{"product_id":"new-frontiers-in-asymmetric-catalysis-hardback-9780471680260","title":"New Frontiers in Asymmetric Catalysis (Hardback) 9780471680260","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eNew Frontiers in Asymmetric Catalysis\u003c\/font\u003e\u003cbr\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003c\/p\u003e\n\u003cp\u003e\u003cfont size=\"4\"\u003eKoichi Mikami (Edited by), K Mikami (Author), Mark Lautens (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780471680260, Wiley\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eHardback, published 25 May 2007\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e448 pages\u003cbr\u003e24.2 x 16.4 x 2.8 cm, 0.765 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cem\u003e\u003cfont size=\"3\"\u003e\"[The] editors have succeeded admirably in inviting interesting authors to assemble a handy overview of the most important reactions and a number of concepts ... .The present monograph has achieved the goal of covering truly interesting reactions and catalysts.\" (\u003ci\u003eOrganic Chemistry Portal\u003c\/i\u003e, May 2009)  \u003cp\u003e\"...this book has definite value and is strongly recommended for inclusion in both academic and industrial research libraries.\"  (\u003ci\u003eAngewandte Chemie, Intern. Edition\u003c\/i\u003e, November 2007)\u003c\/p\u003e\u003c\/font\u003e\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eA compilation of recent advances and applications in asymmetric catalysis\u003cbr\u003e \u003cbr\u003e The field of asymmetric catalysis has grown rapidly and plays a key role in drug discovery and pharmaceuticals. New Frontiers in Asymmetric Catalysis gives readers a fundamental understanding of the concepts and applications of asymmetric catalysis reactions and discusses the latest developments and findings. With contributions from preeminent scientists in their respective fields, it covers:\u003cbr\u003e \u003cbr\u003e * \"Rational\" ligand design, which is critically dependent on the reaction type (reduction, oxidation, and C-C bond formation) \u003cbr\u003e * Recent findings on activation of C-H bonds, C-C bonds, and small molecules (C=O, HCN, RN=C, and CO2) and the latest developments on C-C bond reorganization, such as metathesis \u003cbr\u003e * Advances in \"chirally economical\" non-linear phenomena, racemic catalysis, and autocatalysis \u003cbr\u003e * Some of the recent discoveries that have led to a renaissance in the field of organocatalysis, including the development of chiral Brönstead acids and Lewis acidic metals bearing the conjugate base of the Brönstead acids as the ligands and the chiral bi-functional acid\/base catalysts \u003cbr\u003e \u003cbr\u003e The book ends with a thought-provoking perspective on the future of asymmetric catalysis that addresses both the challenges and the unlimited potential in this burgeoning field. This is an authoritative, up-to-date reference for organic chemists in academia, government, and industries, including pharmaceuticals, biotech, fine chemicals, polymers, and agriculture. It is also an excellent textbook for graduate students studying advanced organic chemistry or chemical synthesis.\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePREFACE.  \u003cp\u003eCONTRIBUTORS.\u003c\/p\u003e \u003cp\u003e1 Ligand Design for Catalytic Asymmetric Reduction (\u003ci\u003eTakeshi Ohkuma, Masato Kitamura, and Ryoji Noyori\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e1.1 Introduction.\u003c\/p\u003e \u003cp\u003e1.2 Hydrogenation of Olefins.\u003c\/p\u003e \u003cp\u003e1.3 Reduction of Ketones.\u003cbr\u003e \u003c\/p\u003e \u003cp\u003e1.4 Reduction of Imines.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e2 Ligand Design for Oxidation\u003c\/b\u003e (\u003ci\u003eTohru Yamada\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e2.1 Introduction.\u003c\/p\u003e \u003cp\u003e2.2 Catalytic Enantioselective Epoxidation of Unfunctionalized Olefins.