{"product_id":"predictive-methods-for-genomics-and-evolution-towards-a-new-analytical-biology-hardback-9781394317424","title":"Predictive Methods for Genomics and Evolution; Towards a New Analytical Biology (Hardback) 9781394317424","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003ePredictive Methods for Genomics and Evolution\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eTowards a New Analytical Biology\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eMax Garzon (Author), Luis F. Garcia (Author), Alexander Colorado (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781394317424, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 17 October 2025\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e272 pages\u003cbr\u003e24.4 x 17 x 1.6 cm, 0.771 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003cb\u003eInnovative title providing a systematic account of new alignment-free methods in genomics and bioinformatics, emphasizing their potential to add predictive capabilities to address major and current questions in the science of biology\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003ePredictive Methods for Genomics and Evolution\u003c\/i\u003e provides a cohesive overview of major alignment-based and alignment-free methods in genomics and bioinformatics, primarily based on DNA\/RNA. Throughout the book, contrasts between current conventional methods and novel alignment-free methods are presented and evaluated across a wide range of topics.\u003c\/p\u003e \u003cp\u003eWritten by a team of experienced academics with significant research experience in the field, \u003ci\u003ePredictive Methods for Genomics and Evolution\u003c\/i\u003e discusses major topics including:\u003c\/p\u003e \u003cul\u003e \u003cli\u003eMajor unresolved problems in biology including the most fundamental concept of species, the nature of evolution and speciation, phylogenetic inference, pathogenicity, and the origin of life\u003c\/li\u003e \u003cli\u003eNovel interpretations of current hypotheses from a biological perspective with wide-ranging applications in bioinformatics and medicine\u003c\/li\u003e \u003cli\u003eInsights on the shift in the research status quo towards a wider application of more efficient alignment-free methodologies, fueled by the increased availability of data, deeper knowledge of DNA\/RNA structure and powerful methods from the fields of machine learning and data science.\u003c\/li\u003e \u003c\/ul\u003e \u003cp\u003e\u003ci\u003ePredictive Methods for Genomics and Evolution\u003c\/i\u003e is an essential guide on the subject for professionals, academics, researchers, and students within the fields of genomics, evolutionary biology, phylogenetics and taxonomy, and computational biology and bioinformatics, as well as medical practitioners in related fields.\u003cbr\u003e \u003cbr\u003eA companion website for this text can be found here: bmc.memphis.edu\/predBiology\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface xi\u003cbr\u003eAcknowledgments xiii\u003cbr\u003eAcronyms xv\u003c\/p\u003e \u003cp\u003e\u003cb\u003e1 What Is Biology? 1\u003c\/b\u003e\u003cbr\u003e1.1 DNA: Nature, Role, and Function 3\u003cbr\u003e1.2 Hybridization Affinity 19\u003cbr\u003e1.3 Summary 30\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Genomes to Phenotypes, Environments, and Genomes 37\u003c\/b\u003e\u003cbr\u003e2.1 Phenotype Determination: The Conventional View 37\u003cbr\u003e2.2 Environments and Autopoiesis 45\u003cbr\u003e2.3 Phenotype Determination: An Alternative View 47\u003cbr\u003e2.4 Summary 52\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Species Definitions and Their Limitations 57\u003c\/b\u003e\u003cbr\u003e3.1 The Importance of the Concept of Species 57\u003cbr\u003e3.2 Current Species Definitions 62\u003cbr\u003e3.3 What Exactly Is a \"Species\"? 69\u003cbr\u003e3.4 A Deeper Definition of \"Species\" 73\u003cbr\u003e3.5 Summary 84\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Speciation and Evolution 89\u003c\/b\u003e\u003cbr\u003e4.1 Darwinian Evolution 89\u003cbr\u003e4.2 Neo-Darwinian Evolution: The Modern Synthesis 94\u003cbr\u003e4.3 Speciation Processes 97\u003cbr\u003e4.4 Summary 108\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 From Genomes to Evolution 113\u003c\/b\u003e\u003cbr\u003e5.1 From Genotypes to Phenotypes: Evolutionary Scale 114\u003cbr\u003e5.2 Is the Course of Evolution Predictable at the Macroscale? 120\u003cbr\u003e5.3 Is the Course of Evolution Predictable at the Lineage Scale? 125\u003cbr\u003e5.4 Summary 134\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Conventional Phylogenetics and Systematics 139\u003c\/b\u003e\u003cbr\u003e6.1 DNA: The Thin Thread of Life 140\u003cbr\u003e6.2 Distance Methods versus Parsimony Analysis 146\u003cbr\u003e6.3 Probabilistic Methods and Evolutionary Models 149\u003cbr\u003e6.4 Case Study in Molecular Taxonomy: COI 155\u003cbr\u003e6.5 Summary 165\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 New Approaches to Phylogenetics 173\u003c\/b\u003e\u003cbr\u003e7.1 Phylogenetic Trees 173\u003cbr\u003e7.2 Phylogenetic Tree Assessment 177\u003cbr\u003e7.3 Phylogenetic Hypotheses Based on Deep DNA Structure 178\u003cbr\u003e7.4 Summary 180\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 About the Origin of Life 185\u003c\/b\u003e\u003cbr\u003e8.1 Theories of the Origin of Life on Earth: From Creationism to Panspermia 185\u003cbr\u003e8.2 Complex Systems: A Holistic Approach 188\u003cbr\u003e8.3 A Case Study: Polytene Chromosomes in Black Flies 195\u003cbr\u003e8.4 Summary 210\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Toward an Analytical Biology 217\u003c\/b\u003e\u003cbr\u003e9.1 What Is Data Science (DS)? 218\u003cbr\u003e9.2 What Is Machine Learning (ML)? 224\u003cbr\u003e9.3 Causality vs. Correlation 226\u003cbr\u003e9.4 What Is Artificial Intelligence (AI)? 228\u003cbr\u003e9.5 The Natural Intelligence of DNA and Biological Organisms 229\u003cbr\u003e9.6 Summary 231\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Appendices 235\u003c\/b\u003e\u003cbr\u003e10.1 Genotypes 235\u003cbr\u003e10.2 Standard Biological Taxonomies 235\u003cbr\u003e10.3 Divergence in Black Flies 238\u003cbr\u003e10.4 Software 244\u003c\/p\u003e \u003cp\u003eBibliography 244\u003cbr\u003eIndex 245\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Biology, life sciences [\u003ca title=\"See our other books on Biology, life sciences\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Biology,%20life%20sciences%20%5BPS%5D%22\"\u003ePS\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52507411775768,"sku":"9781394317424","price":111.89,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781394317424.jpg?v=1786445991","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/predictive-methods-for-genomics-and-evolution-towards-a-new-analytical-biology-hardback-9781394317424","provider":"Freshly Printed Books","version":"1.0","type":"link"}