{"product_id":"risk-assessment-for-chemicals-in-drinking-water-hardback-9780471723448","title":"Risk Assessment for Chemicals in Drinking Water (Hardback) 9780471723448","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eRisk Assessment for Chemicals in Drinking Water\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eRobert A. Howd (Author), Anna M. Fan (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471723448, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 18 December 2007\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e400 pages\u003cbr\u003e23.9 x 16.2 x 2.4 cm, 0.671 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003eCurrently accepted for use as landscaping, it becomes clear that recycled water will be injected into drinking water chain. That use makes the material in the book more important. (\u003ci\u003eJournal of Hazardous Materials\u003c\/i\u003e, January 31, 2008)  \u003cp\u003e\"Provides a comprehensive reference on state-of-the-art risk assessment methodologies for drinking water.\" (\u003ci\u003eInternational Food Information Service\u003c\/i\u003e, 2007)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eA comprehensive reference on state-of-the-art risk assessment methodologies for drinking water\u003cbr\u003e \u003cbr\u003e \u003ci\u003eRisk Assessment for Chemicals in Drinking Water\u003c\/i\u003e discusses the major steps and goals in risk assessments and suggests ways to improve the methodologies and accuracy, while consolidating up-to-date information on the current principles and practices in one authoritative reference. After an enlightening overview of risk assessment practices and regulatory guidelines, it: \u003cul\u003e \u003cli\u003eIncludes descriptions of the use of variability analysis, exposure analysis, physiologically based pharmacokinetics, and modeling for both cancer and non-cancer endpoints\u003c\/li\u003e \u003cli\u003eDescribes the practices of major organizations, including the U.S. EPA, Health Canada, World Health Organization, and California Office of Environmental Health Hazard Assessment\u003c\/li\u003e \u003cli\u003eIncludes complete chapters on risk assessment for essential nutrients, arsenic, chloroform, and perchlorate\u003c\/li\u003e \u003cli\u003eExplains how to address susceptible sub-populations, including the elderly and infants and children, in risk assessments\u003c\/li\u003e \u003cli\u003eCovers the potential of using genomic and proteomic screens\u003c\/li\u003e \u003cli\u003eAddresses recent advances, emerging issues, and future challenges\u003c\/li\u003e \u003c\/ul\u003e With contributions and perspectives from leading scientists, this is the definitive resource for health and environmental scientists, toxicologists, risk assessors and managers, regulators, consultants, and other professionals responsible for the safety of drinking water.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003eForeword xi\u003c\/p\u003e \u003cp\u003ePreface xiii\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 Introduction to Drinking Water Risk Assessment 1\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRobert A. Howd\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDevelopment of Drinking Water Regulations 2\u003c\/p\u003e \u003cp\u003eThe Risk Assessment Process 8\u003c\/p\u003e \u003cp\u003ePublic Perceptions and the Precautionary Principle 13\u003c\/p\u003e \u003cp\u003eReferences 14\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Summary of the Development of Federal Drinking Water Regulations and Health-Based Guidelines for Chemical Contaminants 17\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJoyce Morrissey Donohue and Wynne Maynor Miller\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eSelecting Candidates for Regulatory Consideration 19\u003c\/p\u003e \u003cp\u003eKey Components for Regulatory Development 20\u003c\/p\u003e \u003cp\u003eDevelopment of Regulatory Values 28\u003c\/p\u003e \u003cp\u003eNonregulatory Options 30\u003c\/p\u003e \u003cp\u003eReferences 32\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Interpretation of Toxicologic Data for Drinking Water Risk Assessment 35\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRobert A. Howd and Anna M. Fan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAnimal Toxicity Studies 38\u003c\/p\u003e \u003cp\u003eHuman Toxicity Studies 47\u003c\/p\u003e \u003cp\u003eConclusions 57\u003c\/p\u003e \u003cp\u003eReferences 57\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Exposure Source and Multiroute Exposure Considerations for Risk Assessment of Drinking Water Contaminants 67\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eKannan Krishnan and Richard Carrier\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eExposure Source Considerations in Risk Assessment 68\u003c\/p\u003e \u003cp\u003eRoutes of Exposure and Dose Calculations 72\u003c\/p\u003e \u003cp\u003eReferences 86\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Toxicokinetics for Drinking Water Risk Assessment 91\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJohn C. Lipscomb\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eEvaluation of Toxicity Data 93\u003c\/p\u003e \u003cp\u003eToxicokinetics: PBPK Modeling 95\u003c\/p\u003e \u003cp\u003eRisk