{"product_id":"trace-quantitative-analysis-by-mass-spectrometry-hardback-9780470057711","title":"Trace Quantitative Analysis by Mass Spectrometry (Hardback) 9780470057711","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eTrace Quantitative Analysis by Mass Spectrometry\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert K. Boyd (Author), Cecilia Basic (Author), Robert A. Bethem (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470057711, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 18 April 2008\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e752 pages\u003cbr\u003e25.4 x 19.6 x 4.8 cm, 1.746 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"This work, well documented and easy to read, will without doubt delight teachers and researchers in analytical chemistry, permitting them to choose apparatus best suited to their analytical problems, to understand how to use them, and finally to put them to work in developing and validating quantitative methods in thev laboratory.\" (l'actualité chimique, October 2010)\"There are many textbooks on the general principles and applications of mass spectrometry, but none of them cover these topics in such detail as the present book. … A valuable contribution to the mass spectrometry textbooks that are currently available, and is useful for both the neophyte and the specialist.\" (\u003ci\u003eAnalytical and Bioanalytical Chemistry\u003c\/i\u003e, July 2009)  \u003cp\u003e\"I highly recommend this book … to all those readers of this journal involved in quantitative analysis … Boyd, Basic, and Bethem provided us with a wealth of easy accessible information on this subject.\" (\u003ci\u003eJournal of Statistical Software\u003c\/i\u003e, January 2009)\u003c\/p\u003e \u003cp\u003e\"\u003ci\u003eTrace Quantitative Analysis by Mass Spectrometry\u003c\/i\u003e is a wonderful book for beginner and intermediate students, analysts, and scientists keen on learning more about mass spectrometry. The authors' discussion of history and the evolution of relevant science make the text lively and engaging, no small achievement for a book about analytical science.\" (\u003ci\u003ePharmTech.com\u003c\/i\u003e, December 2, 2008)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eFundiert, verständlich, anwendungsorientiert: Im Lehrbuchstil verfasst, führt das Werk so in die Massenspektrometrie ein, dass seine Leser nach gründlicher Lektüre in der Lage sind, die hier vorgestellten Techniken - insbesondere moderne Massenspektrometer - im Labor einzusetzen.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cb\u003ePreface.\u003c\/b\u003e  \u003cp\u003e\u003cb\u003eAcknowledgements.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Measurement, Dimensions and Units.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.2 The International System of Units (SI).\u003c\/p\u003e \u003cp\u003e1.3 ‘Mass-to-Charge Ratio’ in Mass Spectrometry.\u003c\/p\u003e \u003cp\u003e1.4 Achievable Precision in Measurement of SI Base Quantities.\u003c\/p\u003e \u003cp\u003e1.5 Molecular Mass Limit for Trace Quantitation by Mass Spectrometry.\u003c\/p\u003e \u003cp\u003e1.6 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Tools of the Trade I. The Classical Tools.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.2 Analytical and Internal Standards: Reference Materials.\u003c\/p\u003e \u003cp\u003e2.3 The Analytical Balance.\u003c\/p\u003e \u003cp\u003e2.4 Measurement and Dispensing of Volume.\u003c\/p\u003e \u003cp\u003e2.5 Preparation of Solutions for Calibration.\u003c\/p\u003e \u003cp\u003e2.6 Introduction to Calibration Methods for Quantitative Analysis.\u003c\/p\u003e \u003cp\u003e2.7 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Tools of the Trade II. Theory of Chromatography.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 General Principles of Chemical Separations.\u003c\/p\u003e \u003cp\u003e3.3 Summary of Important Concepts.\u003c\/p\u003e \u003cp\u003e3.4 Plate Theory of Chromatography.\u003c\/p\u003e \u003cp\u003e3.5 Nonequilibrium Effects in Chromatography: the van Deemter Equation.\u003c\/p\u003e \u003cp\u003e3.6 Gradient Elution.\u003c\/p\u003e \u003cp\u003e3.7 Capillary Electrophoresis and Capillary Electrochromatography.\u003c\/p\u003e \u003cp\u003eAppendix 3.1 Derivation of the Plate Theory Equation for Chromatographic Elution.\u003c\/p\u003e \u003cp\u003eAppendix 3.2 Transformation of the Plate Theory Elution Equation from Poisson to Gaussian Form.\u003c\/p\u003e \u003cp\u003eAppendix 3.3 A Brief Introduction to Snyder’s Theory of Gradient Elution.\u003c\/p\u003e \u003cp\u003eList of Symbols Used in Chapter 3.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Tools of the Trade III. Separation Practicalities.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 The Analyte and the Matrix.\u003c\/p\u003e \u003cp\u003e4.3 Extraction and Clean-Up: Sample Preparation Methods.\u003c\/p\u003e \u003cp\u003e4.4 Chromatographic Practicalities.\u003c\/p\u003e \u003cp\u003e4.5 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003eAppendix 4.1 Responses of Chromatographic Detectors: Concentration vs Mass–Flux Dependence.