{"product_id":"wilson-disease-hardback-9780444636256","title":"Wilson Disease (Hardback) 9780444636256","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eWilson Disease\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003eOffers broad coverage of this devastating disease, with an emphasis on molecular pathology, diagnosis and treatment, and multiple patient populations\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eAnna Czlonkowska (Edited by), Michael Schilsky (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780444636256, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 16 May 2017\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e264 pages\u003cbr\u003e27.5 x 21.5 x 2.2 cm, 0.88 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eWilson Disease \u003c\/i\u003eprovides a comprehensive guide on this inherited genetic disorder that has devastating consequences for both the liver and neurologic\/psychiatric health. This disease is of increasing interest to neurologists, hepatologists, and geneticists, but when the disease is diagnosed early, it is treatable, with patients living normal lives. \u003c\/p\u003e  \u003cp\u003eThis volume describes the molecular pathophysiology of WD and the clinical and pathological effects of copper. Separate sections address both diagnosis and medical and surgical approaches to treatment. Both adult and pediatric perspectives on diagnosis and treatment are addressed, and a section on genetics highlights advances in molecular diagnostics. Patient support groups that can aid in coping with this disease are also discussed, as are animal models for those interested in basic research on cell biology, pathophysiology, and treatment. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e1. History of Wilson disease: a personal account\u003cbr\u003e\u003ci\u003eJ M. Walshe\u003cbr\u003e\u003c\/i\u003e2. Epidemiology and introduction to the clinical presentation of Wilson disease\u003cbr\u003e\u003ci\u003eChristine Lo and Oliver Bandmann \u003cbr\u003e\u003c\/i\u003e3. The Genetics of Wilson disease\u003cbr\u003e\u003ci\u003eSihoun Hahn\u003cbr\u003e\u003c\/i\u003e4. Genetic and environmental modifiers of Wilson disease\u003cbr\u003e\u003ci\u003eValentina Medici and Karl Heinz Weiss \u003cbr\u003e\u003c\/i\u003e5. Pathogenesis of Wilson disease\u003cbr\u003e\u003ci\u003ePetr Dusek, Radan Bruha and Ivo Florin Scheiber \u003cbr\u003e\u003c\/i\u003e6. Animal models of Wilson disease\u003cbr\u003e\u003ci\u003eDominik Huster and Valentina Medici \u003cbr\u003e\u003c\/i\u003e7. Wilson disease – liver pathology\u003cbr\u003e\u003ci\u003eMaciej Pronicki\u003cbr\u003e\u003c\/i\u003e8. Wilson disease – brain pathology\u003cbr\u003e\u003ci\u003eFrance Woimant, Aurelia Poujois and Jacqueline Mikol \u003cbr\u003e\u003c\/i\u003e9. Hepatic features of Wilson disease \u003cbr\u003e\u003ci\u003eMichael L. Schilsky, Aftab Ala and Salih Boga \u003cbr\u003e\u003c\/i\u003e10. Wilson disease: neurologic features\u003cbr\u003e\u003ci\u003eAnna Czlonkowska, Tomasz Litwin and Grzegorz Chabik \u003cbr\u003e\u003c\/i\u003e11. Cognitive and psychiatric symptoms in Wilson disease\u003cbr\u003e\u003ci\u003ePaula C. Zimbrean and Joanna Seniow \u003cbr\u003e\u003c\/i\u003e12. Wilson’s disease in children\u003cbr\u003e\u003ci\u003eEve A. Roberts and Piotr Socha \u003cbr\u003e\u003c\/i\u003e13. Other organ involvement and clinical aspects of Wilson disease\u003cbr\u003e\u003ci\u003eKarolina Dziezyc, Tomasz Litwin and Anna Czlonkowska \u003cbr\u003e\u003c\/i\u003e14. Diagnosis of Wilson disease\u003cbr\u003e\u003ci\u003ePeter Ferenci\u003cbr\u003e\u003c\/i\u003e15. Wilson disease - currently used anti-copper therapy\u003cbr\u003e\u003ci\u003eAnna Czlonkowska and Tomasz Litwin \u003cbr\u003e\u003c\/i\u003e16. Liver transplantation for Wilson disease  \u003cbr\u003e\u003ci\u003eMichael L. Schilsky\u003cbr\u003e\u003c\/i\u003e17. Wilson disease - symptomatic liver therapy \u003cbr\u003e\u003ci\u003eWolfgang Stremmel and Karl Heinz Weiss \u003cbr\u003e\u003c\/i\u003e18. Symptomatic treatment of neurologic symptoms in Wilson disease.\u003cbr\u003e\u003ci\u003eTomasz Litwin, Petr Dusek and Anna Czlonkowska \u003cbr\u003e\u003c\/i\u003e19. Novel perspectives on Wilson disease treatment\u003cbr\u003e\u003ci\u003eChristian Rupp, Wolfgang Stremmel and Karl Heinz Weiss \u003cbr\u003e\u003c\/i\u003e20. Patient support groups in the management of Wilson disease\u003cbr\u003e\u003ci\u003eMichael L. Schilsky and Mary L. Graper\u003c\/i\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Neurology \u0026amp; clinical neurophysiology [\u003ca title=\"See our other books on Neurology \u0026amp; clinical neurophysiology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Neurology%20\u0026amp;%20clinical%20neurophysiology%20%5BMJN%5D%22\"\u003eMJN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier","offers":[{"title":"Default Title","offer_id":46648844943640,"sku":"9780444636256","price":167.39,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780444636256_d2c0b3ce-4bd5-48c9-ba7b-1b220f5ed4db.jpg?v=1694987324","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/wilson-disease-hardback-9780444636256","provider":"Freshly Printed Books","version":"1.0","type":"link"}