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Albinism in Africa
Historical, Geographic, Medical, Genetic, and Psychosocial Aspects

In-depth reference for understanding and treating patients of human albinism in Africa, featuring thorough examinations of the historical, geographic, psychosocial, genetic and medical aspects

Jennifer Kromberg (Edited by), Prashiela Manga (Edited by)

9780128133163, Elsevier Science

Paperback, published 4 January 2018

358 pages
23.4 x 19 x 2.3 cm, 0.77 kg

Albinism in Africa: Historical, Geographic, Medical, Genetic, and Psychosocial Aspects provides the first in-depth reference for understanding and treating patients of human albinism in Africa. Leading international contributors examine the historical, geographic, psychosocial, genetic and molecular considerations of importance in effectively and sensitively managing this genetic disorder. Foundational chapters covering the historical and psychosocial aspects of albinism are supplemented by discussions of the pathobiology of the disease, as well as a thorough analysis of the genetics of skin pigmentation, eye pigmentation, hair pigmentation, and incidents of skin cancer involved in the manifestations of this disorder.

New prenatal diagnostics and genetic testing methods, genetic risk assessment for individuals, families, and communities, and novel genetic markers that may be used for developing new therapeutics for treating albinism are also discussed in detail. The book provides care management approaches that may be applied to instances of albinism in other regions, along with guiding principles for treating rare genetic disorders and stigmatized patient populations across the globe.

1. Introduction and historical background
2. Clinical features, types of albinism and natural history
3. Epidemiology of albinism
4. Medical aspects. Dermatology
5. Medical aspects. Ophthalmology
6. Psychosocial aspects of albinism
7. Molecular biology of albinism
8. Genetic Counselling
9. Genetic testing and prenatal diagnosis
10. Management and therapy
11. Conclusion

Subject Areas: Genetics [non-medical PSAK]

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