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A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

Detailed information on the latest advances in drug carriers, inhibitor design, inhibition nature, and the impact of stem cells for tuberculosis therapy

Rajan Mariappan (Edited by)

9780128199855, Elsevier Science

Paperback, published 18 March 2021

326 pages, Approx. 200 illustrations
23.4 x 19 x 2.1 cm, 0.68 kg

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications.

This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine.

1. Basics of tuberculosis disease and Principles of treatment and their effects
2. The pulmonary administration route: Advantages and challenges
3. Alternative non-invasive routes of administration of nanomedicines against Tuberculosis
4. Approaches of designing nanocarriers for Tuberculosis drug delivery
5. Controlled Strategies towards the nanotherapy of tuberculosis
6. Tuberculosis disease targeted nanotherapy
7. pH, Thermo and stimuli responsive nanotherapy beside anti-tuberculosis drug delivery
8. Nanotheranostics management of Drug resistant tuberculosis
9. Nanomedicine for bone tuberculosis
10. Current approach of Stem Cell Medicine in Drug-Resistant Tuberculosis
11. Adjuvant nanoformulations for delivery of anti-tuberculosis vaccine patients
12. Sensors development for tuberculosis Detection
13. In-silico and computational approaches of inhibitor design
14. Inhibitors treatment against Tuberculosis treatment
15. Challenges and future perspectives

Subject Areas: Biotechnology [TCB], Pharmacology [MMG], Pharmaceutical industries [KNDP]

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