{"product_id":"rna-interference-application-to-drug-discovery-and-challenges-to-pharmaceutical-development-hardback-9780471771517","title":"RNA Interference; Application to Drug Discovery and Challenges to Pharmaceutical Development (Hardback) 9780471771517","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eRNA Interference\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eApplication to Drug Discovery and Challenges to Pharmaceutical Development\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003ePaul H. Johnson (Edited by), PH Johnson (Author), John J. Rossi (Foreword by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471771517, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 28 January 2011\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e336 pages\u003cbr\u003e23.9 x 16 x 2.3 cm, 0.59 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"This is an accessible book that approaches the goal of therapeutic RNAi delivery from a technological viewpoint. Chapter organization and figure presentation allow for interrupted reading without disrupting the flow. Cell and molecular biologists will find both interesting details and practical methods to improve the preclinical applicability of a research project. While therapeutic RNAi is still largely in the development stage, this book promotes a mindset to continue the search for effective delivery strategies.\" (Doody's, 7 October 2011)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003ci\u003eRNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development\u003c\/i\u003e provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eCONTRIBUTORS.  \u003cp\u003ePREFACE.\u003c\/p\u003e \u003cp\u003eFOREWORD.\u003c\/p\u003e \u003cp\u003eI. Biology of RNA Interference.\u003c\/p\u003e \u003cp\u003e1 RNA Interference: What is it? \u003ci\u003e(James A. Birchler).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Nucleic Acids as Regulatory Molecules \u003ci\u003e(Faqing Huang, C. J. Yu, and Yanlin Guo).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Use of siRNA Oligonucleotides to Study Gene Function \u003ci\u003e(Kristin A. Wiederholt and Adam N. Harris).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Genome Scanning by RNA Interference \u003ci\u003e(Roderick L. Beijersbergen and Oliver C. Steinbach).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eII Development of siRNA for Therapeutic Applications.\u003c\/p\u003e \u003cp\u003e5 Discovery of New siRNA Delivery Agents \u003ci\u003e(Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 siRNA Delivery Vehicles \u003ci\u003e(Aliasger K. Salem and Mark A. Behlke).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Interferon, Cytokine Induction and Other Potential \u003ci\u003eIn Vivo\u003c\/i\u003e Toxicities \u003ci\u003e(Adam Judge, Marjorie Robbins, and Ian MacLachlan).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Application of RNA Interference to Viral Diseases \u003ci\u003e(Ralph A. Tripp and Stephen Mark Tompkins).\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52405526364440,"sku":"9780471771517","price":107.65,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471771517.jpg?v=1784136177","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/rna-interference-application-to-drug-discovery-and-challenges-to-pharmaceutical-development-hardback-9780471771517","provider":"Freshly Printed Books","version":"1.0","type":"link"}