{"product_id":"sensors-and-probes-for-bioimaging-hardback-9783527349609","title":"Sensors and Probes for Bioimaging (Hardback) 9783527349609","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eSensors and Probes for Bioimaging\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eYoung-Tae Chang (Author), Nam-Young Kang (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9783527349609, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 2 August 2023\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e368 pages\u003cbr\u003e24.4 x 17 x 2.4 cm, 0.879 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cb\u003eSensors and Probes for Bioimaging\u003c\/b\u003e \u003cp\u003e\u003cb\u003eA fulsome exploration of the history, design, and application of  bioimaging probes and sensors\u003c\/b\u003e \u003c\/p\u003e\n\u003cp\u003eIn \u003ci\u003eSensors and Probes for Bioimaging\u003c\/i\u003e, distinguished researcher Professor Young-Tae Chang and Professor Nam-Young Kang deliver a comprehensive discussion of  bioimaging achieved with sensors and probes. In the book, readers will find a complete discussion of the history of colorful sensors and probes, probe design and the mechanisms of staining, as well as cell and tissue application and whole-body imaging. \u003c\/p\u003e\n\u003cp\u003eYou’ll learn how probes can be used, how to choose and use a variety of probes, and new directions in research and application in the area of sensors and probes for bioimaging. \u003c\/p\u003e\n\u003cp\u003eReaders will also find: \u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eA thorough introduction to bioimaging, as well as discussions of chemical sensors and probes used in bioimaging\u003c\/li\u003e \u003cli\u003eComprehensive explorations of organelle and cell selective probes, as well as discussions of a model for organelle selectivity\u003c\/li\u003e \u003cli\u003ePractical discussions of tissue selective probes and whole-body imaging\u003c\/li\u003e \u003cli\u003eFulsome treatments of imaging for biological function and for the diagnosis of disease, including cancer and Alzheimer’s imaging\u003c\/li\u003e\n\u003c\/ul\u003e \u003cp\u003ePerfect for chemical biologists, analytical chemists, biochemists, and materials scientists, \u003ci\u003eSensors and Probes for Bioimaging\u003c\/i\u003e will also earn a place in the libraries of clinical chemists and advanced undergraduate students, graduate students, and  professionals working in the bioimaging and sensor industry.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003e1 Introduction to Bioimaging 1\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e1.1 Color 1\u003c\/p\u003e \u003cp\u003e1.2 Colorful Material 4\u003c\/p\u003e \u003cp\u003e1.3 Light Source of Bioimaging 6\u003c\/p\u003e \u003cp\u003e1.4 Subcellular Imaging 12\u003c\/p\u003e \u003cp\u003e1.5 Cell-Selective Imaging 14\u003c\/p\u003e \u003cp\u003e1.6 Tissue and Organ Imaging 14\u003c\/p\u003e \u003cp\u003e1.7 Whole-Body Imaging 15\u003c\/p\u003e \u003cp\u003e1.8 Probes in Bioimaging 15\u003c\/p\u003e \u003cp\u003eReferences 16\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Chemical Sensors and Probes for Bioimaging 17\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e2.1 History