{"product_id":"pharmaceutical-amorphous-solid-dispersions-hardback-9781118455203","title":"Pharmaceutical Amorphous Solid Dispersions (Hardback) 9781118455203","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003ePharmaceutical Amorphous Solid Dispersions\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eAnn Newman (Edited by), AW Newman (Author)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9781118455203, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 24 April 2015\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e512 pages\u003cbr\u003e23.4 x 16 x 3.3 cm, 0.816 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003e\u003cb\u003ePharmaceutical Amorphous Solid Dispersions\u003c\/b\u003e\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eProviding a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today's pharmaceutical industry.\u003c\/p\u003e \u003cul\u003e \u003cli\u003eHelps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems\u003c\/li\u003e \u003cli\u003eCovers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property, and regulatory considerations\u003c\/li\u003e \u003cli\u003eHas an appendix with structure and property information for polymers commonly used in drug development and with marketed drugs developed using the amorphous sold dispersion approach\u003c\/li\u003e \u003cli\u003eAddresses global regulatory issues including USA regulations, ICH guidelines, and patent concerns around the world\u003c\/li\u003e \u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface ix\u003c\/p\u003e \u003cp\u003eContributors xi\u003c\/p\u003e \u003cp\u003e1 Introduction to Amorphous Solid Dispersions 1\u003cbr\u003e \u003ci\u003eGeorge Zografi and Ann Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Polymers and Surfactants 42\u003cbr\u003e \u003ci\u003ePadma Narayan, William W. Porter III, Meinolf Brackhagen, and Christopher Tucker\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Amorphous Solid Dispersion Screening 85\u003cbr\u003e \u003ci\u003eAnn Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Solid-state Characterization of Amorphous Dispersions 117\u003cbr\u003e \u003ci\u003eFrederick G. Vogt\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Physical Stability and Crystallization Inhibition 179\u003cbr\u003e \u003ci\u003eLynne S. Taylor\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Solubility and Dissolution Considerations for Amorphous Solid Dispersions 218\u003cbr\u003e \u003ci\u003eGrace A. Ilevbare, Wei Xu, Christopher T. John, James D. Ormes, Jesse L. Kuiper, Allen C. Templeton, and Annette Bak\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Translational Development of Amorphous Dispersions 259\u003cbr\u003e \u003ci\u003ePatrick R. Connelly, Brian Patrick Quinn, Steve Johnston, Philip Bransford, Praveen Mudunuri, Andrey Peresypkin, Majed Fawaz, Setu Roday, Anuj Kuldipkumar, Hong-Ren Wang, Phillip Snyder, Jeff Katstra, Tapan Sanghvi, Bill Rowe, and Patricia Hurter\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Preclinical and Clinical Studies 288\u003cbr\u003e \u003ci\u003eMarcus E. Brewster, Geert Verreck, Jan Bevernage, Joachim Brouwers, Guy Van den Mooter, and Patrick Augustijns Copyrighted Material\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Spray Drying and Scale-up 315\u003cbr\u003e \u003ci\u003eDaniel E. Dobry, Dana M. Settell, and John M. Baumann\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Hot Melt Extrusion of Amorphous Solid Dispersions 341\u003cbr\u003e \u003ci\u003eKieran Crowley and Andreas Gryczke\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Formulation Development of Amorphous Dispersions 364\u003cbr\u003e \u003ci\u003eTapan Sanghvi, Jeff Katstra, Brian Patrick Quinn, Hayden Thomas, and Patricia Hurter\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 Scientific and Regulatory Considerations in Product Development 398\u003cbr\u003e \u003ci\u003eAbhay Gupta, Ziyaur Rahman, and Mansoor A. Khan\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Patenting Amorphous Solid Dispersions of Pharmaceuticals 415\u003cbr\u003e \u003ci\u003eJeffrey A. Lindeman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e14 Monographs on Polymers and Surfactants 433\u003cbr\u003e \u003ci\u003eXia Lu, Robert Wenslow, and Ann Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAppendix a 455\u003cbr\u003e \u003ci\u003eXia Lu, Robert Wenslow, and Ann Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eAppendix B: Marketed Products 470\u003cbr\u003e \u003ci\u003eAnn Newman\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 473\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52417775796504,"sku":"9781118455203","price":106.99,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9781118455203.jpg?v=1784508259","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/pharmaceutical-amorphous-solid-dispersions-hardback-9781118455203","provider":"Freshly Printed Books","version":"1.0","type":"link"}