Advances in Planar Lipid Bilayers and Liposomes

A survey of recent theoretical and experimental results on lipid micro- and nanostructures presenting their potential use in applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products

Ales Iglic (Series edited by), Chandrashekhar V. Kulkarni (Series edited by), Michael Rappolt (Series edited by)

9780128021163

Hardback, published 23 March 2015

206 pages
22.9 x 15.1 x 2 cm, 0.47 kg

The Elsevier book-series "Advances in Planar Lipid Bilayers and Liposomes’ (APLBL) provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature and find their application in the formulation of biomimetic model membranes and in the design of artificial dispersion of liposomes. Moreover, lipids self-assemble into a wide range of other structures including micelles and the liquid crystalline hexagonal and cubic phases. Consensus has been reached that curved membrane phases do play an important role in nature as well, especially in dynamic processes such as vesicles fusion and cell communication. Self-assembled lipid structures have enormous potential as dynamic materials ranging from artificial lipid membranes to cell membranes, from biosensing to controlled drug delivery, from pharmaceutical formulations to novel food products to mention a few. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.

1. Development of Polymer/Nanodiamond Composite Coatings to Control Cell Adhesion, Growth and Functions

Milena Keremidarska, Kamelia Hristova, Todor Hikov, Ekaterina Radeva, Dimitar Mitev, Ivailo Tsvetanov, Radina Presker, Damjana Drobne, Barbara Drašler, Sara Novak, Veno Kononenko, Kristina Eleršic, Lilyana Pramatarova and Natalia Krasteva

2. Tethered Phospholipid Bilayer Membranes: An Interpretation of the Electrochemical Impedance Response

Gintaras Valincius and Mindaugas Mickevicius

3. Microscopy of Model Membranes: Understanding How Bcl-2 Proteins Mediate Apoptosis

Kushal Kumar Das, Joseph D. Unsay and Ana J. Garcia-Saez

4. Optical Microscopy of Giant Vesicles as a Tool to Reveal the Mechanism of Action of Antimicrobial Peptides and the Specific Case of Gomesin

Karin A. Riske

5. Steric Stabilisers for Cubic Phase Lyotropic Liquid Crystal Nanodispersions (Cubosomes) Josephine Y. T. Chong, Xavier Mulet, Ben J. Boyd and Calum J. Drummond

Subject Areas: Biotechnology [TCB], Lipids [PSBH], Biochemistry [PSB], Chemistry [PN], Biophysics [PHVN]