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Allergens and Respiratory Pollutants
The Role of Innate Immunity
Marc A. Williams (Edited by)
9780081017166, Elsevier Science
Paperback / softback, published 19 August 2016
312 pages
23.3 x 15.6 x 2 cm, 0.45 kg
Allergens and respiratory pollutants is a collection of 12 authoritative papers that draws upon the collective expertise of world leaders in the fields of innate immunity, immunotoxicology and pulmonary biology. The book critically explores the biological and immunological mechanisms that contribute to immune dysfunction on exposure to allergens and the susceptibility to infectious disease on exposure to ambient pollutants. The clinical relevance of exposure to ambient airborne xenobiotics is critically discussed and collectively, this book provides an educational forum that links the health effects of environmental exposures, immune dysfunction and inflammatory airways disease.
List of illustrations Editor's note About the editor and contributors Chapter 1: An introduction to allergic inflammation and the innate immune sensing of dangerous ambient pollutants by the dendritic cell Chapter 2: Asthma: primary immunomodulatory pathways Chapter 3: Environmental lung injury and pattern recognition receptors Chapter 4: Asthma exacerbations: a paradigm of synergy between allergens, pollutants and viruses Chapter 5: Bronchial hyperresponsiveness and lung inflammation induced by allergic immune response and oxidative stress: role of innate and adaptive immune responses Chapter 6: Effects of air pollutants on allergic sensitization through the airway Chapter 7: Particulate matter and oxidative stress: dangerous partners in inflammation, vascular dysfunction and innate immunity Chapter 8: Diesel exhaust particles and the airway epithelial cell - dendritic cell interface in the control of immune homeostasis Chapter 9: Role of macrophages in adverse pulmonary effects of particulate pollutants Chapter 10: Particulate air pollution and vulnerability to respiratory infections in children Chapter 11: The intersection of respiratory syncytial virus infection, innate immunity and allergic lung disease Chapter 12: Interactions between allergens and dendritic cells: pattern recognition receptors and their function in the pathogenesis of allergic respiratory diseases Index
Subject Areas: Popular medicine & health [VFD], Allergies [MJCM1]
