{"product_id":"signaling-pathways-in-liver-diseases-hardback-9781118663394","title":"Signaling Pathways in Liver Diseases (Hardback) 9781118663394","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eSignaling Pathways in Liver Diseases\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eJean-Francois Dufour (Edited by), J Dufour (Author), Pierre-Alain Clavien (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781118663394, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 30 October 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e520 pages\u003cbr\u003e25.2 x 19.6 x 2.8 cm, 1.279 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003eSignaling Pathways in Liver Diseases, Third Edition\u003c\/i\u003e again provides hepatologists and hepatology researchers with an expert overview of the complex and novel cellular\/extracellular signaling pathways in the liver, and their role in liver diseases. The last few years have seen a great number of developments in this field, which in turn have led to new opportunities for innovative treatments; however, the intricacy of these pathways and their interactions continue to provide a real challenge for clinicians. This outstanding book compiles the emerging knowledge into a single expert resource, cataloguing and organizing it into an accessible and understandable format.\u003c\/p\u003e \u003cp\u003eWith increased focus on the comprehension of cellular mechanisms involved in steatohepatitis, cirrhosis, and liver tumors, which has led to changes in the management of these diseases, this new edition also sees the introduction of exciting new chapters on key emerging areas such as:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eAutophagy\u003c\/li\u003e \u003cli\u003eNotch Pathway\u003c\/li\u003e \u003cli\u003eP13K\/PTEN Signaling in Liver Diseases\u003c\/li\u003e \u003cli\u003eSirtuins\u003c\/li\u003e \u003cli\u003eHepcidin and Iron\u003c\/li\u003e \u003cli\u003eEpigenetic Regulation of Hepatic Stellate Cells and Liver Fibrosis\u003c\/li\u003e \u003cli\u003eOxidative Stress and Signaling in the Liver.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003eProfessors Dufour and Clavien have assembled an all-star cast of chapter authors, each of whom has provided clear and appropriate illustrations to reinforce the text, with a key points box offering a concise and handy summary. Self-assessment questions and answers allow the reader to test their own knowledge.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eSignaling Pathways in Liver Disease, Third Edition\u003c\/i\u003e is the perfect educational and reference tool to bridge the information exchange between the laboratory, the clinical ward, and the operating room, and an essential tool for the modern-day hepatologist.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eList of Contributors, vii\u003c\/p\u003e \u003cp\u003e1 Hepatocytes 1\u003cbr\u003e\u003ci\u003eJean-François Dufour and Joachim C. Mertens\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Signaling pathways in biliary epithelial cells 15\u003cbr\u003e\u003ci\u003eM. Fatima Leite, Mateus T. Guerra, Viviane A. Andrade and Michael H. Nathanson\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Stellate cells 34\u003cbr\u003e\u003ci\u003eAlessandra Caligiuri and Fabio Marra\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Kupffer cells 61\u003cbr\u003e\u003ci\u003eAmirali Kiyani and Ekihiro Seki\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Hepatic sinusoidal endothelial cells 73\u003cbr\u003e\u003ci\u003eMoira B. Hilscher Robert C. Huebert and Vijay H. Shah\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Extracellular matrix 85\u003cbr\u003e\u003ci\u003eScott L. Friedman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Platelets: a new cell type in liver physiology 97\u003cbr\u003e\u003ci\u003eMickaël Lesurtel and Pierre]Alain Clavien\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Immune cell communication in liver disease and liver regeneration 110\u003cbr\u003e\u003ci\u003eR. Harminder Boghal, B.F. Stephenson and Simon C. Afford\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Extracellular vesicle RNA in liver disease 130\u003cbr\u003e\u003ci\u003eTushar Patel and Hiroaki Haga\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Endoplasmic reticulum stress in nonalcoholic fatty liver disease 139\u003cbr\u003e\u003ci\u003eFabienne Foufelle and Pascal Ferré\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Autophagy 151\u003cbr\u003e\u003ci\u003eHao Zhang, Bilon Khambu and Xiao]Ming Yin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 CXC chemokine