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Adenosine Receptors in Neurodegenerative Diseases
Comprehensive reference that details the function of adenosine receptors in neurodegeneration and translational approaches of adenosine-based therapies
David Blum (Edited by), Luisa V. Lopes (Edited by)
9780128037249
Hardback, published 31 March 2017
280 pages
22.9 x 15.1 x 2.2 cm, 0.59 kg
Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience.
Section I. Physiology 1. Physiology: Adenosine receptor biology in the CNS Michael Freissmuth and Karl-Norbert Klotz 2. Physiology: Adenosine signaling throughout development Stefania Zappettini and Christophe Bernard 3. Physiology: Influence of adenosine on synaptic excitability Detlev Boison, Raquel B. Dias, Traci Plumb, Sofia Cristóvão-Ferreira and Ana Sebastiao 4. Physiology: Regulation of synaptic transmission by adenosine at the neuromuscular junction Paula Pousinha and Joaquim A. Ribeiro 5. Physiology: Gene-regulation of adenosine A2A receptors in the central nervous system Marta Barrachina, Chien-Yu Lin and Yijuang Chern Section II. Pathology 6. Pathology: Sleep, adenosine, and neurodegeneration Theresa Bjorness and Robert W. Greene 7. Pathology: neuronal vs glial cell contribution to adenosine A2A receptor-induced neurodegeneration Antonella Ferrante, Maria Teresa Tebano, Alberto Martire, Maria Rosaria Domenici and Patrizia Popoli 8. Pathology: Adenosine and oxygen/glucose deprivation in the brain Felicita Pedata, Ilaria Dettori, Irene Fusco, Elisabetta Coppi, Anna Maria Pugliese and Alessia Melani 9. Pathology: Adenosine receptors and memory disorders Alexandre de Mendonca, David Blum and Jonathan D. Geiger 10. Pathology: Control of motor function by adenosine A2A receptors in Parkinson and Huntington disease Annalisa Pinna, Jadwiga Wardas, Maria Rosaria Domenici, Patrizia Popoli, Giovanni Cossu and Micaela Morelli 11. Pathology: Adenosine receptors oligomers in Parkinson disease Victor Fernández-Dueñas and Francisco Ciruela 12. Pathology: Adenosine control of striatal function – implications for the treatment of apathy in basal ganglia disorders Sergi Ferré
Subject Areas: Neurosciences [PSAN], Pathology [MMF], Physiology [MFG]