Assessment 101\u003c\/p\u003e \u003cp\u003eConclusions 117\u003c\/p\u003e \u003cp\u003eReferences 118\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Health Risk Assessment of Chemical Mixtures in Drinking Water 123\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRichard C. Hertzberg, Glenn E. Rice, Linda K. Teuschler, J. Michael Wright and Jane E. Simmons\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eDrinking Water Mixture Concerns 124\u003c\/p\u003e \u003cp\u003eEstimating Exposures to Multiple Chemicals in Drinking Water 130\u003c\/p\u003e \u003cp\u003eToxicological Concepts for Joint Toxicity 139\u003c\/p\u003e \u003cp\u003eChemical Mixtures Risk Assessment Methods 143\u003c\/p\u003e \u003cp\u003eNew Approaches for Assessing Risk from Exposure to Drinking Water Mixtures 155\u003c\/p\u003e \u003cp\u003eConclusions 162\u003c\/p\u003e \u003cp\u003eReferences 163\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Protection of Infants Children and Other Sensitive Subpopulations 171\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eGeorge V. Alexeeff and Melanie A. Marty\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eFactors Influencing Differences in Susceptibility Between Infants and Children and Adults 173\u003c\/p\u003e \u003cp\u003eCritical Systems and Periods in Development 185\u003c\/p\u003e \u003cp\u003eAge at Exposure and Susceptibility to Carcinogens 189\u003c\/p\u003e \u003cp\u003eDrinking Water Standards Developed to Protect Sensitive Subpopulations 190\u003c\/p\u003e \u003cp\u003eReferences 192\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Risk Assessment for Essential Nutrients 201\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJoyce Morrissey Donohue\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAssessment Approaches 203\u003c\/p\u003e \u003cp\u003eComparison of Guideline Values 206\u003c\/p\u003e \u003cp\u003eRisk Assessment Recommendations 210\u003c\/p\u003e \u003cp\u003eReferences 211\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Risk Assessment for Arsenic in Drinking Water 213\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eJoseph P. Brown\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eOccurrence and Exposure 214\u003c\/p\u003e \u003cp\u003eMetabolism 216\u003c\/p\u003e \u003cp\u003eHealth Effects 221\u003c\/p\u003e \u003cp\u003eRisk Assessment 245\u003c\/p\u003e \u003cp\u003eConclusions 250\u003c\/p\u003e \u003cp\u003eReferences 252\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Risk Assessment for Chloroform Reconsidered 267\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eRichard Sedman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eCarcinogenic Effects 268\u003c\/p\u003e \u003cp\u003eNoncancer Toxic Effects 268\u003c\/p\u003e \u003cp\u003eMechanisms of Carcinogenicity 271\u003c\/p\u003e \u003cp\u003eRegulation of Cancer Risk 280\u003c\/p\u003e \u003cp\u003eDiscussion 281\u003c\/p\u003e \u003cp\u003eReferences 283\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 Risk Assessment of a Thyroid Hormone Disruptor: Perchlorate 287\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eDavid Ting\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eBackground 287\u003c\/p\u003e \u003cp\u003eHuman Health Risk Assessment 292\u003c\/p\u003e \u003cp\u003eRisk Characterization and Conclusions 296\u003c\/p\u003e \u003cp\u003eReferences 298\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Emerging Contaminants in Drinking Water: A California Perspective 303\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eSteven A. Book and David P. Spath\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eEmerging Chemicals of the Recent Past 304\u003c\/p\u003e \u003cp\u003eNewer Emerging Contaminants 306\u003c\/p\u003e \u003cp\u003eFuture Emerging Chemicals 306\u003c\/p\u003e \u003cp\u003eConclusions 311\u003c\/p\u003e \u003cp\u003eReferences 312\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 U.S. EPA Drinking Water Field Office Perspectives and Needs for Risk Assessment 315\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eBruce A. Macler\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eThe Nature of Regulatory Risk Assessments 315\u003c\/p\u003e \u003cp\u003eUse of Drinking Water Risk Information in EPA Field Offices 318\u003c\/p\u003e \u003cp\u003eConclusions 322\u003c\/p\u003e \u003cp\u003eReferences 322\u003c\/p\u003e \u003cp\u003e\u003cb\u003e14 Risk Assessment: Emerging Issues Recent Advances and Future Challenges 325\u003cbr\u003e\u003c\/b\u003e\u003ci\u003eAnna M. Fan and Robert A. Howd\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eEmerging Issues 326\u003c\/p\u003e \u003cp\u003eAdvances in Science Approaches and Methods 332\u003c\/p\u003e \u003cp\u003eConclusions 357\u003c\/p\u003e \u003cp\u003eReferences 359\u003c\/p\u003e \u003cp\u003eIndex 365\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Interscience","offers":[{"title":"Brand New","offer_id":52298045030680,"sku":"9780471723448","price":114.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471723448.jpg?v=1781732510","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/risk-assessment-for-chemicals-in-drinking-water-hardback-9780471723448","provider":"Freshly Printed Books","version":"1.0","type":"link"}