Anticandidal Therapeutics
Discovery and Development

Provides a previous background on fungal infection in humans and animals in addition to background on fungal resistance to drugs

Awanish Kumar (Author), Anubhuti Jha (Author)

9780443187445, Elsevier Science

Paperback / softback, published 23 January 2023

196 pages
23.5 x 19 x 1.4 cm, 0.45 kg

Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time. There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida. Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs. Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies. In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.

1. History of infection 2. Brief introduction on infection 3. Fungal diseases and antifungal drugs 4. Multidrug transporters of fungal pathogen Candida 5. Essential anticandidal targets 6. Stages of anticandidal agent development 7. Recent trends and progress in antifungal translational research 8. Clinical status of anticandidal therapeutic agents 9. Drug repurposing for development of effective anticandidals 10. Commercial aspects of drug development 11. Challenges and future prospects

Subject Areas: Mycology, fungi [non-medical PSQ]