{"product_id":"the-oncogene-and-tumour-suppressor-gene-factsbook-paperback-9780123445483","title":"The Oncogene and Tumour Suppressor Gene Factsbook (Paperback \/ softback) 9780123445483","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eThe Oncogene and Tumour Suppressor Gene Factsbook\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobin Hesketh (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780123445483, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 11 July 1997\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e616 pages\u003cbr\u003e22.9 x 15.1 x 3.8 cm, 0.98 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\"Within minutes of receiving my review copy of \u003ci\u003eThe Oncogene FactsBook\u003c\/i\u003e I discovered just how useful it could be... I could have found the information I needed in a matter of seconds. There is no doubt that every lab working on oncogenes or growth control should have a copy of this book for reference.\" \u003cb\u003e--TRENDS IN BIOCHEMICAL SCIENCES\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003ePraise for the First Edition: \"The introductory chapters on genes and the processes involved in cancer development are very good for undergraduate teaching.\" \u003cb\u003e--MOLECULAR MEDICINE TODAY\u003c\/b\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eThe Second Edition of \u003ci\u003eThe Oncogene and Tumour Suppressor Gene FactsBook\u003c\/i\u003e has been completely revised, updated, and expanded by 60%. The book contains more than 80 entries on oncogenes including \u003ci\u003eJUN, MYC\u003c\/i\u003e, and \u003ci\u003eRAS\u003c\/i\u003e, as well as DNA tumour viruses, tumour suppressor genes, including p53, retinoblastoma, BRCA1, BRCA2, VHL, F2FL, and essential material on angiogenesis and metastasis, apoptosis, cell cycle control, and gene therapy.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cb\u003eThe Introductory Chapters:\u003c\/b\u003e\u003cbr\u003eIntroduction: Identification of Oncogenes.\u003cbr\u003eOncogene Activation in Humans.\u003cbr\u003eProliferation Control Pathways: Oncoprotein Function.\u003cbr\u003eGrowth Factor-Related Proteins.\u003cbr\u003e\u003ci\u003eSRC. RAS\u003c\/i\u003e and \u003ci\u003eRAF\u003c\/i\u003e.\u003cbr\u003eNuclear Oncoproteins.\u003cbr\u003e\u003ci\u003eETS. FOS\u003c\/i\u003e and \u003ci\u003eJUN. MYB. MYC. REL. ERBA\u003c\/i\u003e.\u003cbr\u003eTumour Suppressor Genes: \u003ci\u003eRB1. P53\u003c\/i\u003e.\u003cbr\u003eOther Major Tumour Suppressor Genes.\u003cbr\u003e\u003ci\u003eAPC. BRCA1. NF1. VHL. WT1\u003c\/i\u003e.\u003cbr\u003eCell Cycle Control: Cyclin-Dependent Kinase Inhibitors (\u003ci\u003eCDKIs\u003c\/i\u003e).\u003cbr\u003eApoptosis: Tumour Suppressor Genes and Apoptosis.\u003cbr\u003eDNA Repair.\u003cbr\u003eAngiogenesis and Metastasis: Angiogenesis.\u003cbr\u003eAngiogenic Promoters.\u003cbr\u003eAngiogenic Inhibitors.\u003cbr\u003eMetastasis: Correlations with Gene Expression.\u003cbr\u003eCadherins.\u003cbr\u003eThe Immunoglobulin Superfamily (IgSF), Neural Cell-Adhesion Molecule (\u003ci\u003eNCAM\u003c\/i\u003e).\u003cbr\u003eIntegrins.\u003cbr\u003e\u003ci\u003eCD44\u003c\/i\u003e.\u003cbr\u003eMatrix Metalloproteinases (MMPS).\u003cbr\u003eTissue Inhibitors of Metalloproteinases (TIMPs).\u003cbr\u003eCysteine and Aspartic Proteinases and Heparanase.\u003cbr\u003eNME1 and NME2.