{"product_id":"transporters-in-drug-discovery-and-development-detailed-concepts-and-best-practice-hardback-9781907568213","title":"Transporters in Drug Discovery and Development; Detailed Concepts and Best Practice (Hardback) 9781907568213","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eTransporters in Drug Discovery and Development\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eDetailed Concepts and Best Practice\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003e\u003cp\u003eA comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development, with balanced coverage of molecular biology aspects and functional outcomes\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eYurong Lai (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781907568213, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 31 October 2013\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e780 pages\u003cbr\u003e23.3 x 15.6 x 4 cm, 1.23 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eWritten by a leading researcher in the field, \u003ci\u003eTransporters in Drug Discovery and Development \u003c\/i\u003eprovides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro\/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eMembrane transporters and the diseases corresponding to functional defects\u003cbr\u003e P-glycoprotein (P-gp\/MDR1)\/ABCB1\u003cbr\u003e Multidrug resistance- associated protein 2 (MRP2\/ABCC2)\u003cbr\u003e Breast cancer resistance protein (BCRP)\/ABCG2\u003cbr\u003e The bile salt export pump (BSEP\/ABCB11)\u003cbr\u003e Organic anion- transporting polypeptides (OATPs\/SLCOs)\u003cbr\u003e Organic anion, organic cation and zwitterion transporters of the SLC22 and SLC47 superfamily (OATs, OCTs, OCTNs and MATEs)\u003cbr\u003e Drug transporters in drug discovery and development\u003cbr\u003e Transporter study methodologies.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biochemistry [\u003ca title=\"See our other books on Biochemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biochemistry%20%5BPSB%5D%22\"\u003ePSB\u003c\/a\u003e], Pharmacology [\u003ca title=\"See our other books on Pharmacology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Pharmacology%20%5BMMG%5D%22\"\u003eMMG\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Woodhead Publishing","offers":[{"title":"Default Title","offer_id":46651780071704,"sku":"9781907568213","price":135.99,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9781907568213_70ed5486-f4d7-48db-8e4e-7d97312182d8.jpg?v=1696598735","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/transporters-in-drug-discovery-and-development-detailed-concepts-and-best-practice-hardback-9781907568213","provider":"Freshly Printed Books","version":"1.0","type":"link"}