8-Membered Heterocycle Synthesis

Provides complete coverage of the latest developments in approaches to eight-membered heterocycle synthesis, including easy access to synthetic protocols

Navjeet Kaur (Author)

9780323956529, Elsevier Science

Paperback / softback, published 24 February 2023

564 pages
22.9 x 15.2 x 3.5 cm, 0.45 kg

8-Membered Heterocycle Synthesis focuses on both the new and established methods for the synthesis of various 8-membered heterocycles. 8-membered heterocyclic compounds act as target molecules for a wide range of synthetic studies and are present in a broad range of natural products, showing a wide variety of pharmaceutical and biological properties. Covering an important and rapidly growing branch of heterocyclic chemistry, this book brings together every protocol for the synthesis of 8-membered heterocycles in one place, allowing the reader to see all the possibilities for making a particular compound using one particular reagent. 

1. Synthesis of azocines
2. Synthesis of azocines by diene metathesis
3. Synthesis of azocines by ring-expansion
4. Synthesis of azocines and diazocines from amine containing alkenes and alkynes
5. Synthesis of diazocines
6. Synthesis of diazocines and oxocines by cyclization of dienes
7. Synthesis of diazocines and oxocines by ring-contraction and -expansion
8. Synthesis of azocines and oxocines by ring-closure of halo, amine and oxo compounds
9. Synthesis of oxocines
10. Synthesis of oxazocines
11. Synthesis of thiocines and thiazocines
References

Subject Areas: Biotechnology [TCB]