{"product_id":"multiparametric-ultrasound-for-the-assessment-of-diffuse-liver-disease-a-practical-approach-paperback-9780323874793","title":"Multiparametric Ultrasound for the Assessment of Diffuse Liver Disease; A Practical Approach (Paperback \/ softback) 9780323874793","description":"\u003cfont face=\"Georgia\"\u003e\r\n\u003cp\u003e\u003cfont size=\"6\"\u003eMultiparametric Ultrasound for the Assessment of Diffuse Liver Disease\u003c\/font\u003e\u003cbr\u003e\r\n\u003cfont size=\"5\"\u003eA Practical Approach\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cem\u003eMake the most of liver ultrasound elastography for more efficient diagnoses and effective treatment\u003c\/em\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003cp\u003e\u003cfont size=\"4\"\u003eRichard G. Barr (Edited by), Giovanna Ferraioli (Edited by)\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e9780323874793, Elsevier Health Sciences\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003ePaperback \/ softback, published 8 November 2022\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e256 pages\u003cbr\u003e23.5 x 19 x 1.7 cm, 0.41 kg\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\r\n\r\n\r\n\u003cp align=\"justify\"\u003e\u003cstrong\u003e\u003cfont size=\"3\"\u003eFor those who treat and diagnose liver disease, whether radiologists, emergency medical physicians, hepatologists, or sonographers, a clear understanding of the strict protocol needed to obtain accurate measurements is essential. Multiparametric Ultrasound for the Assessment of Diffuse Liver Disease offers a practical approach to liver shear wave elastography acquisition from globally recognized leaders in the field. It answers critical questions such as how to use each of the current techniques to best characterize your patients’ liver disease, how to deal with the limitations of each of these techniques, and what to ask—and not to ask—of your devices and software.\u003cul\u003e \u003cli\u003e  \u003cp\u003ePresents an overview of conventional ultrasound findings in chronic liver disease and portal hypertension, and presents the basic concepts and protocols needed to measure liver stiffness and interpret liver stiffness values. \u003c\/p\u003e\n\u003c\/li\u003e \u003cli\u003e  \u003cp\u003eDetails clinical applications, artifacts, and guidelines of liver ultrasound elastography, including tips and tricks. \u003c\/p\u003e\n\u003c\/li\u003e \u003cli\u003e  \u003cp\u003eReviews the latest ultrasound techniques to assess liver steatosis and focal liver lesions, as well as the uses of new technologies of fat quantification and dispersion. \u003c\/p\u003e\n\u003c\/li\u003e \u003cli\u003e  \u003cp\u003eAn eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. \u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003c\/font\u003e\u003c\/strong\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003e\u003cp\u003e1. Introduction (basics of chronic liver disease – incidence, etc.)\u003c\/p\u003e \u003cp\u003eGuadalupe Garcia-Tsao (Yale University School of Medicine, CT, USA)\u003c\/p\u003e \u003cp\u003eChronic liver disease is a substantial world-wide problem. It can be due to a wide range of etiologic agents. Any process that leads to chronic inflammation can progress to chronic liver disease. Its major consequence is increasing deposition of fibrous tissue within the liver leading to cirrhosis with its complications, such as portal hypertension, hepatic insufficiency and hepatocellular carcinoma.\u003c\/p\u003e \u003cp\u003eKey words: chronic liver disease, liver fibrosis, shear wave elastography, hepatitis B, hepatitis C, NAFLD, NASH.\u003c\/p\u003e \u003cp\u003e2. Liver stiffness measurement techniques basics\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Mark L Palmeri (Duke University, NC, USA), Richard G Barr\u003c\/p\u003e \u003cp\u003eLiver elastography can be performed with various techniques. These include both ultrasound-based elastography and magnetic resonance elastography. The ultrasound methods include strain elastography (SE), VCTE, and ARFI techniques (pSWE and 2D-SWE). SE is limited in evaluation of liver stiffness and will not be presented in this book.