{"product_id":"trends-in-drug-research-ii-hardback-9780444826336","title":"Trends in Drug Research II (Hardback) 9780444826336","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eTrends in Drug Research II\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eH. van der Goot (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780444826336, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 16 January 1998\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e246 pages\u003cbr\u003e24.1 x 18.3 x 2.1 cm, 0.56 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eThis volume of Pharmacochemistry Library comprises the text of invited lectures presented at the 11th Noordwijkerhout-Camerino Symposium \u003ci\u003eTrends in Drug Research\u003c\/i\u003e, held in Noordwijkerhout, The Netherlands, from 11-15 May 1997.\u003c\/p\u003e  \u003cp\u003eIn the programme attention has been given to the generation of new biological target systems and the generation of new lead molecules, with presentations on e.g. combinatorial chemistry, compound libraries, database search, high throughput screening and molecular biology.\u003c\/p\u003e  \u003cp\u003eOther topics discussed were the perspectives for new medicines for the gastro-intestinal tract, the major developments in the search for effective anti-HIV drugs and new aspects in synthetic approaches. In a special session three topics which currently draw much attention were discussed: How to deal with the major problem of resistance against antimirobial agents? Can the apoptosis mechanism be used as a drug target? Is the newly observed phenomenon of inverse agonism a general principle and has it consequences for drug development (and use?)\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eInsights into the structure and function of genetic disease genes from genome research and clues for drug therapy (P.L. Pearson). New Developments in synthetic medicinal chemistry (F. Gaultieri). New biocatalytic approaches for the synthesis of chiral drugs, intermediates, and substrates (K. Laumen \u003ci\u003eet al\u003c\/i\u003e.). Ligands for the 5-HT \u003ci\u003e2C\u003c\/i\u003e receptor as potential antidepressents and anxiolytics (D. Leysen, J. Kelder). 5-HT \u003ci\u003e1A\u003c\/i\u003e-affinity, activity and selectivity \u003ci\u003eversus\u003c\/i\u003e D\u003ci\u003e2\u003c\/i\u003e-receptors of flesinoxan and analogous (W. Kuipers). Pharmacokinetics and metabolism in drug development: current and future strategies (D.D. Breimer). Novel approaches towards anti-HIV chemotherapy (E. De Clercq). HBY 097 - a second-generation nonnucleoside inhibitor of the HIV-1 reverse transcriptase (J-P. Kleim). The HIV tat-TAR interaction, a novel target for drug discovery (J. Karn \u003ci\u003eet al\u003c\/i\u003e.). Diverse approaches to combinatorial library design (E.J. Martin \u003ci\u003eet al\u003c\/i\u003e.). Heterocyclic mixture- based combinatorial libraries: synthesis and analysis of composition (J.S. Kiely, Y. Pei). Chemistry and SAR of prokinetic motilides: non peptidic motilin receptor agonists (P.A. Lartey). Modulators of 5-HT functions in the treatment of gastrointestinal disorders (F.D. King \u003ci\u003eet al\u003c\/i\u003e.). The impact of robotics and novel assay technologies on lead discovery processes (J.G. Houston). Hot topics (P. Angeli). Inverse agonism at G protein-coupled receptors. Studies with wild type and mutated adrenergic and opioid receptors (G. Milligan). Antibiotic resistance - a view from the pharmaceutical industry (R. Bax).\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Pharmaceutical technology [\u003ca title=\"See our other books on Pharmaceutical technology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmaceutical%20technology%20%5BTDCW%5D%22\"\u003eTDCW\u003c\/a\u003e], Genetics [\u003ca title=\"See our other books on Genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetics%20%5Bnon-medical%5D%20%5BPSAK%5D%22\"\u003enon-medical PSAK\u003c\/a\u003e], Organic chemistry [\u003ca title=\"See our other books on Organic chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Organic%20chemistry%20%5BPNN%5D%22\"\u003ePNN\u003c\/a\u003e], Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":46651535294744,"sku":"9780444826336","price":136.79,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780444826336_2cb1709b-6608-400d-ad0e-a026cadba047.jpg?v=1694987409","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/trends-in-drug-research-ii-hardback-9780444826336","provider":"Freshly Printed Books","version":"1.0","type":"link"}