{"product_id":"protein-aggregation-in-bacteria-functional-and-structural-properties-of-inclusion-bodies-in-bacterial-cells-hardback-9781118448526","title":"Protein Aggregation in Bacteria; Functional and Structural Properties of Inclusion Bodies in Bacterial Cells (Hardback) 9781118448526","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eProtein Aggregation in Bacteria\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eFunctional and Structural Properties of Inclusion Bodies in Bacterial Cells\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eSilvia Maria Doglia (Edited by), S Doglia (Author), Marina Lotti (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781118448526, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 8 August 2014\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e288 pages\u003cbr\u003e24.4 x 16.3 x 2 cm, 0.567 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003eFocuses on the aggregation of recombinant proteins in bacterial cells in the form of inclusion bodies—and on their use in biotechnological and medical applications\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eThe first book devoted specifically to the topic of aggregation in bacteria, \u003ci\u003eProtein Aggregation in Bacteria: Functional and Structural Properties of Inclusion Bodies in Bacterial Cells\u003c\/i\u003e provides a large overview of protein folding and aggregation, including cell biology and methodological aspects. It summarizes, for the first time in one book, ideas and technical approaches that pave the way for a direct use of inclusion bodies in biotechnological and medical applications.\u003c\/p\u003e \u003cp\u003e\u003ci\u003eProtein Aggregation in Bacteria\u003c\/i\u003e covers:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eMolecular and cellular mechanisms of protein folding, aggregation, and disaggregation in bacteria\u003c\/li\u003e \u003cli\u003ePhysiological importance and consequences of aggregation for the bacterial cell\u003c\/li\u003e \u003cli\u003eFactors inherent to the protein sequence responsible for aggregation and evolutionary mechanisms to keep proteins soluble\u003c\/li\u003e \u003cli\u003eStructural properties of proteins expressed as soluble aggregates and as inclusion bodies within bacterial cells both from a methodological point of view and with regard to their similarity with amyloids\u003c\/li\u003e \u003cli\u003eControl of the structural and functional properties of aggregated proteins and use thereof in biotechnology and medicine\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003eProtein Aggregation in Bacteria\u003c\/i\u003e is ideal for researchers in protein science, biochemistry, bioengineering, biophysics, microbiology, medicine, and biotechnology, particularly if they are related with the production of recombinant proteins and pharmaceutical science.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eContributors vii\u003c\/p\u003e \u003cp\u003ePreface xi\u003c\/p\u003e \u003cp\u003eIntroduction to the Wiley Series in Protein and Peptide Science xiii\u003c\/p\u003e \u003cp\u003e1 Fundamentals of Protein Folding 1\u003cbr\u003e \u003ci\u003eVladimir N. Uversky\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Recruiting Unfolding Chaperones to Solubilize Misfolded Recombinant Proteins 63\u003cbr\u003e \u003ci\u003eRayees U.H. Mattoo and Pierre Goloubinoff\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Osmolytes as Chemical Chaperones to Use in Protein Biotechnology 77\u003cbr\u003e \u003ci\u003eArio de Marco\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Inclusion Bodies in the Study of Amyloid Aggregation 93\u003cbr\u003e \u003ci\u003eAnna Villar-Piqué and Salvador Ventura\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Protein Aggregation in Unicellular Eukaryotes 117\u003cbr\u003e \u003ci\u003eMarina Caldara, Joris Winderickx, and Vanessa Franssens\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Structural Properties of Bacterial Inclusion Bodies 151\u003cbr\u003e \u003ci\u003eAntonino Natalello, Diletta Ami, and Silvia Maria Doglia\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Residue-Specific Structural Studies of Inclusion Bodies 181\u003cbr\u003e \u003ci\u003eChristian Wasmer, Marielle Wälti, Yongli Chen, and Lei Wang\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Biomedical Applications of Bacterial Inclusion Bodies 203\u003cbr\u003e Imma Ratera, Spela Peternel, Joaquin Seras-Franzoso, Olivia Cano-Garrido, Elena García-Fruitós, Rafael Cubarsí, Esther Vazquez, José Luis Corchero, Escarlata Rodríguez-Carmona, Jaume Veciana, and Antonio Villaverde\u003c\/p\u003e \u003cp\u003e9 Aggregation of Recombinant Proteins: Understanding Basic Issues to Overcome Production Bottlenecks 221\u003cbr\u003e \u003ci\u003eMarina Lotti and Loredano Pollegioni\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Fusion to a Pull-Down Module: Designing Enzymes to Form Biocatalytically Active Insoluble Aggregates 247\u003cbr\u003e \u003ci\u003eBernd Nidetzky\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 263\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52417775173912,"sku":"9781118448526","price":95.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781118448526.jpg?v=1784508252","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/protein-aggregation-in-bacteria-functional-and-structural-properties-of-inclusion-bodies-in-bacterial-cells-hardback-9781118448526","provider":"Freshly Printed Books","version":"1.0","type":"link"}