I will add it to my own personal library with pleasure.' Eliot Lawrence Gardner, Chief, Neuropsychopharmacology Section, National Institute on Drug Abuse, Johns Hopkins University

With the remarkable expansion in the use of antipsychotics, concerns about their immediate, intermediate, and long-term adverse effects have intensified. Despite this, studies consistently show that monitoring of patients taking antipsychotics can be inadequate, haphazard, or worse. This book provides a comprehensive review of the adverse effects of this pharmacologically complex therapeutic class, covering all commonly used conventional and atypical agents. In the first section, each chapter provides background information about an adverse effect, reviews the evidence linking the effect to various antipsychotics, and provides specific detection and monitoring recommendations. The second section provides unique monitoring guides for each antipsychotic. The third section provides the clinician with a program to monitor patients over the long-term. By supporting rational treatment decisions and systematic adverse effect monitoring, Antipsychotics and their Side Effects provides the clinician with the necessary information and tools for optimizing the safe and effective long-term use of antipsychotic drugs.

Foreword
Preface
Purpose, development, and limitations of Antipsychotics and their Side Effects
Guide to using Antipsychotics and their Side Effects
About the authors
About the cover
Part I. Antipsychotic Side Effects and Monitoring Implications: 1. Introduction
2. Agranulocytosis and other blood dyscrasias
3. Anticholinergic effects
4. Diabetes
5. Dyslipidemia
6. Extrapyramidal symptoms
7. Hepatic effects
8. Neuroleptic malignant syndrome
9. Obesity and weight gain
10. Ocular effects
11. Prolactin effects
12. QT prolongation, arrhythmias, and sudden cardiac death
13. Sedation and sleep disturbances
14. Seizures
15. Sexual dysfunction
16. Sialorrhea
17. Skin effects and hypersensitivity reactions
18. Tardive dyskinesia
19. Urinary incontinence
20. Venous thromboembolism
21. Vital signs
Part II. Summary Monitoring Recommendations for Individual Antipsychotics: 22. Aripiprazole
23. Chlorpromazine
24. Clozapine
25. Flupenthixol
26. Fluphenazine
27. Haloperidol
28. Loxapine
29. Methotrimeprazine
30. Molindone
31. Olanzapine
32. Paliperidone
33. Pericyazine
34. Perphenazine
35. Pimozide
36. Pipotiazine palmitate
37. Quetiapine
38. Risperidone
39. Thioridazine
40. Thiothixene
41. Trifluoperazine
42. Ziprasidone
43. Zuclopenthixol
Part III. General Monitoring Form for Patients Taking Antipsychotics
Index.

Subject Areas: Clinical psychology [MMJ], Psychiatry [MMH], Pharmacology [MMG]