{"product_id":"the-glutamate-synapse-as-a-therapeutic-target-hardback-9780444827548","title":"The Glutamate Synapse as a Therapeutic Target (Hardback) 9780444827548","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eThe Glutamate Synapse as a Therapeutic Target\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eO.P. Ottersen (Volume editor), I.A. Langmoen (Volume editor), L. Gjerstad (Volume editor)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780444827548, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 9 November 1998\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e0 pages\u003cbr\u003e22.9 x 15.2 x 1.3 cm, 1.43 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eThis volume provides a comprehensive update on basic glutamate research, from a clinical perspective. Thus, emphasis is placed on how the different molecular players at the glutamate synapse interact to produce a postsynaptic response, how synaptic transmission is perturbed in epilepsy and other pathological conditions, and how glutamate may acquire toxic properties and lead to acute or chronic neurodegeneration. Promising targets for therapeutic strategies are discussed.\u003cp\u003e\u003cbr\u003eA coherent picture is provided of the glutamate synapse and its molecular organization. The book therefore deals with each step in the signal process, from synthesis and vesicular uptake of glutamate to its clearance following receptor activation.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eI. Glutamate Release and Transport.\u003cbr\u003eII. Glutamate Synthesis and Translocation to Vesicles. \u003cbr\u003eIII. Glutamate Receptors. \u003cbr\u003eIV. Glutamate Toxicity and Cell Death in the Cental Nervous System. \u003cbr\u003eV. Conditions of Perturbed Glutamatergic Transmission.\u003cbr\u003e VI. Perspectives.\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Neurosciences [\u003ca title=\"See our other books on Neurosciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Neurosciences%20%5BPSAN%5D%22\"\u003ePSAN\u003c\/a\u003e], Neurosurgery [\u003ca title=\"See our other books on Neurosurgery\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Neurosurgery%20%5BMNN%5D%22\"\u003eMNN\u003c\/a\u003e], Neurology \u0026amp; clinical neurophysiology [\u003ca title=\"See our other books on Neurology \u0026amp; clinical neurophysiology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Neurology%20\u0026amp;%20clinical%20neurophysiology%20%5BMJN%5D%22\"\u003eMJN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier Science","offers":[{"title":"Default Title","offer_id":46651523825944,"sku":"9780444827548","price":156.39,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780444827548.jpg?v=1694113713","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/the-glutamate-synapse-as-a-therapeutic-target-hardback-9780444827548","provider":"Freshly Printed Books","version":"1.0","type":"link"}