\u003c\/p\u003e \u003cp\u003e2.3 Enantioselective Metal-Catalyzed Baeyer–Villiger Oxidation.\u003c\/p\u003e \u003cp\u003e2.4 Optical Resolution during Oxidation of Alcohols.\u003c\/p\u003e \u003cp\u003e2.5 Catalytic Enantioselective Oxidative Coupling of 2-Naphthols.\u003c\/p\u003e \u003cp\u003e2.6 Concluding Remarks.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e3 Ligand Design for C–C Bond Formation\u003c\/b\u003e (\u003ci\u003eRyo Shintani and Tamio Hayashi\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e3.1 Introduction.\u003c\/p\u003e \u003cp\u003e3.2 1,4-Addition and Related Reactions.\u003c\/p\u003e \u003cp\u003e3.3 Cross-Coupling Reactions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e4 Activation of Small Molecules (CO, HCN, RNC, and CO\u003c\/b\u003e\u003cb\u003e\u003csub\u003e2\u003c\/sub\u003e\u003c\/b\u003e\u003cb\u003e)\u003c\/b\u003e (\u003ci\u003eKyoko Nozaki\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e4.1 Introduction.\u003c\/p\u003e \u003cp\u003e4.2 Asymmetric Hydroformylation of Olefins.\u003c\/p\u003e \u003cp\u003e4.3 Asymmetric Hydrocarbohydroxylation and Related Reactions.\u003c\/p\u003e \u003cp\u003e4.4 Asymmetric Ketone Formation from Carbon–Carbon Multiple Bonds and CO.\u003c\/p\u003e \u003cp\u003e4.5 Asymmetric Hydrocyanation of Olefins.\u003c\/p\u003e \u003cp\u003e4.6 Asymmetric Addition of Cyanide and Isocyanide to Aldehydes or Imines.\u003c\/p\u003e \u003cp\u003e4.7 Asymmetric Addition of Carbon Dioxide.\u003c\/p\u003e \u003cp\u003e4.8 Conclusion and Outlook.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e5 Asymmetric Synthesis Based on Catalytic Activation of CH Bonds and CC Bonds\u003c\/b\u003e (\u003ci\u003eZhiping Li and Chao-Jun Li\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e5.1 Introduction.\u003c\/p\u003e \u003cp\u003e5.2 Asymmetric Synthesis via Activation of C–H Bonds.\u003c\/p\u003e \u003cp\u003e5.3 Asymmetric Synthesis via Activation of C–C Bonds.\u003c\/p\u003e \u003cp\u003e5.4 Conclusions and Outlook.\u003c\/p\u003e \u003cp\u003eAcknowledgments.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e6 Recent Progress in the Metathesis Reaction\u003c\/b\u003e (\u003ci\u003eMiwako Mori\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e6.1 Introduction.\u003c\/p\u003e \u003cp\u003e6.2 Olefin Metathesis.\u003c\/p\u003e \u003cp\u003e6.3 Enyne Metathesis.\u003c\/p\u003e \u003cp\u003e6.4 Alkyne Metathesis.\u003c\/p\u003e \u003cp\u003e6.5 Conclusions.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e7 Nonlinear Effects in Asymmetric Catalysis\u003c\/b\u003e (\u003ci\u003eHenri B. Kagan\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e7.1 Introduction.\u003c\/p\u003e \u003cp\u003e7.2 Properties of Enantiomer Mixtures.\u003c\/p\u003e \u003cp\u003e7.3 Nonlinear Effect in Asymmetric Catalysis.\u003c\/p\u003e \u003cp\u003e7.4 Main Classes of Reactions.\u003c\/p\u003e \u003cp\u003e7.5 Asymmetric Amplification.\u003c\/p\u003e \u003cp\u003e7.6 Current Trends.\u003c\/p\u003e \u003cp\u003e7.7 Conclusion.\u003c\/p\u003e \u003cp\u003eAcknowledgment.\u003c\/p\u003e \u003cp\u003eReferences and Notes.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e8 Asymmetric Activation and Deactivation of Racemic Catalysts\u003c\/b\u003e (\u003ci\u003eKoichi Mikami and Kohsuke Aikawa\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e8.1 Introduction.\u003c\/p\u003e \u003cp\u003e8.2 Racemic Catalysis.\u003c\/p\u003e \u003cp\u003e8.2.1 Asymmetric Deactivation.\u003c\/p\u003e \u003cp\u003e8.3 Future Perspectives.\u003c\/p\u003e \u003cp\u003eReferences and Notes.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e9 Asymmetric Autocatalysis with Amplification of Chirality and Origin of Chiral Homogeneity of Biomolecules\u003c\/b\u003e (\u003ci\u003eKenso Soai, Tsuneomi Kawasaki, and Itaru Sato\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e9.1 Introduction.