of Dyes in Biological Stains 17\u003c\/p\u003e \u003cp\u003e2.2 Blood Cell Staining 22\u003c\/p\u003e \u003cp\u003e2.3 Bacteria Staining Using Gram Method 24\u003c\/p\u003e \u003cp\u003e2.4 Fluorescent Sensors and Probes 25\u003c\/p\u003e \u003cp\u003e2.5 Representative Fluorescent Compounds for Bioimaging 29\u003c\/p\u003e \u003cp\u003eReferences 33\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Organelle-Selective Probes 35\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e3.1 Introduction 35\u003c\/p\u003e \u003cp\u003e3.2 Cell Plasma Membrane 40\u003c\/p\u003e \u003cp\u003e3.3 Endosome and Lysosome 47\u003c\/p\u003e \u003cp\u003e3.4 Nucleus and DNA 50\u003c\/p\u003e \u003cp\u003e3.5 Nucleolus and RNA 56\u003c\/p\u003e \u003cp\u003e3.6 ER and Golgi Body 58\u003c\/p\u003e \u003cp\u003e3.7 Mitochondria 62\u003c\/p\u003e \u003cp\u003e3.8 Lipid Droplet 66\u003c\/p\u003e \u003cp\u003e3.9 Peroxisome 67\u003c\/p\u003e \u003cp\u003e3.10 Cytosol 68\u003c\/p\u003e \u003cp\u003e3.11 Extracellular Vesicle 69\u003c\/p\u003e \u003cp\u003e3.12 Non-membrane-Bound Condensate 72\u003c\/p\u003e \u003cp\u003e3.13 Organelle Probes in Live Cells and Fixed Cells 74\u003c\/p\u003e \u003cp\u003e3.14 Modeling for the Organelle-Selective Probes 75\u003c\/p\u003e \u003cp\u003eReferences 80\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Live-Cell-Selective Probes 85\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e4.1 Protein-Oriented Live-Cell Distinction (POLD) 88\u003c\/p\u003e \u003cp\u003e4.1.1 Embryonic Stem Cell Probe: CDy 1 93\u003c\/p\u003e \u003cp\u003e4.1.2 Neural Stem Cell Probes 99\u003c\/p\u003e \u003cp\u003e4.1.2.1 CDr 3 99\u003c\/p\u003e \u003cp\u003e4.1.2.2 CDy5 for Neural Stem Cell Division Monitoring 103\u003c\/p\u003e \u003cp\u003e4.1.3 Tumor-Initiating Cell Probes 105\u003c\/p\u003e \u003cp\u003e4.1.3.1 TiY 105\u003c\/p\u003e \u003cp\u003e4.1.3.2 TiNIR 108\u003c\/p\u003e \u003cp\u003e4.1.4 Muscle Cell Probes 110\u003c\/p\u003e \u003cp\u003e4.1.5 Pancreatic Cell Probes 113\u003c\/p\u003e \u003cp\u003e4.1.5.1 Pancreatic α-Cell Probes 114\u003c\/p\u003e \u003cp\u003e4.1.5.2 Pancreatic β-Cell Probes 114\u003c\/p\u003e \u003cp\u003e4.1.6 Amyloid Probe: CDy 11 116\u003c\/p\u003e \u003cp\u003e4.2 Carbohydrate-Oriented Live-Cell Distinction (COLD) 118\u003c\/p\u003e \u003cp\u003e4.2.1 Lectins 121\u003c\/p\u003e \u003cp\u003e4.2.2 Embryonic Stem Cell Probes: CDg4 and CDb 8 122\u003c\/p\u003e \u003cp\u003e4.2.3 Gram-Positive Bacteria Probe 122\u003c\/p\u003e \u003cp\u003e4.2.4 Biofilm Probe: CDy14 and CDr 15 124\u003c\/p\u003e \u003cp\u003e4.3 Lipid-Oriented Live-Cell Distinction (LOLD) 128\u003c\/p\u003e \u003cp\u003e4.3.1 Filipin as a Cholesterol Probe 129\u003c\/p\u003e \u003cp\u003e4.3.2 Lipid Droplet Probes 129\u003c\/p\u003e \u003cp\u003e4.3.3 Neuron Probes 130\u003c\/p\u003e \u003cp\u003e4.3.3.1 Nissl Stains as Neuron Body Probe 131\u003c\/p\u003e \u003cp\u003e4.3.3.2 Plasma Membrane Dyes as Neuronal Network Probe 131\u003c\/p\u003e \u003cp\u003e4.3.3.3 NeuO as a Universal Neuron Probe 132\u003c\/p\u003e \u003cp\u003e4.3.4 B Lymphocyte Probe: CDgB 134\u003c\/p\u003e \u003cp\u003e4.3.5 Activated CD8 + Lymphocyte Probe: Probe 41 138\u003c\/p\u003e \u003cp\u003e4.3.6 Apoptotic Cell Probe: Apo- 