{"product_id":"stem-cells-nuclear-reprogramming-and-therapeutic-applications-hardback-9780470091432","title":"Stem Cells; Nuclear Reprogramming and Therapeutic Applications (Hardback) 9780470091432","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eStem Cells\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eNuclear Reprogramming and Therapeutic Applications\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eGregory R. Bock (Edited by), Novartis (Author), Jamie A. Goode (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470091432, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 18 March 2005\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e232 pages\u003cbr\u003e23.4 x 15.4 x 1.8 cm, 0.539 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"...this book provides: a comprehensive overview of current issues in stem cell research, with contributions from leading figures in the field...\" (\u003ci\u003eBritish Society of Cell Biology\u003c\/i\u003e, January 2006)  \u003cp\u003e\"This compact book is easy to read…[discussions] provide insights into the practice of science as a deeply human enterprise. I learned a great deal.\" (\u003ci\u003eDoody's Health Services\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e‘This book is an essential purchase for all those engaged in stem cell research, whether in the laboratory or the clinic.’ (\u003ci\u003eAnticancer Research\u003c\/i\u003e, 2007)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eUnderstanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series features animated discussion from the world’s experts in this topic on the important ethical issues that are raised by research on stem cells. They review the various regulatory regimes, which apply in different countries – a key factor in determining where future stem cell research is carried out. \u003cp\u003ePotential clinical applications covered in the book include the production of cardiomyocytes to replace damaged heart tissue, the production of insulin-producing cells for patients with diabetes, and the generation of neurons for the treatment of patients with Parkinson’s disease or spinal cord injury. Particular attention is paid to the factors that maintain stem cells in a pluripotent state or which drive them to create differentiated and lineage-committed cells \u003ci\u003ein vitro\u003c\/i\u003e and \u003ci\u003ein vivo\u003c\/i\u003e.  Nuclear reprogramming, the process by which a nucleus acquires developmental potential, is covered here as well. It is relevant to stem cell research generally, and also to research on the cloning of animals by nuclear transfer. \u003c\/p\u003e \u003cp\u003eThis book is an essential purchase for all those engaged in stem cell research, whether in the laboratory, the clinic or the regulatory authorities.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eFrom the reviews:\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\"...this book provides: a comprehensive overview of current issues in stem cell research, with contributions from leading figures...\"\u003cbr\u003e—\u003ci\u003eBRITISH SOCIETY OF CELL BIOLOGY\u003c\/i\u003e\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eChair's Introduction \u003ci\u003e(John Gearhart).\u003c\/i\u003e  \u003cp\u003eWhat is a stem cell ?  Discussion \u003ci\u003e(Davor Solter).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eBone-marrow derived hepatocytes - Discussion \u003ci\u003e(Markus Grompe).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eNormal and neoplastic stem cells - Discussion \u003ci\u003e(Irvin L. Weissman).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eMultipotent adult progenitor cells: an update - Discussion \u003ci\u003e(Catherine A. Verfaillie).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eNeural progenitor cells of the adult brain - Discussion \u003ci\u003e(Steven A. Goldman and Fraser Sim).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eStem cells in the brain - General Discussion I.\u003c\/p\u003e \u003cp\u003eEmbryonic stem cells: a perspective - Discussion \u003ci\u003e(Martin Evans).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eNuclear cloning, epigenetic reprogramming and cellular differentiation - Discussion \u003ci\u003e(Rudolf Jaenisch, Konrad Hochedlinger and Kevin Eggan).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eGeneral Discussion II.\u003c\/p\u003e \u003cp\u003eNuclear reprogramming by xenopus oocytes - Discussion \u003ci\u003e(J.B. Gordon, J.A. Byrne and S. Simonsson).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCardiac stem cells and myocardial regeneration - Discussion \u003ci\u003e(Bernardo Nadal-Ginard, Perio Anversa, Jan Kajstura and Annarosa Leri).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eGenenration of insulin-producing cells from stem cells - Discussion \u003ci\u003e(Bernat Soria, Enrique Roche, Juan A. Reig and Franz Martin).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCell therapy for Parkinson's disease: problems and prospects - Discussion \u003ci\u003e(Anders Bjorklund).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eEthical (and political) issues in research with human stem cells - Discussion \u003ci\u003e(Thomas H. Murray).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe regulatory environment - final discussion.\u003c\/p\u003e \u003cp\u003eIndex of contributors.\u003c\/p\u003e \u003cp\u003eSubject index.\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52257034699032,"sku":"9780470091432","price":126.95,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470091432.jpg?v=1781275925","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/stem-cells-nuclear-reprogramming-and-therapeutic-applications-hardback-9780470091432","provider":"Freshly Printed Books","version":"1.0","type":"link"}