{"product_id":"palladium-catalyzed-modification-of-nucleosides-nucleotides-and-oligonucleotides-paperback-9780128112922","title":"Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides (Paperback) 9780128112922","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003ePalladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003cp\u003eCovers the protocols and procedures for modifying nucleosides, nucleotides and oligonucleotides using Pd-mediated cross-coupling reactions \u003c\/p\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eAnant R. Kapdi (Edited by), Debabrata Maiti (Edited by), Yogesh S. Sanghvi (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780128112922\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback, published 6 June 2018\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e358 pages\u003cbr\u003e22.9 x 15.1 x 2.3 cm, 0.59 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e\u003ci\u003ePalladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides\u003c\/i\u003e describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. Users will find key synthetic protocols for these reactions in this latest volume in the \u003ci\u003eLatest Trends in Palladium Chemistry \u003c\/i\u003eseries. As most of the research in the field of antiviral agents has centered on the use of modified nucleosides that have exhibited promising activity, this book provides an up-to-date reference for both professionals in industry and other interested parties. \u003c\/p\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. Future of Drug Discovery: Importance of modified nucleosides, Nucleotides and Oligonucleotides 2. Stille Cross-Coupling Reaction: Early years to the current state-of the art 3. Suzuki-Miyaura Cross-Coupling as a Synthetic Tool for Nucleoside and Nucleotide Modification 4. Sonogashira Cross-Coupling: Alkyne-modified Nucleosides and their Applications 5. Application of Heck Alkenylation Reaction in Modified Nucleoside Synthesis 6. Nucleosides Modification Using Buchwald-Hartwig Amination Reactions 7. Transition-Metal Catalyzed Modification of Nucleosides 8. C-H Bond Functionalisation Strategies for Modification of Nucleosides 9. Synthesis and applications of water soluble Pd-catalyst systems for introduction of C-C bond in nucleosides 10. Advances in application of Pd-mediated transformations in nucleotides and oligonucleotides \u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Inorganic chemistry [\u003ca title=\"See our other books on Inorganic chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Inorganic%20chemistry%20%5BPNK%5D%22\"\u003ePNK\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Freshly Printed Books","offers":[{"title":"Default Title","offer_id":46649774604568,"sku":"9780128112922","price":100.29,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780128112922.jpg?v=1694103391","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/palladium-catalyzed-modification-of-nucleosides-nucleotides-and-oligonucleotides-paperback-9780128112922","provider":"Freshly Printed Books","version":"1.0","type":"link"}