15 139\u003c\/p\u003e \u003cp\u003e4.4 Gating-Oriented Live-Cell Distinction (GOLD) 139\u003c\/p\u003e \u003cp\u003e4.4.1 Cell Imaging Probes through Phagocytosis 140\u003c\/p\u003e \u003cp\u003e4.4.2 Probes Through SLC Transporters 143\u003c\/p\u003e \u003cp\u003e4.4.3 Probes Through Glucose Transporters 144\u003c\/p\u003e \u003cp\u003e4.4.4 Naïve Embryonic Stem Cell Probe: CDy 9 146\u003c\/p\u003e \u003cp\u003e4.4.5 Neurotransmitter Mimetic Probes 147\u003c\/p\u003e \u003cp\u003e4.4.6 Astrocyte Probe: SR 101 149\u003c\/p\u003e \u003cp\u003e4.4.7 Subtype-Specific Macrophage Probes: CDg16, CDr17, CDg 18 150\u003c\/p\u003e \u003cp\u003e4.4.7.1 CDg16 for Activated Macrophage 150\u003c\/p\u003e \u003cp\u003e4.4.7.2 CDr17 for M1 Macrophage 152\u003c\/p\u003e \u003cp\u003e4.4.7.3 CDg18 for M2 Macrophage 153\u003c\/p\u003e \u003cp\u003e4.4.8 B-Cell-Selective Probe Through GOLD Mechanism 153\u003c\/p\u003e \u003cp\u003e4.4.9 Bacteria Probes Through Transporters 154\u003c\/p\u003e \u003cp\u003e4.4.10 Probes Through ABC Transporters 155\u003c\/p\u003e \u003cp\u003e4.4.11 Background-Free Tame Dye 157\u003c\/p\u003e \u003cp\u003e4.5 Metabolism-Oriented Live-Cell Distinction (MOLD) 160\u003c\/p\u003e \u003cp\u003e4.5.1 Substrate for Proteases in Extracellular Matrix 160\u003c\/p\u003e \u003cp\u003e4.5.1.1 MMP12 Substrate for Activated Macrophage Probe 162\u003c\/p\u003e \u003cp\u003e4.5.1.2 Cathepsin S Substrate for Tumor-Associated Macrophage Probe 162\u003c\/p\u003e \u003cp\u003e4.5.1.3 Elastase Substrate for Neutrophil Probe 163\u003c\/p\u003e \u003cp\u003e4.5.1.4 Granzyme Substrate for Natural Killer and Cytotoxic T Cell Probe 163\u003c\/p\u003e \u003cp\u003e4.5.2 Microglia Probe: CDr10 and CDr20 165\u003c\/p\u003e \u003cp\u003e4.5.2.1 CDr10a and b for Microglia Imaging among Brain Cells 165\u003c\/p\u003e \u003cp\u003e4.5.2.2 Microglia Probe CDr20 through Ugt1a7c 169\u003c\/p\u003e \u003cp\u003e4.5.3 Neutrophil Probe: NeutropG 170\u003c\/p\u003e \u003cp\u003eReferences 172\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Ex Vivo Tissue Imaging Probes 179\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e5.1 Immunohistochemistry 181\u003c\/p\u003e \u003cp\u003e5.2 Tissue Imaging with Nucleic Acid Probes 186\u003c\/p\u003e \u003cp\u003e5.3 Tissue Imaging with Small-Molecule Probes 186\u003c\/p\u003e \u003cp\u003e5.3.1 Pancreatic Islet Imaging 188\u003c\/p\u003e \u003cp\u003e5.3.2 Neuronal Tissue Imaging 191\u003c\/p\u003e \u003cp\u003e5.4 Organoid as Model of Tissue and Organ 194\u003c\/p\u003e \u003cp\u003e5.4.1 Blood Vessel 3D Model 195\u003c\/p\u003e \u003cp\u003e5.4.2 Tumor Organoid for Drug Screening 196\u003c\/p\u003e \u003cp\u003eReferences 196\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 In Vivo Whole-Body Imaging Probes 199\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e6.1 ElaNIR for Elastin Imaging in Mouse 200\u003c\/p\u003e \u003cp\u003e6.2 Probes for Exposed Neuron in Zebrafish Embryo 201\u003c\/p\u003e \u003cp\u003e6.3 NeuO for Whole-Body Neuron Imaging in Zebrafish 202\u003c\/p\u003e \u003cp\u003e6.4 LipidGreen for Fatty Tissue Imaging in Zebrafish 203\u003c\/p\u003e \u003cp\u003e6.5 Blood Vessel Imaging in Zebrafish 204\u003c\/p\u003e \u003cp\u003e6.6 Probes for Bone Imaging 