Akathisia and Restless Legs

A comprehensive, scientific and clinical account of akathisia and related syndromes, including Restless Legs Syndrome.

Perminder Sachdev (Author)

9780521031486, Cambridge University Press

Paperback / softback, published 2 November 2006

444 pages, 16 b/w illus. 51 tables
22.8 x 15.2 x 2.7 cm, 0.67 kg

'… diligently researched and lucidly written …' Psychological Medicine

This book reviews our knowledge of akathisia and related syndromes, including Restless Legs Syndrome, other forms of motor restlessness and neuroleptic-induced dysphoria and is a comprehensive account of these important, but insufficiently researched, syndromes. The main focus is on drug-induced akathisia and its various subtypes. The author explores its relationship to the restlessness caused by other neurological disorders, presents a synthesis of the pathophysiological mechanisms of akathisia and provides arguments for operational criteria for the research diagnosis of drug-induced akathisia. Strategies for the measurement of akathisia are discussed, as are treatment approaches and a fascinating appendix contains a translation of Hashovec's account of the first cases in the literature. As the first extended review of scientific and clinical aspects of akathisia and restlessness, this book will be much valued by psychiatrists, neurologists and other physicians seeking a better understanding of these disabling syndromes.

Foreword John M. Kane
Acknowledgements
Abbreviations
Part I. Introduction: 1. Akathisia: development of the concept
2. The anatomy of restlessness
3. Neuroleptic-induced dysphoria
Part II. Drug-Induced Akathisia: 4. The definition of drug-induced akathisia
5. Epidemiology
6. Clinical characteristics and diagnosis of acute akathisia
7. Clinical characteristics of tardive and chronic akathisia
8. Akathisia due to a general medical condition
9. Assessment and measurement of akathisia
10. Aetiology and pathogenesis of akathisia
11. Treatment of drug-induced akathisia
Part III. Restless Legs Syndrome: 12. Restless legs syndrome: clinical features and pathophysiology
13. Treatment of Restless legs syndrome
Part IV. Conclusions: 14. Summary and recommendations for future research
Appendices
References
Index.

Subject Areas: Neurology & clinical neurophysiology [MJN]