receptor signaling in liver repair and regeneration 166\u003cbr\u003e\u003ci\u003eGregory C. Wilson, Christopher M. Freeman, Hiroyuki Nojima and Alex B. Lentsch\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Metabolic regulation of liver regeneration 174\u003cbr\u003e\u003ci\u003eJiansheng Huang and David A. Rudnick\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 TNF signaling 186\u003cbr\u003e\u003ci\u003eAmrit Mann, Mark J. Czaja and Jörn M. Schattenberg\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e15 Fas\/FasL 203\u003cbr\u003e\u003ci\u003eMaria Eugenia Guicciardi and Gregory J. Gores\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e16 Interferon signaling 214\u003cbr\u003e\u003ci\u003eMarkus H. Heim\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e17 Endocannabinoid signaling in liver pathologies 226\u003cbr\u003e\u003ci\u003eBostjan Humar and Nasser Semmo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e18 The WNT\/β]catenin pathway 240\u003cbr\u003e\u003ci\u003eSatdarshan P. Singh Monga\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e19 Hedgehog signaling in the liver 262\u003cbr\u003e\u003ci\u003eMariana V. Machado and Anna Mae Diehl\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e20 Notch pathway 275\u003cbr\u003e\u003ci\u003eSonja Rothweiler and David Semela\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e21 PI3K\/PTEN signaling in liver diseases 287\u003cbr\u003e\u003ci\u003eAlfredo Fort, Nicolas Calo, Dorothea Portius, Lucie Bourgoin, Marion Peyrou and Michelangelo Foti\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e22 mTOR signaling in liver disease 314\u003cbr\u003e\u003ci\u003eMarion Cornu, Grégoire de Caudron de Coquereaumont and Michael N. Hall\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e23 LKB1\/AMPK pathway in the control of hepatic energy metabolism 326\u003cbr\u003e\u003ci\u003eBenoit Viollet and Marc Fortes\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e24 NF-κB 339\u003cbr\u003e\u003ci\u003eEkihiro Seki and David A. Brenner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e25 c-Jun NH2]terminal kinases in liver diseases 348\u003cbr\u003e\u003ci\u003eJohannes Kluwe and Robert F. Schwabe\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e26 p53 364\u003cbr\u003e\u003ci\u003eAundrietta D. Duncan, Wen]Wei Tsai and Michelle Craig Barton\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e27 Sirtuins 374\u003cbr\u003e\u003ci\u003eFrank K. Huynh, Eoin McDonnell, Kristin A. Anderson and Matthew D. Hirschey\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e28 Bile acids and their receptors 385\u003cbr\u003e\u003ci\u003eThierry Claudel and Michael Trauner\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e29 Hepcidin and iron 400\u003cbr\u003e\u003ci\u003eChiara Vecchi and Antonello Pietrangelo\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e30 Gut microbiome and liver diseases 411\u003cbr\u003e\u003ci\u003eHerbert Tilg and Alexander R. Moschen\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e31 Epigenetic regulation of hepatic stellate cells and liver fibrosis 421\u003cbr\u003e\u003ci\u003eJelena Mann and Derek A. Mann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e32 Signaling in hepatocellular carcinoma 435\u003cbr\u003e\u003ci\u003eAdam Pennycuick and Augusto Villanueva\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e33 Interplay between hepatitis B virus and innate immune signaling pathways 448\u003cbr\u003e\u003ci\u003eBarbara Testoni, David Durantel and Fabien Zoulim\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e34 Signaling of hepatitis C virus 459\u003cbr\u003e\u003ci\u003eJoachim Lupberger, Nicolaas Van Renne and Thomas F. Baumert\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e35 Oxidative stress and signaling in the liver 469\u003cbr\u003e\u003ci\u003eMitchell R. McGill, Yuchao Xie and Hartmut Jaeschke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 000\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Medicine: general issues [\u003ca title=\"See our other books on Medicine: general issues\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Medicine:%20general%20issues%20%5BMB%5D%22\"\u003eMB\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Blackwell","offers":[{"title":"Brand New","offer_id":52421359730968,"sku":"9781118663394","price":138.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781118663394.jpg?v=1784592096","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/signaling-pathways-in-liver-diseases-hardback-9781118663394","provider":"Freshly Printed Books","version":"1.0","type":"link"}