{"product_id":"physiologically-based-pharmacokinetic-pbpk-modeling-methods-and-applications-in-toxicology-and-risk-assessment-paperback-9780128185964","title":"Physiologically Based Pharmacokinetic (PBPK) Modeling; Methods and Applications in Toxicology and Risk Assessment (Paperback) 9780128185964","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003ePhysiologically Based Pharmacokinetic (PBPK) Modeling\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eMethods and Applications in Toxicology and Risk Assessment\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003e\u003cp\u003eFoundational resource that provides practical, applied training on how to develop, calibrate and evaluate a PBPK model in toxicology and risk assessment\u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eJeffrey W. Fisher (Edited by), Jeffery M. Gearhart (Edited by), Zhoumeng Lin (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128185964, Elsevier Science\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 21 May 2020\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e346 pages\u003cbr\u003e23.4 x 19 x 2.2 cm, 0.84 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003ePhysiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment\u003c\/i\u003e presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic principles, classical physiological models, the application of physiological models for dose-response and risk assessment, the use of in vitro information, and in silico methods. With end-of-chapter exercises that allow readers to practice and learn the skills associated with PBPK modeling, dose-response, and its applications to safety and risk assessments, this book is a foundational resource that provides practical coverage of PBPK modeling for graduate students, academics, researchers, and more.\u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003eForeword Melvin Andersen\u003c\/p\u003e \u003cp\u003ePreface Jeffrey W. Fisher, Zhoumeng Lin and Jeffery M. Gearhart\u003c\/p\u003e \u003cp\u003e1. A history and recent efforts of selected physiologically based pharmacokinetic modeling topics Zhoumeng Lin and Jeffrey W. Fisher\u003c\/p\u003e \u003cp\u003e2. Introduction to classical pharmacokinetics Shruti V. Kabadi and Zhoumeng Lin\u003c\/p\u003e \u003cp\u003e3. Fundamentals of physiologically based pharmacokinetic modeling Jeff Fisher, Xiaoxia Yang, Darshan Mehta, Conrad Housand and Zhoumeng Lin\u003c\/p\u003e \u003cp\u003e4. Physiologically based pharmacokinetic modeling software C.E. Hack, A.Y. Efremenko, S.N. Pendse, C.A. Ellison, A. Najjar, N. Hewitt, A. Schepky and H.J. Clewell III\u003c\/p\u003e \u003cp\u003e5. Chemical absorption and writing code for portals of entry Jeffrey W. Fisher, Jeffery M. Gearhart, Jerry L. Campbell Jr and Darshan Mehta\u003c\/p\u003e \u003cp\u003e6. Physiologically based pharmacokinetic model: distribution processes Christopher Ruark\u003c\/p\u003e \u003cp\u003e7. Metabolism and physiologically based pharmacokinetic models Jeffrey W. Fisher, Jerry L. Campbell Jr. and Zhoumeng Lin\u003c\/p\u003e \u003cp\u003e8. Physiologically based pharmacokinetic model: excretion via urine, feces, and breath Sami Haddad and Andy Nong\u003c\/p\u003e \u003cp\u003e9. Sensitivity and Monte Carlo analysis techniques and their use in uncertainty, variability, and population analysis Tammie R. Covington and Jeffery M. Gearhart\u003c\/p\u003e \u003cp\u003e10. Physiologically based pharmacokinetic model calibration, evaluation, and performance assessment Zhoumeng Lin, Yi-Hsien Cheng, Wei-Chun Chou and Miao Li\u003c\/p\u003e \u003cp\u003e11. Examples of physiologically based pharmacokinetic modeling applied to risk assessment Lisa M. Sweeney and Jeffery M. Gearhart\u003c\/p\u003e \u003cp\u003e12. Physiologically based pharmacokinetic models to support modernized chemical safety assessment Miyoung Yoon\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Public health \u0026amp; preventive medicine [\u003ca title=\"See our other books on Public health \u0026amp; preventive medicine\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Public%20health%20\u0026amp;%20preventive%20medicine%20%5BMBN%5D%22\"\u003eMBN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Academic Press","offers":[{"title":"Default Title","offer_id":46648979194136,"sku":"9780128185964","price":119.45,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128185964.jpg?v=1694095835","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/physiologically-based-pharmacokinetic-pbpk-modeling-methods-and-applications-in-toxicology-and-risk-assessment-paperback-9780128185964","provider":"Freshly Printed Books","version":"1.0","type":"link"}