{"product_id":"the-organic-chemistry-of-drug-synthesis-volume-7-hardback-9780470107508","title":"The Organic Chemistry of Drug Synthesis, Volume 7 (Hardback) 9780470107508","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eThe Organic Chemistry of Drug Synthesis, Volume 7\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eDaniel Lednicer (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470107508, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 20 November 2007\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e288 pages\u003cbr\u003e23.6 x 15.9 x 1.9 cm, 0.508 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"The book is up-to-date with regard to the drugs presented and has the potential to be a good resources for experienced researchers in drug design…\" (\u003ci\u003eJournal of the American Chemical Society\u003c\/i\u003e, March 12, 2008)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cb\u003eThe classic reference on the synthesis of medicinal agents -- now completely updated\u003c\/b\u003e\u003cbr\u003e\u003cbr\u003eThe seventh volume in the definitive series that provides a quick yet thorough overview of the synthetic routes used to access specific classesof therapeutic agents, this volume covers approximately 220 new non-proprietary drug entities introduced since the publication of \u003ci\u003eVolume 6\u003c\/i\u003e. Many of these compounds represent novel structural types firstidentified by sophisticated new cell-based assays. Specifically, a significant number of new antineoplastic and antiviral agents are covered.\u003cbr\u003e\u003cbr\u003eAs in the previous volumes, materials are organized by chemical class and syntheses originate with available starting materials. Organized to make the information accessible, this resource covers disease state, rationale for method of drug therapy, and the biological activities of each compound and preparation. \u003ci\u003eThe Organic Chemistry of Drug Synthesis, Volume 7\u003c\/i\u003e is a hands-on reference for medicinal and organic chemists, and a great resource for graduate and advanced undergraduate students in organic and medicinal chemistry.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Open-Chain Compounds 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Peptidomimetic Compounds 2\u003c\/p\u003e \u003cp\u003eA. Antiviral Protease Inhibitors 2\u003c\/p\u003e \u003cp\u003e1. Human Immunodeficiency Virus 2\u003c\/p\u003e \u003cp\u003e2. Human Rhinovirus 9\u003c\/p\u003e \u003cp\u003e2. Miscellaneous Peptidomimetic Compounds 11\u003c\/p\u003e \u003cp\u003eReferences 19\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Alicyclic Compounds 21\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Monocyclic Compounds 21\u003c\/p\u003e \u003cp\u003eA. Prostaglandins 21\u003c\/p\u003e \u003cp\u003eB. Antiviral Agents 25\u003c\/p\u003e \u003cp\u003eC. Miscellaneous Monocyclic Compounds 29\u003c\/p\u003e \u003cp\u003e2. Polycyclic Compounds: Steroids 31\u003c\/p\u003e \u003cp\u003eA. 19-Nor Steroids 31\u003c\/p\u003e \u003cp\u003eB. Corticosteroid Related Compounds 34\u003c\/p\u003e \u003cp\u003e3. Polycyclic Compounds 38\u003c\/p\u003e \u003cp\u003eReferences 40\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Monocyclic Aromatic Compounds 43\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Arylcarbonyl Derivatives 43\u003c\/p\u003e \u003cp\u003e2. Biphenyls 47\u003c\/p\u003e \u003cp\u003e3. Compounds Related to Aniline 50\u003c\/p\u003e \u003cp\u003e4. Compounds Related to Arylsulfonic Acids 53\u003c\/p\u003e \u003cp\u003e5. Diarylmethanes 58\u003c\/p\u003e \u003cp\u003e6. Miscellaneous Monocyclic Aromatic Compounds 60\u003c\/p\u003e \u003cp\u003eReferences 67\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Carbocyclic Compounds Fused to a Benzene Ring 69\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Indenes 69\u003c\/p\u003e \u003cp\u003e2. Naphthalenes 73\u003c\/p\u003e \u003cp\u003e3. Tetrahydronaphthalenes 74\u003c\/p\u003e \u003cp\u003e4. Other benzofused carbocyclic