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Tools of the Trade IV. Interfaces and Ion Sources for Chromatography–Mass Spectrometry.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Ion Sources that can Require a Discrete Interface Between Chromatograph and Source.\u003c\/p\u003e \u003cp\u003e5.3 Ion Sources not Requiring a Discrete Interface.\u003c\/p\u003e \u003cp\u003e5.4 Source–Analyzer Interfaces Based on Ion Mobility.\u003c\/p\u003e \u003cp\u003e5.5 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003e5.1 Appendix 5.1: Methods of Sample Preparation for Analysis by MALDI.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Tools of the Trade V. Mass Analyzers for Quantitation: Separation of Ions by \u003ci\u003em\u003c\/i\u003e\u003c\/b\u003e\/\u003cb\u003e\u003ci\u003ez\u003c\/i\u003e Values.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Mass Analyzer Operation Modes and Tandem Mass Spectrometry.\u003c\/p\u003e \u003cp\u003e6.3 Motion of Ions in Electric and Magnetic Fields.\u003c\/p\u003e \u003cp\u003e6.4 Mass Analyzers.\u003c\/p\u003e \u003cp\u003e6.5 Activation and Dissociation of Ions.\u003c\/p\u003e \u003cp\u003e6.6 Vacuum Systems.\u003c\/p\u003e \u003cp\u003e6.7 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003eAppendix 6.1 Interaction of Electric and Magnetic Fields with Charged Particles.\u003c\/p\u003e \u003cp\u003eAppendix 6.2 Leak Detection.\u003c\/p\u003e \u003cp\u003eAppendix 6.3 List of Symbols Used in Chapter 6.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Tools of the Trade VI. Ion Detection and Data Processing.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 Introduction.\u003c\/p\u003e \u003cp\u003e7.2 Faraday Cup Detectors.\u003c\/p\u003e \u003cp\u003e7.3 Electron Multipliers.\u003c\/p\u003e \u003cp\u003e7.4 Post-Detector Electronics.\u003c\/p\u003e \u003cp\u003e7.5 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Tools of the Trade VII: Statistics of Calibration, Measurement and Sampling.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction.\u003c\/p\u003e \u003cp\u003e8.2 Univariate Data: Tools and Tests for Determining Accuracy and Precision.\u003c\/p\u003e \u003cp\u003e8.3 Bivariate Data: Tools and Tests for Regression and Correlation. \u003c\/p\u003e \u003cp\u003e8.4 Limits of Detection and Quantitation.\u003c\/p\u003e \u003cp\u003e8.5 Calibration and Measurement: Systematic and Random Errors.\u003c\/p\u003e \u003cp\u003e8.6 Statistics of Sampling of Heterogeneous Matrices.\u003c\/p\u003e \u003cp\u003e8.7 Summary of Key Concepts.\u003c\/p\u003e \u003cp\u003eAppendix 8.1 A Brief Statistics Glossary.\u003c\/p\u003e \u003cp\u003eAppendix 8.2 Symbols Used in Discussion of Calibration Methods.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Method Development and Fitness for Purpose.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Introduction.\u003c\/p\u003e \u003cp\u003e9.2 Fitness for Purpose and Managing Uncertainty.\u003c\/p\u003e \u003cp\u003e9.3 Issues Between Analyst and Client: Examining What’s at Stake.\u003c\/p\u003e \u003cp\u003e9.4 Formulating a Strategy.\u003c\/p\u003e \u003cp\u003e9.5 Method Development.\u003c\/p\u003e \u003cp\u003e9.6 Matrix Effects.\u003c\/p\u003e \u003cp\u003e9.7 Contamination and Carryover.\u003c\/p\u003e \u003cp\u003e9.8 Establishing the Final Method.  \u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Method Validation and Sample Analysis in a Controlled Laboratory Environment.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Introduction.\u003c\/p\u003e \u003cp\u003e10.2 Method Validation.\u003c\/p\u003e \u003cp\u003e10.3 Conduct of the Validaton.\u003c\/p\u003e \u003cp\u003e10.4 Examples of Methods and Validations Fit for Purpose.\u003c\/p\u003e \u003cp\u003e10.5 Validated Sample Analysis.\u003c\/p\u003e \u003cp\u003e10.6 Documentation.\u003c\/p\u003e \u003cp\u003e10.7 Traceability.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Examples from the Literature.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Introduction.\u003c\/p\u003e \u003cp\u003e11.2 Food Contaminants.\u003c\/p\u003e \u003cp\u003e11.3 Anthropogenic Pollutants in Water.\u003c\/p\u003e \u003cp\u003e11.4 GC–MS Analyses of Persistent Environmental Pollutants.\u003c\/p\u003e \u003cp\u003e11.5 Bioanalytical Applications.\u003c\/p\u003e \u003cp\u003e11.6 Quantitative Proteomics.\u003c\/p\u003e \u003cp\u003e11.7 Analysis of Endogenous Analytes.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eEpilog.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eReferences.\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eIndex.\u003c\/b\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52256844153112,"sku":"9780470057711","price":94.39,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470057711.jpg?v=1781275210","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/trace-quantitative-analysis-by-mass-spectrometry-hardback-9780470057711","provider":"Freshly Printed Books","version":"1.0","type":"link"}