205\u003c\/p\u003e \u003cp\u003e6.7 Probes for Pancreatic Islet Imaging 206\u003c\/p\u003e \u003cp\u003e6.8 Probes for Eye Imaging 208\u003c\/p\u003e \u003cp\u003e6.8.1 Optical Coherence Tomography for Retina 209\u003c\/p\u003e \u003cp\u003e6.8.2 Fundus Photography for Blood Vessel Imaging in Retina 210\u003c\/p\u003e \u003cp\u003e6.8.3 Neuron Imaging on Retina 210\u003c\/p\u003e \u003cp\u003e6.8.4 Bacterial Infection on Cornea 211\u003c\/p\u003e \u003cp\u003e6.9 Macrophage Imaging in Ischemia and Inflammation 213\u003c\/p\u003e \u003cp\u003eReferences 214\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Imaging for Biological Environment and Function 217\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e7.1 pH 218\u003c\/p\u003e \u003cp\u003e7.2 Metal Ions 221\u003c\/p\u003e \u003cp\u003e7.2.1 Na + and K + 222\u003c\/p\u003e \u003cp\u003e7.2.2 Ca 2+ 225\u003c\/p\u003e \u003cp\u003e7.2.3 Mg 2+ 227\u003c\/p\u003e \u003cp\u003e7.2.4 Metal Ion Selectivity of Fluorescent Sensors 228\u003c\/p\u003e \u003cp\u003e7.2.5 Iron Ion 230\u003c\/p\u003e \u003cp\u003e7.2.6 Zn 2+ 230\u003c\/p\u003e \u003cp\u003e7.2.7 Copper Ion 231\u003c\/p\u003e \u003cp\u003e7.3 Metabolites 232\u003c\/p\u003e \u003cp\u003e7.3.1 Atp 232\u003c\/p\u003e \u003cp\u003e7.3.2 Nadh 233\u003c\/p\u003e \u003cp\u003e7.3.3 Histamine 234\u003c\/p\u003e \u003cp\u003e7.4 Viscosity 234\u003c\/p\u003e \u003cp\u003e7.5 Temperature 238\u003c\/p\u003e \u003cp\u003e7.5.1 ER Thermometer 238\u003c\/p\u003e \u003cp\u003e7.5.2 Mitochondrial Thermometer 240\u003c\/p\u003e \u003cp\u003e7.5.3 Organelle-Specific Fluorescent Thermometers 241\u003c\/p\u003e \u003cp\u003e7.6 Reactive Oxygen Species and Reactive Nitrogen Species 241\u003c\/p\u003e \u003cp\u003e7.6.1 Superoxide 243\u003c\/p\u003e \u003cp\u003e7.6.2 H 2 O 2 245\u003c\/p\u003e \u003cp\u003e7.6.3 Onoo − 247\u003c\/p\u003e \u003cp\u003e7.6.4 HOCl and Hypochlorite 249\u003c\/p\u003e \u003cp\u003e7.6.5 Hydroxyl Radical 251\u003c\/p\u003e \u003cp\u003eReferences 252\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Imaging for Disease 259\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e8.1 Introduction 259\u003c\/p\u003e \u003cp\u003e8.2 Cancer Imaging 260\u003c\/p\u003e \u003cp\u003e8.2.1 Imaging by Cancer-Specific Biomarker Binding 261\u003c\/p\u003e \u003cp\u003e8.2.2 Imaging by Cancer-Specific Metabolism 263\u003c\/p\u003e \u003cp\u003e8.2.3 Imaging by Cancer-Specific Transporter 267\u003c\/p\u003e \u003cp\u003e8.2.4 Imaging by the Changed Environment of Cancer 268\u003c\/p\u003e \u003cp\u003e8.2.5 Circulating Tumor Cell (CTC) 269\u003c\/p\u003e \u003cp\u003e8.2.6 Cancer Cell Line for Imaging 269\u003c\/p\u003e \u003cp\u003e8.2.7 Animal Models of Tumor Imaging 271\u003c\/p\u003e \u003cp\u003e8.2.8 Ex Vivo 3D Tumor Culture Model 275\u003c\/p\u003e \u003cp\u003e8.2.9 Clinical Imaging of Tumor for Diagnosis and Prognosis 277\u003c\/p\u003e \u003cp\u003e8.2.10 Intraoperative Imaging of Tumor 278\u003c\/p\u003e \u003cp\u003e8.3 Neurodegenerative Disease Imaging 278\u003c\/p\u003e \u003cp\u003e8.3.1 AD Imaging Through Aβ Amyloid Aggregates 278\u003c\/p\u003e \u003cp\u003e8.3.2 AD Imaging Through Tau 281\u003c\/p\u003e \u003cp\u003e8.3.3 Animal Model for AD 283\u003c\/p\u003e \u003cp\u003e8.4 