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Allergy, Immunity and Tolerance in Early Childhood
The First Steps of the Atopic March

Explains the rationale, possibilities, limitations, and perspectives on the primary and secondary prevention of allergic diseases, including input from global experts in the field

Hans Ulrich Wahn (Edited by), Hugh A. Sampson (Edited by)

9780124202269

Hardback, published 5 October 2015

408 pages
22.9 x 15.1 x 2.7 cm, 0.81 kg

Allergy, Immunity and Tolerance in Early Childhood: The First Steps of the Atopic March provides valuable insights on the atopic diseases, including asthma, allergic rhinitis, atopic dermatitis, and food allergies, which have developed into major health problems in most parts of the world.

As the natural history of these chronic diseases has been extensively studied, including their major genetic, environmental, and lifestyle determinants and potential protective factors, the book presents tactics on how pediatric allergists can provide early intervention. In addition, the book unites key, global experts in the field who summarize their collective, and current, knowledge of the early stage of the "Atopic March", along with novel ideas for potential options of prevention.

1. Genes for allergic manifestation
2. Epigenetics
3. What have we missed already by birth
4. B Cell Development
5. Maturation of T cell functions
6. The innate immune system
7. Atopic dermatitis
8. Wheeze and asthma
9. Pollen allergy
10. Lung function
11. Breast –always best?
12. Novel routes for antiallergic vaccination
13. Novel ideas for antiallergic vaccines
14. Antiallergic treatment of the skin
15. Systemic pharmacotherapy
16. Antiviral strategies
17. Adverse reactions of the gut
18. Hydrolysate diets
19. Probiotics-Prebiotics
20. Microbial Compounds
21. Avoidance of allergens

Subject Areas: Paediatric medicine [MJW], Allergies [MJCM1]

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