{"product_id":"theoretical-biochemistry-processes-and-properties-of-biological-systems-hardback-9780444502926","title":"Theoretical Biochemistry; Processes and Properties of Biological Systems (Hardback) 9780444502926","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eTheoretical Biochemistry\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eProcesses and Properties of Biological Systems\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eLeif A. Eriksson (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780444502926, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 19 February 2001\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e720 pages\u003cbr\u003e24.1 x 15.9 x 3.8 cm, 1.43 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003eA.S. Edison, University of Florida\"Researchers working on any of the applications covered in the book will find very stimulating chapters that do a fine job of demonstrating the power of combining theory with experiment.\" \u003cb\u003e--Journal of the American Chemical Society, 2002\u003c\/b\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eTheoretical chemistry has been an area of tremendous expansion and development over the past decade; from an approach where we were able to treat only a few atoms quantum mechanically or make fairly crude molecular dynamics simulations, into a discipline with an accuracy and predictive power that has rendered it an essential complementary tool to experiment in basically all areas of science. \u003cbr\u003e\u003cbr\u003e This volume gives a flavour of the types of problems in biochemistry that theoretical calculations can solve at present, and illustrates the tremendous predictive power these approaches possess.\u003cbr\u003e\u003cbr\u003e A wide range of computational approaches, from classical MD and Monte Carlo methods, via semi-empirical and DFT approaches on isolated model systems, to Car-Parinello QM-MD and novel hybrid QM\/MM studies are covered. The systems investigated also cover a broad range; from membrane-bound proteins to various types of enzymatic reactions as well as inhibitor studies, cofactor properties, solvent effects, transcription and radiation damage to DNA.\u003cbr\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eThe structure and function of blue copper proteins, (U. Ryde \u003ci\u003eet al.\u003c\/i\u003e).  Myoglobin (D. Karancsi-Menh\u0026amp;aacute\u003cbr\u003erd \u003ci\u003eet al.\u003c\/i\u003e).  Mechanisms for enzymatic reaction involviing formation or cleavage of O-O bonds (P.E.M. Siegbahn \u003ci\u003eet al.\u003c\/i\u003e).  Catalytic reactions of radical enzymes (F Himo, L.A. Eriksson).  Theoretical studies of coenzyme B12-dependant carbon-skeleton rearrangements (D.M. Smith \u003ci\u003eet al.\u003c\/i\u003e).  Simulations of enzymatic systems: perspectives form Car-Parinello molecular dynamics simulations(P. Carloni, U. Rothlisberger).  Computational enzymology: protein tyrosine phospatase reactions (K. Kolmodoin \u003ci\u003eet al.\u003c\/i\u003e).  Monte Carlo simulations of HIV-1 protease binding dynamics and thermodynamics with ensembles of protein conformations: incorporating protein flexibility in decipherine mechanisms of molecular recognition (G.M. Verkhivker \u003ci\u003eet al.\u003c\/i\u003e).  Modelling G-protein coupled receptors (C. Higgs, C.A. Reynolds).  Protein-DNA interactions in the initiation of transcription: the role of flexibility and dynamics of the TATA recognition sequence and the TATA box binding protein (N. Pastor, H. Weinstein).  A multi-component model for radiation damage to DNA from its components (S.D. Wetmore \u003ci\u003eet al.\u003c\/i\u003e.).  New computational strategies for the quantum mechanical study of biological systems in condensed phases (C. Adamo \u003ci\u003eet al.\u003c\/i\u003e).  Modelling enzyme-ligand interactions (M.J. Ramos \u003ci\u003eet al.\u003c\/i\u003e).  The QM\/CM approach to enzymatic reactions (A.J. Mulholland).  Quinones and quinoidal radicals in photosynthesis (R.A. Wheeler).  Author index.  Subject index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biochemistry [\u003ca title=\"See our other books on Biochemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biochemistry%20%5BPSB%5D%22\"\u003ePSB\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":46649077727512,"sku":"9780444502926","price":242.29,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780444502926.jpg?v=1694979911","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/theoretical-biochemistry-processes-and-properties-of-biological-systems-hardback-9780444502926","provider":"Freshly Printed Books","version":"1.0","type":"link"}