Inflammation Imaging 284\u003c\/p\u003e \u003cp\u003e8.4.1 Inflammation Imaging by Environmental Changes 284\u003c\/p\u003e \u003cp\u003e8.4.2 Inflammation Imaging Through Immune Cells 285\u003c\/p\u003e \u003cp\u003e8.4.3 Inflammation Animal Model 286\u003c\/p\u003e \u003cp\u003e8.5 Diabetes Imaging 286\u003c\/p\u003e \u003cp\u003e8.6 Liver Disease Imaging 288\u003c\/p\u003e \u003cp\u003e8.7 Aging 289\u003c\/p\u003e \u003cp\u003e8.8 Theranostics 289\u003c\/p\u003e \u003cp\u003eReferences 290\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Non-optical Imaging Probes 297\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e9.1 Ultrasound Imaging Probes 297\u003c\/p\u003e \u003cp\u003e9.2 X-Ray Contrast Agents 298\u003c\/p\u003e \u003cp\u003e9.3 MRI Contrast Agents 301\u003c\/p\u003e \u003cp\u003e9.4 SPECT Probes 303\u003c\/p\u003e \u003cp\u003e9.5 PET Probes 306\u003c\/p\u003e \u003cp\u003e9.5.1 PET Probes for Tumor 307\u003c\/p\u003e \u003cp\u003e9.5.2 PET Probes for Brain Function 309\u003c\/p\u003e \u003cp\u003e9.6 Multimodality 310\u003c\/p\u003e \u003cp\u003eReferences 311\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Fluorescence Imaging Techniques and Analysis Methods 313\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e10.1 Multicolor Imaging 313\u003c\/p\u003e \u003cp\u003e10.2 Ratiometric Measurement 315\u003c\/p\u003e \u003cp\u003e10.3 Fluorescence Lifetime Imaging Microscopy 316\u003c\/p\u003e \u003cp\u003e10.4 Confocal Fluorescence Microscopy 316\u003c\/p\u003e \u003cp\u003e10.5 Two-Photon Excitation Fluorescence Imaging and Harmonic Generation 317\u003c\/p\u003e \u003cp\u003e10.6 Selective Plane Illumination Microscopy 318\u003c\/p\u003e \u003cp\u003e10.7 Total Internal Reflection Fluorescence Microscopy 319\u003c\/p\u003e \u003cp\u003e10.8 Super-Resolution Imaging 320\u003c\/p\u003e \u003cp\u003e10.9 Single-Molecule Imaging 322\u003c\/p\u003e \u003cp\u003e10.10 Photoactivation of Caged Molecule 323\u003c\/p\u003e \u003cp\u003e10.11 Fluorescence Recovery After Photobleaching 324\u003c\/p\u003e \u003cp\u003e10.12 Flow Cytometry Technique 325\u003c\/p\u003e \u003cp\u003eReferences 327\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Perspectives for Future Probe Development 329\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e11.1 Design of Selective Probes 329\u003c\/p\u003e \u003cp\u003e11.2 Discovery of Selective Probes by Screening 331\u003c\/p\u003e \u003cp\u003e11.3 Future Probe Development 336\u003c\/p\u003e \u003cp\u003eReferences 337\u003c\/p\u003e \u003cp\u003eAppendix 339\u003c\/p\u003e \u003cp\u003eIndex 341\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Other branches of medicine [\u003ca title=\"See our other books on Other branches of medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Other%20branches%20of%20medicine%20%5BMM%5D%22\"\u003eMM\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-VCH","offers":[{"title":"Brand New","offer_id":52449447051544,"sku":"9783527349609","price":110.19,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9783527349609.jpg?v=1785199633","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/sensors-and-probes-for-bioimaging-hardback-9783527349609","provider":"Freshly Printed Books","version":"1.0","type":"link"}