a-Tertiary Amines en Route to Natural Products

Presents the multistep synthesis of natural products using schematic diagrams, along with discussions of key steps

Abdul Hameed (Author), Mariya Al-Rashida (Author), Muhammad Raza Shah (Author)

9780128222621, Elsevier Science

Paperback, published 21 January 2021

240 pages, Approx. 140 illustrations (140 in full color)
22.9 x 15.1 x 1.6 cm, 0.39 kg

a-Tertiary Amines en Route to Natural Products presents the multistep synthesis of natural products using schematic diagrams. This approach provides a quick-and-easy way to review and understand new and novel synthetic strategies to construct structural frameworks of natural products. The book covers the class of natural products bearing the a,a-disubstituted a-amino acid motif. Featured natural product molecules include Altemicidin, Amathaspiramide (A-F), Kaitocephalin, Lactacystin, Salinosporamide, Manzacidins (A,C), Neooxazolomycin, Sphingofungins (E,F), (1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid (ACPD), Total synthesis of cephalotaxine and related molecules, a-amino acids based natural products, a amino acid based natural products and Tetrodotoxin.

1. Introduction: a,a-Disubsituted a-Amino Acids 2. Altemicidin 3. Amathaspiramide(A-F) 4. Kaitocephalin 5. Lactacystin 6. Salinosporamide 7. Manzacidins (A, C) 8. Sphingofungins (E, F) Synthesis 9. ACPD ((1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid) 10. Miscellaneous alkaloids: (+)-LY35470, Piperidine based alkaloids and Tetrodotoxin 11. Introduction: a,a-Disubsituted a-Amino Acids 12. Altemicidin 13. Amathaspiramide(A-F) 14. Kaitocephalin 15. Lactacystin 16. Salinosporamide 17. Manzacidins (A, C) 18. Sphingofungins (E, F) Synthesis 19. ACPD ((1S,3R)-1-Aminocyclopentane-1,3-diarboxylic Acid) 20. Miscellaneous alkaloids: (+)-LY35470, Piperidine based alkaloids and Tetrodotoxin

Subject Areas: Organic chemistry [PNN]