\u003cbr\u003eThe Multi-step Nature of Cancer: Cervical Carcinoma.\u003cbr\u003eColorectal Carcinoma.\u003cbr\u003eBreast Carcinoma.\u003cbr\u003eProstate Carcinoma.\u003cbr\u003eRenal Cell Carcinoma.\u003cbr\u003eLung Carcinoma.\u003cbr\u003eLymphomas.\u003cbr\u003eChronic Myeloid Leukemia.\u003cbr\u003eGene Therapy for Cancer: Nucleotide Sequence-Targeted Strategies.\u003cbr\u003eTumour Suppressor Gene Therapy.\u003cbr\u003eCytokine Gene Therapy and Tumour Vaccination.\u003cbr\u003eVirally Directed Enzyme Prodrug Therapy (VDEPT).\u003cbr\u003eAntibody-directed Therapy.\u003cbr\u003e\u003cb\u003eTables:\u003c\/b\u003e\u003cbr\u003eOncogenes Transduced by Retroviruses.\u003cbr\u003eOncogenes Activated by Retroviral Insertion.\u003cbr\u003eOncogenes at Chromosomal Translocations.\u003cbr\u003eTumour Suppressor Genes Detected in Human Tumours.\u003cbr\u003eFunctions of Oncoproteins.\u003cbr\u003eChromosome Locations of Human Proto-Oncogenes and Tumour Suppressor Genes.\u003cbr\u003e\u003cb\u003eThe Oncogenes:\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eABL. AKT1\u003c\/i\u003e and \u003ci\u003eAKT2. BCL2. BCL3. BCR. CBL. CDK4. CRK. CSFIR\/FMS. D Cyclins. DBL. EGFR\/ErbB. ELK1. EPH. ERG. ETS1\u003c\/i\u003e and \u003ci\u003eETS2. FGR. FLII. FOS. FOSB. FPS\/FES. FRA1\u003c\/i\u003e and \u003ci\u003eFRA2. FYN. HCK. HER2\/ErbB-2\/Neu. HER3\/ErbB-3. HER4\/ErbB-4. HSTF1\/HST2. INT2. JUN. JUNB. JUND. KIT. LCK. LYN. MAS. MAX. MET. Mil. MOS. MYB. MYC. PDGF\/Sis. PIM1. RAF. RAS. REL. RET. ROS1. SEA. SKI. SRC. TAL1. THRA\/ErbA-1\u003c\/i\u003e and \u003ci\u003eTHRA2\/ErbA-2. TIAM1. TRK. VAV. WNT1. WNT2\u003c\/i\u003e and \u003ci\u003eWNT3. YES1\u003c\/i\u003e.\u003cbr\u003e\u003cb\u003eTumour Suppressor Genes:\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eAPC\u003c\/i\u003e and \u003ci\u003eMCC. BRCA1\u003c\/i\u003e and \u003ci\u003eBRCA2. DCC. DPC4. E2F1. E-cadherin\/CDH1. MSH2. MSH3. MSH6\/GTBP \u003c\/i\u003eand \u003ci\u003eMLHL. NF1\u003c\/i\u003e and \u003ci\u003eNF2. P53, PTC\u003c\/i\u003e.\u003cbr\u003e\u003ci\u003eThe Retinoblastoma Gene (RB1). TGFBR1\u003c\/i\u003e and \u003ci\u003eTGFBR2. VHL; WT1\u003c\/i\u003e.\u003cbr\u003e\u003cb\u003eCyclin-dependent Kinase Inhibitors:\u003c\/b\u003e\u003cbr\u003e\u003ci\u003eINK4A\/MTS1\/MTS2\/CDK41\/CDKN2. INK4B\/MTS2.\u003cbr\u003eINK4C\u003c\/i\u003e and \u003ci\u003eINK4D. KIP1. KIP2. WAF1\u003c\/i\u003e.\u003cbr\u003e\u003cb\u003eDNA Tumour Viruses:\u003c\/b\u003e\u003cbr\u003eHuman Papillomaviruses.\u003cbr\u003eEpstein-Barr Virus.\u003cbr\u003eSubject Index.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Genetics [\u003ca title=\"See our other books on Genetics\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Genetics%20%5Bnon-medical%5D%20%5BPSAK%5D%22\"\u003enon-medical PSAK\u003c\/a\u003e], Oncology [\u003ca title=\"See our other books on Oncology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Oncology%20%5BMJCL%5D%22\"\u003eMJCL\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46649201721624,"sku":"9780123445483","price":45.66,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780123445483_a0d392f1-ab5b-427a-a143-3ce8a2f0f785.jpg?v=1695006757","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/the-oncogene-and-tumour-suppressor-gene-factsbook-paperback-9780123445483","provider":"Freshly Printed Books","version":"1.0","type":"link"}