\u003c\/p\u003e \u003cp\u003eKey words: VCTE, pSWE, 2D-SWE, ARFI, shear wave elastography, MRE, vibration elastography, phantom studies.\u003c\/p\u003e \u003cp\u003ea. TE\u003c\/p\u003e \u003cp\u003eb. ARFI techniques\u003c\/p\u003e \u003cp\u003ec. MRE\u003c\/p\u003e \u003cp\u003ed. Vibratory Techniques\u003c\/p\u003e \u003cp\u003e3. Protocol for acquisition\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Richard G Barr\u003c\/p\u003e \u003cp\u003eFor all of the ultrasound techniques (vibration-controlled transient elastography, point shear wave elastography and two-dimensional shear wave elastography) the patient is studied in the supine or slight left lateral decubitus position. The protocol for a correct acquisition will be presented in details.\u003c\/p\u003e \u003cp\u003eKey words: VCTE, pSWE, 2D-SWE, ARFI, shear wave elastography, liver stiffness.\u003c\/p\u003e \u003cp\u003ea. General protocol\u003c\/p\u003e \u003cp\u003eb. Quality Assessment\u003c\/p\u003e \u003cp\u003ei. Vendor specific quality assessment\u003c\/p\u003e \u003cp\u003e4. Tips and Tricks\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Richard Barr\u003c\/p\u003e \u003cp\u003eFor a reliable acquisition, several factors should be taken into account. They include depth for measurement, presence of liver steatosis, transducer frequency, transducer position, number of measurements, confounders and so on. All these factors will be analyzed in details. \u003c\/p\u003e \u003cp\u003eKey words: reliability, accuracy studies.\u003c\/p\u003e \u003cp\u003e5. Artifacts\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Mark Palmeri (Duke University, NC, USA), Richard G Barr\u003c\/p\u003e \u003cp\u003eIdentification of the artifacts is of outmost importance for the interpretation. Knowing them is also important for acquiring the best images for accurate diagnosis.\u003c\/p\u003e \u003cp\u003eKey words: reverberation, attenuation, failure, phantoms studies.\u003c\/p\u003e \u003cp\u003ea. TE\u003c\/p\u003e \u003cp\u003eb. ARFI techniques\u003c\/p\u003e \u003cp\u003ec. MRE\u003c\/p\u003e \u003cp\u003e6. Staging liver fibrosis with shear wave elastography\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Davide Roccarina (Careggi University Hospital, Florence, Italy), Jonathan Dillman (University of Cincinnati College of Medicine, OH, USA), Richard G Barr\u003c\/p\u003e \u003cp\u003eAs of today, shear wave elastography has been accepted as a reliable substitute of liver biopsy in several clinical scenarios, mainly in patients with viral etiologies and\/or NAFLD\/NASH. The role of shear wave elastography in several etiologies of liver disease and in the pediatric population will be presented. \u003c\/p\u003e \u003cp\u003eKey words: liver stiffness, hepatitis B, hepatitis C, NAFLD, NASH, primary sclerosing cholangitis, autoimmune hepatitis, alcoholic hepatitis, cystic fibrosis, biliary atresia, Fontan circulation, children.\u003c\/p\u003e \u003cp\u003ea. Viral etiologies\u003c\/p\u003e \u003cp\u003eb. NAFLD\/NASH\u003c\/p\u003e \u003cp\u003ec. Other etiologies\u003c\/p\u003e \u003cp\u003ed. Pediatrics\u003c\/p\u003e \u003cp\u003e7. Portal hypertension: liver and spleen stiffness\u003c\/p\u003e \u003cp\u003eDavide Roccarina (Careggi University Hospital, Florence, Italy)\u003c\/p\u003e \u003cp\u003eLiver stiffness correlates with the severity of liver fibrosis up to the threshold of clinically significant portal hypertension. At this stage, the strength of the correlation between liver stiffness and fibrosis decreases, probably due to an increasing role played by extrahepatic factors. It has been shown that spleen stiffness correlates better than liver stiffness with the portal pressures. Studies will be presented. \u003c\/p\u003e \u003cp\u003eKey words: HVPG, portal hypertension, stiffness.\u003c\/p\u003e \u003cp\u003e8. Liver stiffness beyond the staging of liver fibrosis\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Richard G Barr\u003c\/p\u003e \u003cp\u003eAn increase of liver stiffness has been reported in patients with liver congestion. It is a \"confounding factor\" for the evaluation of liver fibrosis. However, in the setting of right-sided heart failure liver stiffness seems directly influenced by central venous pressure and can be used as a prognostic marker to predict cardiac events.