Advances in Structure and Activity Relationship of Coumarin Derivatives

Valuable focused work to support structural understanding and drug design in coumarin derivatives

Santhosh Penta (Edited by)

9780128037973

Paperback / softback, published 12 August 2015

190 pages
22.9 x 15.1 x 1.3 cm, 0.34 kg

Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity.

Chapter 1. Introduction to Coumarin and SAR Chapter 2. Anti-Microbial Agents Chapter 3. Anti-Tumor Agents Chapter 4. Neuroprotective Agents Chapter 5. Anti-depressing agents Chapter 6. Anti-inflammatory Agents Chapter 7. Anti-oxidant agents Chapter 8. Anti-coagulant Agents Chapter 9. Miscellaneous agents

Subject Areas: Organic chemistry [PNN], Pharmacology [MMG]