Amino Acids and Peptides

Advanced undergraduate/graduate text for chemists and biochemists working on amino acids and peptides.

G. C. Barrett (Author), D. T. Elmore (Author)

9780521468275, Cambridge University Press

Paperback, published 29 October 1998

244 pages, 192 b/w illus. 10 tables
24.6 x 17.4 x 1.5 cm, 0.405 kg

'… a useful adjunct to advanced undergraduate courses looking for a text.' European Peptide Society Newsletter

This text is suitable for advanced undergraduate and beginning graduate students in chemistry and biochemistry studying amino acids and peptides. The authors concentrate on amino acids and peptides without detailed discussions of proteins, although the book gives all the essential background chemistry, including sequence determination, synthesis and spectroscopic methods, to enable the reader to appreciate protein behaviour at the molecular level. The approach is intended to encourage the reader to cross classical boundaries, as in the later chapters on the biological roles of amino acids and the design of peptide-based drugs. For example, there is a section on the enzyme-catalysed synthesis of peptides, with suitable examples, an area often neglected in texts describing peptide synthesis. This modern text will be of value in the amino acid, peptide and protein field, to advanced undergraduates, graduate students and research workers.

1. Introduction
2. Peptide conformations
3. Physicochemical properties of amino acids and peptides
4. Reactions and analytical methods for amino acids and peptides
5. Determination of primary structure of peptides
6. Synthesis of amino acids
7. Synthesis of peptides
8. Biological roles of amino acids and peptides
9. Some aspects of amino acid and peptide drug design

Subject Areas: Biochemistry [PSB], Chemistry [PN]