compounds 79\u003c\/p\u003e \u003cp\u003eReferences 81\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Five-Membered Heterocycles 83\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Compounds with One Heteroatom 83\u003c\/p\u003e \u003cp\u003e2. Compounds with Two Heteroatoms 91\u003c\/p\u003e \u003cp\u003eA. Oxazole and Isoxazoles 91\u003c\/p\u003e \u003cp\u003eB. Imidazoles and a Pyrrazole 94\u003c\/p\u003e \u003cp\u003eC. Thiazoles 99\u003c\/p\u003e \u003cp\u003eD. Triazoles 103\u003c\/p\u003e \u003cp\u003eE. Tetrazoles 109\u003c\/p\u003e \u003cp\u003eReferences 112\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Six-Membered Heterocycles 115\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Compounds with One Heteroatom 115\u003c\/p\u003e \u003cp\u003eA. Pyridines 115\u003c\/p\u003e \u003cp\u003eB. Reduced Pyridines 117\u003c\/p\u003e \u003cp\u003eC. Miscellaneous 119\u003c\/p\u003e \u003cp\u003e2. Compounds with Two Heteroatoms 121\u003c\/p\u003e \u003cp\u003eA. Pyrimidines 121\u003c\/p\u003e \u003cp\u003eB. Miscellaneous Six-Membered Heterocycles 133\u003c\/p\u003e \u003cp\u003eReferences 136\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Five-Membered Heterocycles Fused to One Benzene Ring 139\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Compounds with One Heteroatom 139\u003c\/p\u003e \u003cp\u003eA. Benzofurans 139\u003c\/p\u003e \u003cp\u003eB. Indoles 141\u003c\/p\u003e \u003cp\u003eC. Indolones 148\u003c\/p\u003e \u003cp\u003eD. Miscellaneous Compounds with One Heteroatom 153\u003c\/p\u003e \u003cp\u003e2. Five-Membered Rings with Two Heterocyclic Atoms 156\u003c\/p\u003e \u003cp\u003eA. Benzimidazoles 156\u003c\/p\u003e \u003cp\u003eB. Miscellaneous Compounds 158\u003c\/p\u003e \u003cp\u003eReferences 160\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Six-Membered Heterocycles Fused to One Benzene Ring 163\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Compounds with One Heteroatom 163\u003c\/p\u003e \u003cp\u003eA. Benzopyrans 163\u003c\/p\u003e \u003cp\u003eB. Quinolines and Their Derivatives 167\u003c\/p\u003e \u003cp\u003eC. Quinolone Antibacterial Agents 172\u003c\/p\u003e \u003cp\u003e2. Compounds with Two Heteroatoms 176\u003c\/p\u003e \u003cp\u003eA. Benzoxazines 176\u003c\/p\u003e \u003cp\u003eB. Quinazolines 178\u003c\/p\u003e \u003cp\u003eC. Miscellaneous Benzo-Fused Heterocycles 184\u003c\/p\u003e \u003cp\u003eReferences 186\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Bicyclic Fused Heterocycles 189\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Compounds with Five-Membered Rings Fused to Six-Membered Rings 189\u003c\/p\u003e \u003cp\u003eA. Compounds with Two Heteroatoms 189\u003c\/p\u003e \u003cp\u003eB. Compounds with Three Heteroatoms 191\u003c\/p\u003e \u003cp\u003eC. Compounds with Four Heteroatoms 195\u003c\/p\u003e \u003cp\u003e2. Compounds with Two Fused Six-Membered Rings 208\u003c\/p\u003e \u003cp\u003e3. Miscellaneous Compounds with Two Fused Heterocyclic Rings: Beta Lactams 213\u003c\/p\u003e \u003cp\u003eReferences 215\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Polycyclic Fused Heterocycles 217\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1. Compounds with Three Fused Rings 217\u003c\/p\u003e \u003cp\u003e2. Compounds with Four Fused Rings 228\u003c\/p\u003e \u003cp\u003e3. Compounds with Five or More Fused Rings: Camptothecins 230\u003c\/p\u003e \u003cp\u003eReferences 232\u003c\/p\u003e \u003cp\u003eSubject Index 233\u003c\/p\u003e \u003cp\u003eCross Index of Biological Activity 241\u003c\/p\u003e \u003cp\u003eCumulative Index 245\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Interscience","offers":[{"title":"Brand New","offer_id":52257071366424,"sku":"9780470107508","price":110.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470107508.jpg?v=1781276280","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/the-organic-chemistry-of-drug-synthesis-volume-7-hardback-9780470107508","provider":"Freshly Printed Books","version":"1.0","type":"link"}