Alcohol and Its Biomarkers
Clinical Aspects and Laboratory Determination

Guide to all currently known alcohol biomarkers, their clinical application and the laboratory methods used to detect them

Amitava Dasgupta (Author)

9780128003398, Elsevier Science

Hardback, published 23 February 2015

312 pages
23.4 x 19 x 2.3 cm, 0.91 kg

"...a concise and well written book that delivers on its promise of presenting a comprehensive overview of alcohol and its biomarkers...a useful reference for health care professionals and laboratorians…" --Lab Medicine

Alcohol and Its Biomarkers: Clinical Aspects and Laboratory Determination is a concise guide to all currently known alcohol biomarkers, their clinical application, and the laboratory methods used to detect them. Pathologists can use this resource to understand the limitations and cost factors associated with each method for determining certain alcohol biomarkers. In addition, interferences in these determinations are discussed, so that clinicians can understand the causes of falsely elevated biomarkers and pathologists and laboratory scientists can potentially eliminate them. The book focuses on the analytical methods used to detect alcohol in blood and urine, the limitations of alcohol determination using enzymatic methods, and the differences between clinical and forensic alcohol measurement. Chapters also cover cutting-edge alcohol biomarkers for potential use.

1. Alcohol: Use, Abuse and Issues with Blood Alcohol Level
2. Genetic Aspect of Alcohol Metabolism and Drinking Behavior
3. Measurement of Alcohol Levels in Body Fluids and Transdermal Alcohol Sensors
4. Alcohol Biomarkers: An Overview
5. Liver Enzymes as Alcohol Biomarkers
6. Mean Corpuscular Volume, and Carbohydrate Deficient Transferrin as Alcohol Biomarker
7. Beta-hexosaminidase, Acetaldehyde-Protein Adducts and Dolichol as Alcohol Biomarkers
8. Direct Alcohol Biomarkers: Ethyl Glucuronide, Ethyl Sulfate, Fatty Acid Ethyl Esters and Phosphatidylethanol
9. Less commonly Used Alcohol Biomarkers and Proteomics in Alcohol Biomarker Discovery
10. Genetic Markers of Alcohol Use Disorder

Subject Areas: Biochemistry [PSB], Genetics [non-medical PSAK], Physiology [MFG]