\u003c\/p\u003e \u003cp\u003e9.2 Asymmetric Autocatalysis.\u003c\/p\u003e \u003cp\u003e9.3 Amplification of Chirality by Asymmetric Autocatalysis.\u003c\/p\u003e \u003cp\u003e9.4 Asymmetric Autocatalysis and Its Role in the Origin and Amplification of Chirality.\u003c\/p\u003e \u003cp\u003e9.5 Conclusions.\u003c\/p\u003e \u003cp\u003eAcknowledgment.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e10 Recent Advances in Catalytic Asymmetric Desymmetrization Reactions\u003c\/b\u003e (\u003ci\u003eTomislav Rovis\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e10.1 Introduction.\u003c\/p\u003e \u003cp\u003e10.2 Allylic Alkylation.\u003c\/p\u003e \u003cp\u003e10.3 Ring Opening of Epoxides and Aziridines.\u003c\/p\u003e \u003cp\u003e10.4 Ring Opening of Bridged Systems.\u003c\/p\u003e \u003cp\u003e10.5 Olefin Metathesis.\u003c\/p\u003e \u003cp\u003e10.6 Acylation.\u003c\/p\u003e \u003cp\u003e10.7 Asymmetric Deprotonation.\u003c\/p\u003e \u003cp\u003e10.8 Oxidations.\u003c\/p\u003e \u003cp\u003e10.9 Cyclic Anhydride Desymmetrization.\u003c\/p\u003e \u003cp\u003e10.10 Miscellaneous.\u003c\/p\u003e \u003cp\u003e10.11 Concluding Remarks.\u003c\/p\u003e \u003cp\u003eAcknowledgments.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e11 History and Perspective of Chiral Organic Catalysts\u003c\/b\u003e (\u003ci\u003eGerald Lelais and David W. C. MacMillan\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e11.1 Introduction.\u003c\/p\u003e \u003cp\u003e11.2 Historical Background.\u003c\/p\u003e \u003cp\u003e11.3 Iminium Catalysis: A New Concept in Organocatalysis.\u003c\/p\u003e \u003cp\u003e11.4 Enamine Catalysis: Birth, Rebirth, and Rapid Growth.\u003c\/p\u003e \u003cp\u003e11.5 Brønsted Acid Catalysis: Hydrogen-Bonding Activation.\u003c\/p\u003e \u003cp\u003e11.6 Phase Transfer Catalysis (PTC).\u003c\/p\u003e \u003cp\u003e11.7 Future Perspective.\u003c\/p\u003e \u003cp\u003eAcknowledgments.\u003c\/p\u003e \u003cp\u003eReferences and Notes.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e12 Chiral Br\u003c\/b\u003e\u003cb\u003eø\u003c\/b\u003e\u003cb\u003ensted\/Lewis Acid Catalysts\u003c\/b\u003e (\u003ci\u003eKazuaki Ishihara and Hisashi Yamamoto\u003c\/i\u003e).\u003c\/p\u003e \u003cp\u003e12.1 Introduction.\u003c\/p\u003e \u003cp\u003e12.2 Chiral Brønsted Acid Catalysts.\u003c\/p\u003e \u003cp\u003e12.3 Chiral Lewis Acid Catalysts.\u003c\/p\u003e \u003cp\u003e12.4 Lewis Acid--Assisted Chiral Brønsted Acid Catalysts.\u003c\/p\u003e \u003cp\u003e12.5 Conclusions and Outlook.\u003c\/p\u003e \u003cp\u003eReferences.\u003c\/p\u003e \u003cp\u003e\u003cb\u003e13 Chiral Bifunctional Acid\/Base Catalysts\u003c\/b\u003e (\u003ci\u003eMasakatsu Shibasaki and Motomu Kanai\u003c\/i\u003e)\u003c\/p\u003e \u003cp\u003e13.1 Introduction.\u003c\/p\u003e \u003cp\u003e13.2 Chiral Bro¨nsted Base Catalysis.\u003c\/p\u003e \u003cp\u003e13.3 Chiral Bronsted Base--Lewis Acid Bifunctional Catalysis.\u003c\/p\u003e \u003cp\u003e13.4 Chiral Bronsted Base--Bronsted Acid Bifunctional Catalysis.\u003c\/p\u003e \u003cp\u003e13.5 Chiral Lewis Base Catalysis.\u003c\/p\u003e \u003cp\u003e13.6 Chiral Lewis Base--Lewis Acid Bifunctional Catalysis.\u003c\/p\u003e \u003cp\u003e13.7 Conclusion.\u003c\/p\u003e \u003cp\u003eReferences and Notes.\u003c\/p\u003e \u003cp\u003eIndex.\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Chemistry [\u003ca title=\"See our other books on Chemistry\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Chemistry%20%5BPN%5D%22\"\u003ePN\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Wiley-Interscience","offers":[{"title":"Brand New","offer_id":52298027925784,"sku":"9780471680260","price":99.49,"currency_code":"GBP","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/files\/9780471680260.jpg?v=1781731598","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/new-frontiers-in-asymmetric-catalysis-hardback-9780471680260","provider":"Freshly Printed Books","version":"1.0","type":"link"}