{"product_id":"topological-data-analysis-for-genomics-and-evolution-topology-in-biology-hardback-9781107159549","title":"Topological Data Analysis for Genomics and Evolution; Topology in Biology (Hardback) 9781107159549","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eTopological Data Analysis for Genomics and Evolution\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eTopology in Biology\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eAn introduction to geometric and topological methods to analyze large scale biological data; includes statistics and genomic applications.\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRaul Rabadan (Author), Andrew J. Blumberg (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781107159549, Cambridge University Press\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 19 December 2019\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e324 pages, 277 colour illus.\u003cbr\u003e25.2 x 17.8 x 2.8 cm, 1.12 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e'… has been a useful strategy, it is ill-equipped to deal with the very high dimensionality of genomic data. The book will be of interest to biologists and mathematicians ranging from advanced undergraduates to experienced researchers seeking to add new analytic strategies in their work, or to establish collaborations across disciplines.' D. P. Genereux, Choice\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eBiology has entered the age of Big Data. A technical revolution has transformed the field, and extracting meaningful information from large biological data sets is now a central methodological challenge. Algebraic topology is a well-established branch of pure mathematics that studies qualitative descriptors of the shape of geometric objects. It aims to reduce comparisons of shape to a comparison of algebraic invariants, such as numbers, which are typically easier to work with. Topological data analysis is a rapidly developing subfield that leverages the tools of algebraic topology to provide robust multiscale analysis of data sets. This book introduces the central ideas and techniques of topological data analysis and its specific applications to biology, including the evolution of viruses, bacteria and humans, genomics of cancer, and single cell characterization of developmental processes. Bridging two disciplines, the book is for researchers and graduate students in genomics and evolutionary biology as well as mathematicians interested in applied topology.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eIntroduction\u003cbr\u003e Part I. Topological Data Analysis: 1. Basic notions of algebraic topology\u003cbr\u003e 2. Topological data analysis\u003cbr\u003e 3. Statistics and topological inference\u003cbr\u003e 4. Manifold learning and metric geometry\u003cbr\u003e Part II. Biological Applications: 5. Evolution, trees, and beyond\u003cbr\u003e 6. Cancer genomics\u003cbr\u003e 7. Single cell expression data\u003cbr\u003e 8. Three dimensional structure of DNA\u003cbr\u003e 9. Topological data analysis beyond genomics\u003cbr\u003e 10. Conclusions.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Genetics [\u003ca title=\"See our other books on Genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetics%20%5Bnon-medical%5D%20%5BPSAK%5D%22\"\u003enon-medical PSAK\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Cambridge University Press","offers":[{"title":"Default Title","offer_id":45978348585240,"sku":"9781107159549","price":41.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9781107159549i_e0f71e20-9aab-47f0-87e6-46a743e787d2.jpg?v=1691362462","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/topological-data-analysis-for-genomics-and-evolution-topology-in-biology-hardback-9781107159549","provider":"Freshly Printed Books","version":"1.0","type":"link"}