{"product_id":"pathway-analysis-for-drug-discovery-computational-infrastructure-and-applications-hardback-9780470107058","title":"Pathway Analysis for Drug Discovery; Computational Infrastructure and Applications (Hardback) 9780470107058","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003ePathway Analysis for Drug Discovery\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eComputational Infrastructure and Applications\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eAnton Yuryev (Edited by), A Yuryev (Author), Sean Ekins (Series edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780470107058, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 17 October 2008\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e336 pages\u003cbr\u003e24.1 x 16.1 x 2.2 cm, 0.617 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"Pathway analysis will help lead to a better understanding of the chemistry of living systems and the aberrations that disrupt health. This new book will serve as a beacon to research interested in this field.\" (\u003ci\u003eJournal of Medicinal Chemistry\u003c\/i\u003e, April 9, 2009)\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eThis book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003ePreface vii\u003c\/p\u003e \u003cp\u003eContributors ix\u003c\/p\u003e \u003cp\u003e1 Introduction to Pathway Analysis 1\u003cbr\u003e \u003ci\u003eAnton Yuryev\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e2 Software Infrastructure and Data Model for Pathway Analysis 27\u003cbr\u003e \u003ci\u003eFedor Bokov and Anton Yuryev\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e3 Automatic Pathway Inference in Heterogeneous Biological Association Networks 47\u003cbr\u003e \u003ci\u003eAnton Yuryev, Andrey Kalinin, and Nikolai Daraselia\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e4 Algorithmic Basis for Pathway Visualization 67\u003cbr\u003e \u003ci\u003eSergey Simakov, Iaroslav Ispolatov, Sergei Maslov, and Alexander Nikitin\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e5 Pathway Analysis of High-Throughput Experimental Data 103\u003cbr\u003e \u003ci\u003eAndrey Y. Sivachenko\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e6 Integrative Pathway Analysis of Disease Molecular Data 121\u003cbr\u003e \u003ci\u003eAndrej Bugrim, Zoltan Dezso, Yuri Nikolsky, and Tatiana Nikolskaya\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e7 Whole-Genome Expression Profiling of Papillary Serous Ovarian Cancer: Activated Pathways,Potential Targets, and Noise 149\u003cbr\u003e \u003ci\u003eJohn Farley, Laurent L. Ozbun, and Michael J. Birrer\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e8 Mammalian Proteome and Toxicant Network Analysis 165\u003cbr\u003e \u003ci\u003eSean Ekins and Craig N. Giroux\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e9 Unraveling Mechanisms of Toxicity with the Power of Pathways: ToxWiz Tool as an IllustrativeExample 195\u003cbr\u003e \u003ci\u003eMark P. Kühnel, Bojana Cosovic, Goran Medic, Robert B. Russell, and Gordana Apic\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e10 Impact of Chemistry Information on Pathway Analysis 219\u003cbr\u003e \u003ci\u003eSreenivas Devidas\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e11 Propagation of Concentration Perturbations in Equilibrium Protein Binding Networks 237\u003cbr\u003e \u003ci\u003eSergei Maslov and Iaroslav Ispolatov\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e12 An Adaptive System Model of the Yeast Glucose Sensor System 263\u003cbr\u003e \u003ci\u003eTodor Vujasinovic and André Siniša Žampera\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e13 Present and Future of Pathway Analysis in Drug Discovery 285\u003cbr\u003e \u003ci\u003eAnton Yuryev\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003eIndex 297\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley","offers":[{"title":"Brand New","offer_id":52257071300888,"sku":"9780470107058","price":83.29,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780470107058.jpg?v=1781276279","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/pathway-analysis-for-drug-discovery-computational-infrastructure-and-applications-hardback-9780470107058","provider":"Freshly Printed Books","version":"1.0","type":"link"}