\u003c\/p\u003e \u003cp\u003eKey words: heart failure, liver congestion, hepatic sinusoidal obstruction, Fontan circulation, Budd Chiari syndrome, valvular diseases.\u003c\/p\u003e \u003cp\u003e9. Guideline\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Richard G Barr\u003c\/p\u003e \u003cp\u003eThe availability of accurate non-invasive methods for the assessment of liver fibrosis was an important breakthrough and has prompted ultrasound federations of societies as well as clinical or radiological societies to issue international guidelines or consensus on the clinical applications of the SWE techniques. This chapter presents the most important guidelines from a practical point of view.\u003c\/p\u003e \u003cp\u003eKey words: guidelines, WFUMB, EFSUMB, SRU, shear wave elastography, diffuse liver disease, chronic viral hepatitis, ARFI techniques, NAFLD.\u003c\/p\u003e \u003cp\u003ea. Reporting results\u003c\/p\u003e \u003cp\u003e10. Non-invasive assessment of liver steatosis with US techniques\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Richard G Barr\u003c\/p\u003e \u003cp\u003eAn accurate estimation of the fat in the liver is important in the diagnostic work-up of patients with non-alcoholic fatty liver disease. Ultrasound methods of fat quantification have been developed. They will be presented in details.\u003c\/p\u003e \u003cp\u003eKey words: attenuation coefficient, ATI, ATT, UGAP, backscatter coefficient, speed of sound, steatosis.\u003c\/p\u003e \u003cp\u003e11. Dispersion\u003c\/p\u003e \u003cp\u003eKatsutoshi Sugimoto (Tokyo Medical University, Japan), Giovanna Ferraioli, Richard G Barr\u003c\/p\u003e \u003cp\u003eThe shear wave speed obtained in liver stiffness estimation is dependent on the ARFI frequency. The dispersion is the estimate of the stiffness at various ARFI frequencies. The relationship between dispersion and inflammation will be presented. Detection and grading of inflammation would add important information in the diagnosis, management, and follow-up of patients with chronic liver diseases. \u003c\/p\u003e \u003cp\u003eKey words: necro-inflammation, ARFI frequency, shear wave elastography.\u003c\/p\u003e \u003cp\u003e12. Focal liver lesions – short section \u003c\/p\u003e \u003cp\u003eStephanie R Wilson (University of Calgary, Canada)\u003c\/p\u003e \u003cp\u003eSeveral reports document that malignant lesions are more likely stiffer than benign lesions. However, there is significant overlap. Both benign and malignant lesions can be soft or stiff compared to normal liver. In addition, the stiffness of the liver varies significantly with fibrosis.\u003c\/p\u003e \u003cp\u003eKey words: hemangioma, focal steatosis, focal nodular hyperplasia, hepatocellular carcinoma, cholangiocarcinoma, liver metastasis.\u003c\/p\u003e \u003cp\u003e13. Conclusions\u003c\/p\u003e \u003cp\u003eGiovanna Ferraioli, Richard G Barr\u003c\/p\u003e \u003cp\u003eThe value of shear wave elastography in diffuse liver disease will be highlighted.\u003c\/p\u003e \u003cp\u003eKey words: shear wave elastography, liver stiffness, spleen stiffness, liver steatosis, chronic liver disease.\u003c\/p\u003e\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\u003cp\u003e\u003cfont size=\"3\"\u003eSubject Areas: Radiology [\u003ca title=\"See our other books on Radiology\" href=\"https:\/\/freshlyprintedbooks.co.uk\/search?q=%22Radiology%20%5BMMPH%5D%22\"\u003eMMPH\u003c\/a\u003e]\u003c\/font\u003e\u003c\/p\u003e\r\n\r\n\r\n\u003c\/font\u003e","brand":"Elsevier","offers":[{"title":"Default Title","offer_id":46648520147224,"sku":"9780323874793","price":78.39,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0730\/2037\/5320\/products\/9780323874793.jpg?v=1694992335","url":"https:\/\/freshlyprintedbooks.co.uk\/products\/multiparametric-ultrasound-for-the-assessment-of-diffuse-liver-disease-a-practical-approach-paperback-9780323874793","provider":"Freshly Printed Books","version":"1.0","type":"link"}