Amyotrophic Lateral Sclerosis
A Synthesis of Research and Clinical Practice

A comprehensive, practical and thought-provoking account of motor neuron disease.

Andrew Eisen (Author), Charles Krieger (Author)

9780521581035, Cambridge University Press

Hardback, published 1 October 1998

324 pages, 51 b/w illus. 40 tables
23.4 x 15.6 x 1.9 cm, 0.63 kg

'The volume is amply illustrated and balanced in its approach. It is strongly recommended to all physicians, researchers and health care professionals involved in the management of ALS sufferers and their carers. It will also be a useful reference resource for medical libraries.' Neuromuscular Disorders

Amyotrophic lateral sclerosis (ALS), otherwise known as Lou Gehrig's or motor neuron disease, is one of several degenerative diseases of the ageing nervous system. Commonly affecting those in their mid-50s and beyond, it is a progressive illness resulting in death within a few years. This text neatly synthesizes the recent explosion of research into this particular condition to construct a detailed and comprehensive overview. From its epidemiology, molecular biology and pathophysiology right through to clinical assessment and care, Professor Eisen and Dr Krieger use their research expertise and extensive clinical experience to provide this practical and thought-provoking account.

Foreword
Preface
Acknowledgements
Abbreviations
1. Epidemiological considerations
2. The clinical spectrum of ALS
3. The pathology of ALS
4. Pathogenic mechanisms in ALS
5. The role of clinical neurophysiology in ALS
6. The application of imaging techniques
7. ALS therapy, therapeutic trials and neuroprotection
8. The overlap syndromes
References
Index.

Subject Areas: Neurology & clinical neurophysiology [MJN]