{"product_id":"vaccine-development-and-manufacturing-hardback-9780470261941","title":"Vaccine Development and Manufacturing (Hardback) 9780470261941","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eVaccine Development and Manufacturing\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eEmily P. Wen (Edited by), Ronald Ellis (Edited by), Narahari S. Pujar (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470261941, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 20 January 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e456 pages\u003cbr\u003e24.3 x 16.3 x 2.8 cm, 0.753 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eVaccine Manufacturing and Production\u003c\/i\u003e is an invaluable reference on how to produce a vaccine - from beginning to end - addressing all classes of vaccines from a processing, production, and regulatory viewpoint. It will provide comprehensive information on the various fields involved in the production of vaccines, from fermentation, purification, formulation, to regulatory filing and facility designs. In recent years, there have been tremendous advances in all aspects of vaccine manufacturing. Improved technology and growth media have been developed for the production of cell culture with high cell density or fermentation. \u003ci\u003eVaccine Manufacturing and Production\u003c\/i\u003e will serve as a reference on all aspects of vaccine production by providing an in-depth description of the available technologies for making different types of vaccines and the current thinking in facility designs and supply issues. This book will provide insight to the issues scientists face when producing a vaccine, the steps that are involved, and will serve as a reference tool regarding state-of-the-art vaccine manufacturing technologies and facility set-up.\u003cbr\u003e \u003cbr\u003e Highlights include:\u003cbr\u003e \u003cbr\u003e \u003c\/p\u003e \u003cul\u003e \u003cli\u003eComprehensive coverage of vaccine production : from a process point of view- fermentation to purification to formulation developments; from a production point of view - from facility design to manufacturing; and from a regulatory point of view - requirements from government agencies\u003c\/li\u003e \u003cli\u003eAuthors from different major pharmaceutical and biotechnology companies\u003c\/li\u003e \u003cli\u003eDescribes the challenges and issues involved in vaccine production and manufacturing of the different classes of vaccines, an area not covered by other books currently on the market\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eAcknowledgments vii\u003c\/p\u003e \u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003e1 History of Vaccine Process Development 1\u003cbr\u003e\u003ci\u003eNarahari S. Pujar, Sangeetha L. Sagar, and Ann L. Lee\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 The Production of Plasmid DNA Vaccine in \u003ci\u003eEscherichia coli\u003c\/i\u003e: A Novel Bacterial-Based Vaccine Production Platform 25\u003cbr\u003e\u003ci\u003eMichel Chartrain\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Fungal Expression Systems for Vaccine Production 51\u003cbr\u003e\u003ci\u003eKarl Melber, Volker Jenzelewski, Roland Weyhenmeyer, and Zbigniew Janowicz\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Novel Expression Systems for Vaccine Production 81\u003cbr\u003e\u003ci\u003eShailaja Rabindran and Vidadi Yusibov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Viral Vaccines Purification 97\u003cbr\u003e\u003ci\u003eBernd Kalbfuss-Zimmermann and Udo Reichl\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Protein Subunit Vaccine Purification 181\u003cbr\u003e\u003ci\u003eYan-ping Yang and Tony D’Amore\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Conjugate Vaccine Production Technology 217\u003cbr\u003e\u003ci\u003eSudha Chennasamudram and Willie F. Vann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Stabilization and Formulation of Vaccines 237\u003cbr\u003e\u003ci\u003eTimothy S. Priddy and C. Russell Middaugh\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Lyophilization in Vaccine Processes 263\u003cbr\u003e\u003ci\u003eAlexis Wasserman, Ranjit Sarpal, and Bret R. Phillips\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Strategies for Heat-Stable Vaccines 287\u003cbr\u003e\u003ci\u003eSatoshi Ohtake, David Lechuga-Ballesteros, Vu Truong-Le, and Eric J. Patzer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Production and Characterization of Aluminum-Containing Adjuvants 319\u003cbr\u003e\u003ci\u003eStanley L. Hem and Cliff T. Johnston\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 The Biologics License Application (BLA) in Common Technical Document (CTD) Format 347\u003cbr\u003e\u003ci\u003eR.S. Robin Robinett\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 The Original New Drug Application (Investigational New Drug) 373\u003cbr\u003e\u003ci\u003eR.S. Robin Robinett\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Facility Design for Vaccine Manufacturing—Regulatory, Business, and Technical Considerations and A Risk-Based Design Approach 393\u003cbr\u003e\u003ci\u003eAnand Ekambaram and Abraham Shamir\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Vaccine Production Economics 413\u003cbr\u003e\u003ci\u003eAndrew Sinclair and Peter Latham\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 437\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52512234307864,"sku":"9780470261941","price":106.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470261941.jpg?v=1786616585","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/vaccine-development-and-manufacturing-hardback-9780470261941","provider":"Freshly Printed Books","version":"1.0","type":"link"}